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CORC

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Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han
收藏  |  浏览/下载：32/0  |  提交时间：2022/12/22
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial 期刊论文
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:  Liu, Jihong;  Yin, Rutie;  Wu, Lingying;  Zhu, Jianqing;  Lou, Ge
收藏  |  浏览/下载：38/0  |  提交时间：2022/05/05
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping
收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun
收藏  |  浏览/下载：42/0  |  提交时间：2021/04/21
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors 期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:  Li, Huiping;  Liu, Rongrui;  Shao, Bin;  Ran, Ran;  Song, Guohong
收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:  
收藏  |  浏览/下载：34/0  |  提交时间：2020/09/23
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells 期刊论文
CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740
作者:  Lu, Qin;  Zhang, Fang-Lin;  Lu, Da-Yun;  Shao, Zhi-Ming;  Li, Da-Qiang
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors 期刊论文
Journal of enzyme inhibition and medicinal chemistry, 2019, 卷号: 34, 页码: 150-162
作者:  Gao Cheng-Zhi[1];  Dong Wei[2];  Cui Zhi-Wen[3];  Yuan Qiong[4];  Hu Xia-Min[5]
收藏  |  浏览/下载：37/0  |  提交时间：2019/04/22
Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2019, 卷号: 34, 期号: 1
作者:  Gao, Cheng-Zhi;  Dong, Wei;  Cui, Zhi-Wen;  Yuan, Qiong;  Hu, Xia-Min
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/06
OlympiAD final overall survival and tolerability results: Olaparib versus chemotherapy treatment of physician's choice in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer 期刊论文
2019, 卷号: 30, 期号: 4, 页码: 558-566
作者:  Robson, M. E.;  Tung, N.;  Conte, P.;  Im, S-A;  Senkus, E.
收藏  |  浏览/下载：9/0  |  提交时间：2020/01/03

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