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复旦大学上海医学院 [14]
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浏览/检索结果:
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Crosstalk between CYP2E1 and PPAR alpha substrates and agonists modulate adipose browning and obesity
期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2224-2238
作者:
Zhang, Youbo
;
Yan, Tingting
;
Wang, Tianxia
;
Liu, Xiaoyan
;
Hamada, Keisuke
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/07/19
CYP2E1
PPAR alpha
FGF21
Metabolic enzyme
Nuclear receptor
Obesity
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Ren, Xiaoqian
;
Giesy, John P.
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/12/02
SCCPs
Mode of action
PPAR alpha
Luciferase assay
Molecular docking
Metabolomics
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury
期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:
Hu, Dan-Dan
;
Zhao, Qi
;
Cheng, Yan
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/03/26
liver injury
metabolomics
PPAR alpha
acylcarnitines
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate
期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
作者:
Hua, Huiying
;
Dai, Manyun
;
Luo, Yishuang
;
Lin, Hante
;
Xu, Gangming
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2018/12/18
PPAR alpha
FXR pathway
Alpha-naphthylisothiocyanate
Chronic cholestasis
PPAR alpha gene is a diagnostic and prognostic biomarker in clear cell renal cell carcinoma by integrated bioinformatics analysis
期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 10
作者:
Luo, Yongwen
;
Chen, Liang
;
Wang, Gang
;
Qian, Guofeng
;
Liu, Xuefeng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
PPAR alpha
clear cell renal cell carcinoma (ccRCC)
biomarkers
gene set enrichment analysis (GSEA)
nomogram
Beta-hydroxybutyric acid attenuates neuronal damage in epileptic mice
期刊论文
ACTA HISTOCHEMICA, 2019, 卷号: 121, 期号: 4, 页码: 455-459
作者:
Guo, Qinghui
;
Liu, Shangming
;
Wang, Shandan
;
Wu, Meiyan
;
Li, Zhaoxia
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/11
beta-Hydroxybutyric acid
Epilepsy
Apoptosis
Oxidative stress
AMPK
PPAR alpha
PPAR-gamma agonist pioglitazone protects against IL-17 induced intervertebral disc inflammation and degeneration via suppression of NF-kappa B signaling pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 卷号: 72, 页码: 138-147
作者:
Liu, Yi
;
Qu, Yuan
;
Liu, Lian
;
Zhao, Hua
;
Ma, Hecheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Interleukin-17
Intervertebral disc degeneration
PPAR-gamma
TNF-alpha
NF-kappa B pathway
Inflammatory
Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1 alpha signaling
期刊论文
2019, 卷号: 93, 期号: 6, 页码: 1543-1553
作者:
Ichihara, Sahoko
;
Li, Ping
;
Mise, Nathan
;
Suzuki, Yuka
;
Izuoka, Kiyora
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/01/03
AHR
Cardiac hypertrophy
Fibrosis
Angiotensin II
PPAR alpha
HIF-1 alpha
Vascular endothelial growth factor
A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters
期刊论文
2019, 卷号: 40, 期号: 7, 页码: 895-907
作者:
Ge, Mao-xu
;
Niu, Wei-xiao
;
Ren, Jin-feng
;
Cai, Shi-ying
;
Yu, Dong-ke
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
ASBT inhibitor
NAFLD
CYP7A1
AMPK alpha
PPAR alpha
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