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北京大学 [37]
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长春应用化学研究所 [12]
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期刊论文 [178]
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Label-Free Detection and Translocation Dynamics Study of Single-Molecule Herceptin Using Solid-State Nanopores
期刊论文
ADVANCED MATERIALS TECHNOLOGIES, 2022
作者:
Hu, Rui
;
Lu, Wenlong
;
Wei, Guanghao
;
Nan, Hexin
;
Li, Juan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
solid-state nanopore
single-molecule detection
protein dynamics
monoclonal antibody
protein unfolding
Study on Interaction of Coomassie Brilliant Blue G-250 with Bovine Serum Albumin by Multispectroscopic
期刊论文
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2021, 卷号: 27, 期号: 1, 页码: 421-431
作者:
Yang, Mingjun
;
Shi, Dongxiang
;
Wang, Yonggang
;
Ebadi, Abdol Ghaffar
;
Toughani, Mohsen
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/03/12
SMALL-MOLECULE
PROTEIN
BINDING
METHODOLOGIES
FLUORESCENCE
SPECTROSCOPY
SENSITIVITY
EXCITATION
MECHANISM
ASSAY
Mechanochemical Activation of Class-B G-Protein-Coupled Receptor upon Peptide-Ligand Binding
期刊论文
NANO LETTERS, 2020, 卷号: 20, 期号: 7, 页码: 5575-5582
作者:
Lo Giudice, Cristina
;
Zhang, Haonan
;
Wu, Beili
;
Alsteens, David
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Atomic force microscopy
single-molecule force spectroscopy
human glucagon receptor
G-protein-coupled receptors
mechanotransduction
A patent review of BRD4 inhibitors (2013-2019)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81
作者:
Lu, Tian
;
Lu, Wenchao
;
Luo, Cheng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Bromodomain-containing protein 4 (BRD4)
bromodomain and extra-terminal (BET) family
small molecule inhibitors
cancer
patent
therapeutic potential
Atomic Force Microscopy as a Powerful Multifunctional Tool for Probing the Behaviors of Single Proteins
期刊论文
IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2020, 卷号: 19, 期号: 1, 页码: 78-99
作者:
Li M(李密)
;
Wang YC(王越超)
;
Liu LQ(刘连庆)
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/02/17
Atomic force microscopy (AFM)
single-protein analysis
morphological imaging
single-molecule force recognition
mechanical unfolding
high-speed AFM
Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples
期刊论文
ENVIRONMENT INTERNATIONAL, 2019, 卷号: 132, 页码: -
作者:
Liu, Lanhua
;
Zhou, Xiaohong
;
Lu, Yun
;
Shi, Hanchang
;
Ma, Mei
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/10/23
Estrogen receptor
Small-molecule-protein conjugate
Optical fiber biosensor
17 beta-estradiol equivalent concentration
Wastewater sample
A patent review of arginine methyltransferase inhibitors (2010-2018)
期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:
Li, Xiao
;
Wang, Chen
;
Jiang, Hao
;
Luo, Cheng
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Arginine methylation
Protein arginine methyltransferases (PRMTs)
small molecule inhibitors
drug research and development
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
期刊论文
Cell chemical biology, 2019, 卷号: 26, 页码: 331-+
作者:
Mo Xiulei
;
Tang Cong
;
Niu Qiankun
;
Ma Tingxuan
;
Du Yuhong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/11/19
inhibitor of apoptosis protein
KRAS mutation
IAP antagonist
tumor and immune cell co-culture
small-molecule immunomodulator
IAP
Bromodomain-Containing Protein 4: A Druggable Target.
期刊论文
Current drug targets, 2019
作者:
Shi Yingying
;
Liu Jingwen
;
Zhao Yuanyuan
;
Cao Jiaoxian
;
Li Yiming
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Bromodomain-containing protein 4
coronary heart disease
natural products
pharmacology
small molecule inhibitors
synthetic compounds.
tumor
Small molecules as inhibitors of PCSK9: Current status and future challenges
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Shengtao Xu
;
Shanshan Luo
;
Zheying Zhu
;
Jinyi Xu
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/13
PCSK9
protein
Inhibitor
Small-molecule
LDL-C
Hypercholesterolemia
Natural
products
Patent
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