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Receptor-Ligand Binding: Effect of Mechanical Factors
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 10, 2023, 卷号: 24, 页码: 9062
作者:
Du, Ruotian
;
Li L(李龙)
;
Ji, Jing
;
Fan, Yubo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/06/15
receptor-ligand binding
tension
shear stress
stretch
compression
substrate stiffness
biomechanics
mechanotransduction
Interplay of receptor-ligand binding and lipid domain formation during cell adhesion
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 1019477
作者:
Li L(李龙)
;
Hu, Jinglei
;
Rozycki, Bartosz
;
Ji, Jing
;
Song F(宋凡)
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/10/23
cell adhesion
receptor-tigand binding
lipid domain formation
binding affinity
binding cooperativity
phase separation
Insights into intercellular receptor-ligand binding kinetics in cell communication
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 953353
作者:
An, Chenyi
;
Wang, Xiaohuan
;
Song F(宋凡)
;
Hu, Jinglei
;
Li L(李龙)
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/10/23
cell communication
intercellular receptor-ligand binding kinetics
protein-membrane interaction
biomechanical force
bioelectric microenvironment
Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
期刊论文
FRONTIERS IN PHYSIOLOGY, 2022, 卷号: 12, 页码: 12
作者:
Guo, Zhuojun
;
Liao, Xin
;
Chen, J. -Y.(陈均远)
;
He, Chunpeng
;
Lu, Zuhong
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  |  
浏览/下载:29/0
  |  
提交时间:2022/02/24
reef-building coral
budding reproduction
receptor tyrosine kinase
full-length transcriptome
FGF-FGFR binding models
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
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  |  
浏览/下载:43/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 9
作者:
Li L(李龙)
;
Wang XH(王小环)
;
Wu, Helong
;
Shao YF(邵颖峰)
;
Wu, Huaping
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  |  
浏览/下载:94/0
  |  
提交时间:2021/05/31
cell adhesion
receptor-ligand binding
nanoscale lipid cluster
ligand mobility
phase separation
binding constant
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
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  |  
浏览/下载:19/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay
Mechanistic in silico modeling of bisphenols to predict estrogen and glucocorticoid disrupting potentials
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 728, 页码: 1-11
作者:
Chen, Qinchang
;
Zhou, Chengzhuo
;
Shi, Wei
;
Wang, Xiaoxiang
;
Xia, Pu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/14
Endocrine disruptor
Estrogen receptor
Glucocorticoid receptor
Coregulators
Accelerated molecular dynamics simulations
Binding free energy
Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Hongli
;
Zhang, Qianqian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
CC chemokine receptor 2
orthosteric antagonist
allosteric antagonist
binding cooperativity
metadynamics simulation
Gaussian accelerated MD simulation
A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein
期刊论文
CURRENT BIOLOGY, 2020, 卷号: 30, 期号: 11, 页码: 2196-+
作者:
Zhou, Hong
;
Chen, Xing
;
Hu, Tao
;
Li, Juan
;
Song, Hao
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/08/07
RECEPTOR-BINDING DOMAIN
AVIAN INFLUENZA-VIRUS
ORIGIN
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