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科研机构
山东大学 [11]
西安交通大学 [3]
复旦大学上海医学院 [3]
上海药物研究所 [2]
武汉轻工大学 [2]
武汉大学 [2]
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期刊论文 [36]
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2019 [1]
2018 [4]
2017 [3]
2016 [8]
2015 [6]
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High mobility group box-1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition
期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2019, 卷号: 25, 期号: 36
作者:
Ye, Ting-Jie
;
Lu, Yan-Lin
;
Yan, Xiao-Feng
;
Hu, Xu-Dong
;
Wang, Xiao-Ling
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
Sirtuin1
Poly ADP-ribose polymerase 1
High mobility group box-1
Hepatocytes
Hydrogen peroxide
Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression
期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 3, 页码: 821-831
作者:
Wang, Yu-Ting
;
Yuan, Bo
;
Chen, Hua-Dong
;
Xu, Lin
;
Tian, Yu-Nan
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
53BP1
acquired resistance
phosphatase and tensin homolog deficiency
poly(ADP-ribose) polymerase inhibitors
SAMHD1
Expression of DNA Damage Response Proteins and Associations with Clinicopathologic Characteristics in Chinese Familial Breast Cancer Patients with BRCA1/2 Mutations
期刊论文
JOURNAL OF BREAST CANCER, 2018, 卷号: 21, 期号: 3
作者:
Zhu, Xinyi
;
Tian, Tian
;
Ruan, Miao
;
Rao, Jia
;
Yang, Wentao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
BRCA1 genes
BRCA2 genes
Breast neoplasms
DNA repair
Poly (ADP-ribose) polymerase-1
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Potential role of HGF-PARP-1 signaling in invasion of ovarian cancer cells
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2018, 卷号: 11, 期号: 7, 页码: 3310-3317
作者:
Wei, Wei
;
Lv, Shuqing
;
Zhang, Cancan
;
Tian, Yongjie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Hepatocyte growth factor (HGF)
ovarian cancer
invasion
poly
(ADP-ribose) polymerase-1
The expression of APE1 in triple-negative breast cancer and its effect on drug sensitivity of olaparib.
期刊论文
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, 卷号: 39, 期号: 10
作者:
Chen Tianran
;
Liu Chuan
;
Lu Heng
;
Yin Mingzhen
;
Shao Changjuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
BER
Poly (ADP-ribose) polymerase 1 inhibitor
apurinic/apyrimidyl endonuclease 1
olaparib
triple-negative breast cancer
Poly(ADP-ribose) polymerase 1 deficiency increases nitric oxide production and attenuates aortic atherogenesis through downregulation of arginase II
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2017, 卷号: 44, 期号: 1, 页码: 114-122
作者:
Wei, Shu-jian
;
Cheng, Lin
;
Liang, Er-shun
;
Wang, Qi
;
Zhou, Sheng-nan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
arginase II
atherogenesis
nitric oxide
poly (ADP-ribose) polymerase 1
Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents
期刊论文
2017, 卷号: 50, 期号: 1, 页码: 223-231
作者:
Chen, Yang
;
Zhang, Huixian
;
He, Qiyang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
ubiquitin-conjugating protein 9
bleomycin hydrolase
poly(ADP-ribose) polymerase-1
drug resistance
antitumor agent
Impact of the PARP1 rs1136410 and rs3219145 polymorphisms on susceptibility and clinicopathologic features of breast cancer in a Chinese population
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2016, 卷号: 5, 期号: [db:dc_citation_issue], 页码: 520-528
作者:
Ma, Xiao-Bin
;
Wang, Xi-Jing
;
Wang, Meng
;
Dai, Zhi-Ming
;
Jin, Tian-Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
Poly(ADP-ribose) polymerase-1 (PARP1)
polymorphism
breast cancer (BC)
susceptibility
[The Protective Effect of Inhibition of PARP-1 on Inflammation Induced by PM2.5 in Human Bronchial Epithelial Cell Line.]
期刊论文
Sichuan Da Xue Xue Bao Yi Xue Ban, 2016, 卷号: Vol.47 No.6, 页码: 825-829
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/03/05
Inflammation
NF-κB
PM2.5
Poly
ADP-ribose
polymerase-1
(PARP-1)
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