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北京大学 [12]
复旦大学上海医学院 [5]
西安交通大学 [4]
中国医学科学院 北京... [4]
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期刊论文 [39]
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Ginkgolides B alleviates hypoxia-induced PC-12 cell injury by up-regulation of PLK1
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 115
作者:
Gao, Jian
;
Kang, Mingyang
;
Han, Yingying
;
Zhang, Tuo
;
Jin, Hui
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/05
Cerebral ischemia
Ginkgolides B
PC-12 cells
Polo-like kinase 1
PI3K/AKT pathway
MEK/ERK pathway
MicroRNA-505 suppresses gastric cancer cell proliferation and invasion by directly targeting Polo-like kinase-1
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12, 页码: 795-803
作者:
Dang, Sheng-Chun[1]
;
Wang, Fei[2]
;
Qian, Xiao-Bao[3]
;
Abdul, Malik[4]
;
Naseer, Qais-Ahmad[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
MicroRNA-505
EMT
polo-like kinase-1
gastric cancer
Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest
期刊论文
RESPIRATORY RESEARCH, 2018, 卷号: 19
作者:
Zhou, Jian
;
Chang, Meijia
;
Li, Jing
;
Fang, Tao
;
Hu, Jie
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Non-small cell lung cancer
Annexin A5
Gefitinib
Polo-like kinase 1
The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner
期刊论文
GLIA, 2018, 卷号: 66, 期号: 9
作者:
Jiang, Minqing
;
Rao, Rohit
;
Wang, Jincheng
;
Wang, Jiajia
;
Xu, Lingli
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
mTOR signaling
myelination
polo-like kinase
proliferation
Schwann cell
TSC
tumor suppressor
BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 52, 期号: 3, 页码: 804-814
作者:
Lian, Guodong
;
Li, Leping
;
Shi, Yulong
;
Jing, Changqing
;
Liu, Jinglei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
gastric cancer
polo-like kinase 1 inhibitor
cisplatin
protein pathway
array
synergistic
High LIN28A and PLK4 co-expression is associated with poor prognosis in epithelial ovarian cancer
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 期号: 6, 页码: 5327-5336
作者:
He, Yao[1]
;
Wang, Hui[2]
;
Yan, Meina[3]
;
Yang, Xinxin[4]
;
Shen, Rong[5]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/24
epithelial ovarian cancer
LIN28 homolog A
polo-like kinase 4
prognosis
co-expression
Survival analysis of genome-wide profiles coupled with Connectivity Map database mining to identify potential therapeutic targets for cholangiocarcinoma
期刊论文
ONCOLOGY REPORTS, 2018, 卷号: Vol.40 No.6, 页码: 3189-3198
作者:
Lin, Peng
;
Zhong, Xiao-Zhu
;
Wang, Xiao-Dong
;
Li, Jian-Jun
;
Zhao, Rui-Qi
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/26
cholangiocarcinoma
connectivity
map
molecular
docking
prognosis
polo-like
kinase
1
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma
期刊论文
2018, 卷号: 96, 期号: 8, 页码: 807-817
作者:
Liu, Ting-Ting
;
Yang, Kai-Xia
;
Yu, Jing
;
Cao, Ying-Ya
;
Ren, Jian-Song
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Esophageal cancer
Polo-like kinase 1
Mammalian/mechanistic target of rapamycin
BI 2536
Rapamycin
Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors
期刊论文
CANCER LETTERS, 2017, 卷号: 392
作者:
Zhang, Ming
;
Singh, Ratnakar
;
Peng, Shaohua
;
Mazumdar, Tuhina
;
Sambandam, Vaishnavi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Polo-like kinase 1
Head neck squamous cell carcinoma
WEE1
CHK1
AJUBA
The equilibrium of ubiquitination and deubiquitination at PLK1 regulates sister chromatid separation
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2017
Liu, Junjun
;
Zhang, Chuanmao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2017/12/03
Polo-like kinase 1
Mitosis
Usp16
Kinetochore
Cullin 3
E3 ligase
POLO-LIKE KINASES
KINETOCHORE-MICROTUBULE DYNAMICS
SPINDLE ASSEMBLY CHECKPOINT
PROPER CHROMOSOME SEGREGATION
CELL-DIVISION
BOX DOMAIN
PROTEIN
PHOSPHORYLATION
STABILITY
COMPLEX
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