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Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice 期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:  Li, Xiaopeng;  Wu, Qian;  Sui, Yong;  Li, Shuyi;  Xie, Bijun
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/27
A-type procyanidins  Oxidative stress  Glucose homeostasis  Type 2 diabetes  mTOR  ACC1  acetyl coenzyme A carboxylase 1  ACL  ATP-citrate lyase  ALT  alanine aminotransferase  AST  aspartate aminotransferase  AUC  area under curve  BAT  brown adipose tissue  FAS  fatty acid synthase  FFA  free fatty acid  FoxO3a  Forkhead box O3a  FoxO1a  Forkhead box O3a  PKCβ  protein kinase C β  mTOR  mechanistic target of rapamycin  HDL  high-density lipoprotein  GHbA1c  glycated hemoglobin A1c  GK  glucokinase  G-6-Pase  glucose-6-phosphatase  GLP-1  glucagon-like peptide-1  GSH-PX  total glutathione peroxidase  HOMA-IR  homeostatic model assessment of insulin resistance  LDHA  lactate dehydrogenase  LDL  low-density lipoprotein  LPOPC  oligomeric procyanidins of litchi pericarp  MDA  malondialdehyde  MnSOD  manganese superoxide dismutase  mTOR  mechanistic target of rapamycin  OGTT  oral glucose tolerance test  PDH  pyruvate dehydrogenase  PEPCK  phosphoenolpyruvate carboxykinase  PFK  phosphofructokinase  PK  pyruvate kinase  PKCβ  protein kinase C β  PPG  postprandial blood glucose  S6K1  S6 Kinase 1  PKCβ  protein kinase C β  RTK  receptor tyrosine kinase  SREBP-1c  sterol regulatory element-binding protein 1c  ACL  ATP-citrate lyase  ACC1  acetyl coenzyme A carboxylase 1  FAS  fatty acid synthase  SCD1  stearoyl CoA desaturase 1  STZ  streptozotocin  S6K1  S6 kinase 1  PPG  postprandial blood glucose  ROS  reactive oxygen species  TC  total cholesterol  TG  triacylglycerol  STZ  streptozotocin  T-AOC  total antioxidant capacity  T-SOD  total superoxide dismutase  UCP-1  uncoupling protein 1  WAT  white adipose tissue  XOS  xylo-oligosaccharides  
Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency. 期刊论文
Frontiers in genetics, 2017, 卷号: 8, 页码: 113
作者:  Ito Takashi K;  Lu Chenhao;  Khan Jacob;  Nguyen Quy;  Huang Heather Z
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/26
Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency (vol 8, 113, 2017) 期刊论文
FRONTIERS IN GENETICS, 2017, 卷号: 8
作者:  Ito, Takashi K.;  Lu, Chenhao;  Khan, Jacob;  Quy Nguyen;  Huang, Heather Z.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia 期刊论文
2017, 卷号: 18, 期号: 9, 页码: 2088-2095
作者:  Liu, Hongqi;  Feng, Xizhi;  Ennis, Kelli N.;  Behrmann, Catherine A.;  Sarma, Pranjal
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/04
PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester 期刊论文
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2015, 卷号: 60, 页码: 34-42
作者:  Ni, Yang;  Wang, Liguang;  Zhang, Jihong;  Pang, Zhaofei;  Liu, Qi
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/17
Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 卷号: 15, 期号: [db:dc_citation_issue], 页码: 3154-3171
作者:  Zhang, Tao;  Qu, Shanna;  Shi, Qi;  He, Dalin;  Jin, Xunbo
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP 期刊论文
ANTI-CANCER DRUGS, 2014, 卷号: 25, 期号: [db:dc_citation_issue], 页码: 887-897
作者:  Zhang, Tao;  Wang, Xinyang;  He, Dalin;  Jin, Xunbo;  Guo, Peng
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
一种具有高效低毒抗肝癌效应的熊去氧胆酸衍生物的筛选及初步机制探讨 学位论文
2014, 2013
罗强
收藏  |  浏览/下载:5/0  |  提交时间:2016/01/13
Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1 期刊论文
International Journal of Molecular Sciences, 2014, 期号: 2, 页码: 3154-3171
作者:  Zhang Tao;  Qu Shanna;  Shi Qi;  He Dalin;  Jin Xunbo
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/17
Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP 期刊论文
Anti-Cancer Drugs, 2014, 卷号: 25, 期号: 8, 页码: 887-897
作者:  Tao.Zhang;  Xinyang.Wang;  Dalin.He;  Xunbo.Jin;  Peng.Guo
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/17


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