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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Pharmacokinetics and pharmacodynamics of cinacalcet in patients with renal failure receiving hemodialysis and hemodiafiltration therapy
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2019, 卷号: 57, 期号: 6
作者:
Li, Zhongdong
;
Shi, Wenjuan
;
Tan, Xiuyan
;
Zhang, Minmin
;
Huang, Bihong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
cinacalcet
hemodiafiltration
hemodialysis
pharmacodynamics
pharmacokinetics
renal failure
Quantitative Comparison of the Efficacies of 5 First-Line Drugs for Primary Restless Leg Syndrome
期刊论文
JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 卷号: 59, 期号: 9
作者:
Zhang, Ningyuan
;
Li, Yunfei
;
Lv, Yinghua
;
Xu, Ling
;
Chen, Junchao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
modeling and simulation
pharmacodynamics
pharmacology
pharmacometrics
population pharmacokinetics
sleep medicine
The influence of telmisartan on metformin pharmacokinetics and pharmacodynamics
期刊论文
Journal of Pharmacological Sciences, 2019, 卷号: Vol.139 No.1, 页码: 37-41
作者:
Jiagen Wen
;
Meizi Zeng
;
Zhaoqian Liu
;
Honghao Zhou
;
Heng Xu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/25
Telmisartan
Metformin
Pharmacokinetics
Pharmacodynamics
Drug–drug
interaction
Xinjiang herbal tea exerts immunomodulatory activity via TLR2/4-mediated MAPK signaling pathways in RAW264.7 cells and prevents cyclophosphamide-induced immunosuppression in mice.
期刊论文
Journal of Ethnopharmacology, 2019, 卷号: Vol.228, 页码: 179-187
作者:
Bai, Yujia
;
Jiang, Yunyao
;
Liu, Tingwu
;
Li, Fu
;
Zhang, Jianmei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/12/13
ANIMAL
experimentation
*CELLULAR
signal
transduction
*CYTOKINES
*FLOW
cytometry
*GENE
expression
*IMMUNOLOGICAL
adjuvants
*IMMUNOSUPPRESSION
*INTERFERONS
*INTERLEUKINS
*MACROPHAGES
*MESSENGER
RNA
*MICE
*NITRIC
oxide
*OXIDOREDUCTASES
*TEA
*TUMOR
necrosis
factor
*DNA-binding
proteins
*NITRIC-oxide
synthases
*PLANT
extracts
*CYCLOPHOSPHAMIDE
(Drug)
*TOLL-like
receptors
*SIGNAL
peptides
*IN
vivo
studies
*PHARMACODYNAMICS
Population pharmacokinetics and dosing optimization of latamoxef in neonates and young infants
期刊论文
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2019, 卷号: 53, 期号: 3, 页码: 347-351
作者:
Qi, Hui
;
Kou, Chen
;
Qi, Yu-Jie
;
Tang, Bo-Hao
;
Wu, Yue-E
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Latamoxef
Population
Pharmacokinetics-pharmacodynamics
Neonates and
young infants
Cytotoxic seco-cytochalasins from an endophytic Aspergillus sp. harbored in Pinellia ternata tubers.
期刊论文
Fitoterapia, 2019, 卷号: Vol.132, 页码: 53-59
作者:
Xin, Xiao-Qian
;
Chen, Yao
;
Zhang, Hong
;
Li, Yun
;
Yang, Ming-Hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
CELL
lines
*DOSE-effect
relationship
in
pharmacology
*FUNGI
*MASS
spectrometry
*MEDICINAL
plants
*MOLECULAR
structure
*MYCOTOXINS
*RESEARCH
funding
*SPECTRUM
analysis
*CYTOTOXINS
*PHARMACODYNAMICS
Preparation and Evaluation of Irinotecan Poly(Lactic-co-Glycolic Acid) Nanoparticles for Enhanced Anti-tumor Therapy
期刊论文
AAPS PHARMSCITECH, 2019, 卷号: 20, 期号: 3
作者:
Yang, Xuehua
;
Yang, Ying
;
Jia, Qingwen
;
Hao, Yanyun
;
Liu, Jingjing
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
irinotecan
PLGA
nanoparticles
pharmacokinetics
pharmacodynamics
An evaluation of pitavastatin for the treatment of hypercholesterolemia
期刊论文
Expert Opinion on Pharmacotherapy, 2019, 卷号: Vol.20 No.1, 页码: 103-113
作者:
Paul Chan
;
Li Shao
;
Brian Tomlinson
;
Yuzhen Zhang
;
Zhong-Min Liu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
Hypercholesterolemia
pharmacokinetics
pharmacodynamics
pitavastatin
statins
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