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上海药物研究所 [38]
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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
收藏
  |  
浏览/下载:239/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Baseline anemia predicts a poor prognosis in patients with non-small cell lung cancer with epidermal growth factor receptor mutations: a retrospective study
期刊论文
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wei, Jingwen
;
Xiang, Jing
;
Hao, Yue
;
Si, Jinfei
;
Wang, Wenxian
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
Anemia
Epidermal growth factor receptor
Epidermal growth factor receptor tyrosine kinase inhibitors
Non-small cell lung cancer
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China
期刊论文
THORACIC CANCER, 2022
作者:
Xu, Chunwei
;
Si, Lu
;
Wang, Wenxian
;
Li, Ziming
;
Song, Zhengbo
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/12/22
fusion
precision medicine
solid tumor
targeted therapy
tyrosine receptor kinase
Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
期刊论文
FRONTIERS IN PHYSIOLOGY, 2022, 卷号: 12, 页码: 12
作者:
Guo, Zhuojun
;
Liao, Xin
;
Chen, J. -Y.(陈均远)
;
He, Chunpeng
;
Lu, Zuhong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/02/24
reef-building coral
budding reproduction
receptor tyrosine kinase
full-length transcriptome
FGF-FGFR binding models
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
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  |  
浏览/下载:36/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:
Lai Mengzhen
;
Song Peiran
;
Dou Dou
;
Diao Yanyan
;
Tong Linjiang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton’s tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
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