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山东大学 [5]
西安交通大学 [4]
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厦门大学 [1]
中国农业科学院 [1]
华南理工大学 [1]
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期刊论文 [16]
学位论文 [3]
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Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice
期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:
Li, Xiaopeng
;
Wu, Qian
;
Sui, Yong
;
Li, Shuyi
;
Xie, Bijun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/27
A-type procyanidins
Oxidative stress
Glucose homeostasis
Type 2 diabetes
mTOR
ACC1
acetyl coenzyme A carboxylase 1
ACL
ATP-citrate lyase
ALT
alanine aminotransferase
AST
aspartate aminotransferase
AUC
area under curve
BAT
brown adipose tissue
FAS
fatty acid synthase
FFA
free fatty acid
FoxO3a
Forkhead box O3a
FoxO1a
Forkhead box O3a
PKCβ
protein kinase C β
mTOR
mechanistic target of rapamycin
HDL
high-density lipoprotein
GHbA1c
glycated hemoglobin A1c
GK
glucokinase
G-6-Pase
glucose-6-phosphatase
GLP-1
glucagon-like peptide-1
GSH-PX
total glutathione peroxidase
HOMA-IR
homeostatic model assessment of insulin resistance
LDHA
lactate dehydrogenase
LDL
low-density lipoprotein
LPOPC
oligomeric procyanidins of litchi pericarp
MDA
malondialdehyde
MnSOD
manganese superoxide dismutase
mTOR
mechanistic target of rapamycin
OGTT
oral glucose tolerance test
PDH
pyruvate dehydrogenase
PEPCK
phosphoenolpyruvate carboxykinase
PFK
phosphofructokinase
PK
pyruvate kinase
PKCβ
protein kinase C β
PPG
postprandial blood glucose
S6K1
S6 Kinase 1
PKCβ
protein kinase C β
RTK
receptor tyrosine kinase
SREBP-1c
sterol regulatory element-binding protein 1c
ACL
ATP-citrate lyase
ACC1
acetyl coenzyme A carboxylase 1
FAS
fatty acid synthase
SCD1
stearoyl CoA desaturase 1
STZ
streptozotocin
S6K1
S6 kinase 1
PPG
postprandial blood glucose
ROS
reactive oxygen species
TC
total cholesterol
TG
triacylglycerol
STZ
streptozotocin
T-AOC
total antioxidant capacity
T-SOD
total superoxide dismutase
UCP-1
uncoupling protein 1
WAT
white adipose tissue
XOS
xylo-oligosaccharides
Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.
期刊论文
Frontiers in genetics, 2017, 卷号: 8, 页码: 113
作者:
Ito Takashi K
;
Lu Chenhao
;
Khan Jacob
;
Nguyen Quy
;
Huang Heather Z
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  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
mTORC1
mitochondrial disease
liver
lifespan
S6K1
Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency (vol 8, 113, 2017)
期刊论文
FRONTIERS IN GENETICS, 2017, 卷号: 8
作者:
Ito, Takashi K.
;
Lu, Chenhao
;
Khan, Jacob
;
Quy Nguyen
;
Huang, Heather Z.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
mitochondrialdisease
lifespan
liver
mTORC1
S6K1
Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia
期刊论文
2017, 卷号: 18, 期号: 9, 页码: 2088-2095
作者:
Liu, Hongqi
;
Feng, Xizhi
;
Ennis, Kelli N.
;
Behrmann, Catherine A.
;
Sarma, Pranjal
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  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
AD80
AXL
BMS-777607
LY-2779964
PF4708671
Pten
S6K1
TAM
glioblastoma
leukemia
PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester
期刊论文
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2015, 卷号: 60, 页码: 34-42
作者:
Ni, Yang
;
Wang, Liguang
;
Zhang, Jihong
;
Pang, Zhaofei
;
Liu, Qi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
Protein kinase D1
mTOR
S6K1
S6
Non-small cell lung cancer
Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 卷号: 15, 期号: [db:dc_citation_issue], 页码: 3154-3171
作者:
Zhang, Tao
;
Qu, Shanna
;
Shi, Qi
;
He, Dalin
;
Jin, Xunbo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
S6K1
bladder cancer
TRAIL
Mcl-1
mTOR
evodiamine
Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP
期刊论文
ANTI-CANCER DRUGS, 2014, 卷号: 25, 期号: [db:dc_citation_issue], 页码: 887-897
作者:
Zhang, Tao
;
Wang, Xinyang
;
He, Dalin
;
Jin, Xunbo
;
Guo, Peng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
AMPK
S6K1
bladder cancer
c-FLIP
TRAIL
mTOR
metformin
一种具有高效低毒抗肝癌效应的熊去氧胆酸衍生物的筛选及初步机制探讨
学位论文
2014, 2013
罗强
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2016/01/13
UDCA
U12
肝癌
mTOR/S6K1信号通路
细胞周期
UDCA
U12
liver cancer
mTOR/S6k1 pathway
cell cycle
Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1
期刊论文
International Journal of Molecular Sciences, 2014, 期号: 2, 页码: 3154-3171
作者:
Zhang Tao
;
Qu Shanna
;
Shi Qi
;
He Dalin
;
Jin Xunbo
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/17
evodiamine
TRAIL
Mcl-1
mTOR
S6K1
bladder cancer
Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP
期刊论文
Anti-Cancer Drugs, 2014, 卷号: 25, 期号: 8, 页码: 887-897
作者:
Tao.Zhang
;
Xinyang.Wang
;
Dalin.He
;
Xunbo.Jin
;
Peng.Guo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
AMPK
bladder cancer
c-FLIP
metformin
mTOR
S6K1
TRAIL
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