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浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 页码: 2399-2402 作者:  Wang, Fangying;  Jiang, Hongxia;  Deng, Yufang;  Yu, Jiang;  Zhan, Miao 收藏  |  浏览/下载：2/0  |  提交时间：2019/11/26 Basal cell carcinoma  Hedgehog signaling pathway  Deuterium-hydrogen replacement  Pharmacokinetic properties  Deuterated drug  Vismodegib   Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties 期刊论文 Bioorganic and Medicinal Chemistry Letters, 2018 作者:  Fangying Wang;  Hongxia Jiang;  Yufang Deng;  Jiang Yu;  Miao Zhan 收藏  |  浏览/下载：8/0  |  提交时间：2019/02/25 Vismodegib  Hedgehog signaling pathway  Basal cell carcinoma  Deuterated drug  Deuterium-hydrogen replacement  Pharmacokinetic properties   Pharmacokinetic and Pharmacodynamic Properties of Cinacalcet (KRN1493) in Chinese Healthy Volunteers: A Randomized, Open-label, Single Ascending-dose and Multiple-dose, Parallel-group Study 期刊论文 2016, 卷号: 38, 期号: 2, 页码: 348-57 作者:  Liu Hongzhong;  Wang Hongyun;  Liu Tao;  Jiang Ji;  Chen Xia 收藏  |  浏览/下载：3/0  |  提交时间：2020/01/04 Chinese healthy volunteers  cinacalcet  pharmacodynamic properties  pharmacokinetic properties  secondary hyperparathyroidism   Synthesis and evaluation of 4-(2-pyrimidinylamino) benzamides inhibitors of hedgehog signaling pathway 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 983-988 作者:  Xin, Minhang;  Wen, Jun;  Tang, Feng;  Tu, Chongxing;  Huang, Wei 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03 SAR  Hedgehog signaling pathway  Pharmacokinetic properties  Inhibitors   An integrated drug-likeness study for bicyclic privileged structures: from physicochemical properties to in vitro ADME properties 期刊论文 MOLECULAR DIVERSITY, 2011, 卷号: 15, 期号: 4, 页码: 857-876 作者:   收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Physicochemical properties  Pharmacokinetic properties  Privileged structure  Drug-likeness  ADME   Interdisciplinary nanomedicine publications through interdisciplinary peer-review 图书章节 作者:  Owen, Andrew;  Rannard, Steve P.;  Bawa, Raj;  Feng, Si-Shen 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/02 Area under the curves  Bioavailability  Commercialization  Complimentary disciplines  European medicines agencies  Extrinsic properties  Interdisciplinary  Intrinsic property  Life scientists  Materials chemistry  Nanocarriers  Nanoprecipitates  Patent offices  Patent prosecution  Peer review  Physical scientist  Physiologically based pharmacokinetic models  Polymer conjugate  Synthetic chemistry  US Food and Drug Administration