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Safety and Efficacy of D-1553 in Patients with KRAS G12C Mutated Non-Small Cell Lung Cancer: A Phase 1 Trial
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:
Lu, S.
;
Jian, H.
;
Zhang, Y.
;
Song, Z.
;
Zhao, Y.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Non-small cell lung cancer
KRAS G12C mutation
Small molecular inhibitor
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ion beam irradiation
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 卷号: 103, 页码: 1851-1864
作者:
Guo, Xiaopeng
;
Zhang, Miaomiao
;
Gao, Yue
;
Cao, Guozhen
;
Yang, Yang
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/04/02
Saccharomyces cerevisiae
Carbon ion beam irradiation
Respiration-deficient mutants
Genome-wide resequencing
Molecular mutation spectrum
Mitochondrial genome
A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ion beam irradiation
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 卷号: 103, 期号: 4, 页码: 1851-1864
作者:
Guo, Xiaopeng
;
Zhang, Miaomiao
;
Gao, Yue
;
Cao, Guozhen
;
Yang, Yang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/15
Saccharomyces cerevisiae
Carbon ion beam irradiation
Respiration-deficient mutants
Genome-wide resequencing
Molecular mutation spectrum
Mitochondrial genome
Great efficacy of afatinib on a patient with lung adenocarcinoma harboring uncommon EGFR delE709_T710insD mutations: a case report
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12, 页码: 7399-7404
作者:
An, Ning
;
Wang, Haoyi
;
Zhu, Hui
;
Yan, Weiwei
;
Jing, Wang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/11
non-small-cell lung cancer
epidermal growth factor receptor
molecular
targeted therapy
tyrosine kinase inhibitor
afatinib
EGFR rare
mutation
A genome-wide view of mutations in respiration-deficient mutants of Saccharomyces cerevisiae selected following carbon ion beam irradiation.
期刊论文
Applied microbiology and biotechnology, 2019
作者:
Xiaopeng Guo
;
Miaomiao Zhang
;
Yue Gao
;
Guozhen Cao
;
Yang Yang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/13
Carbon
ion
beam
irradiation
Genome-wide
resequencing
Mitochondrial
genome
Molecular
mutation
spectrum
Respiration-deficient
mutants
Saccharomyces
cerevisiae
Role of introduced surface cysteine of NADH oxidase from Lactobacillus rhamnosus
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 132, 页码: 150-156
作者:
Li, Fei-Long[1]
;
Tao, Qing-Lan[2]
;
Liu, Cai-Yun[3]
;
Gao, Jian[4]
;
Zhang, Ye-Wang[5]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/24
Cysteine
Oxidative stress
NADH oxidase
Surface mutation
Molecular docking
Combinatorial mutation on the beta-glycosidase specific to 7-beta-xylosyltaxanes and increasing the mutated enzyme production by engineering the recombinant yeast
期刊论文
2019, 卷号: 9, 期号: 3, 页码: 626-638
作者:
Chen, Jing-Jing
;
Liang, Xiao
;
Wang, Fen
;
Wen, Yan-Hua
;
Chen, Tian-Jiao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
beta-Glycosidases
Combinatorial mutation
Improved catalytic property
Molecular docking
Engineered Yeast
Taxol
Significance of the epidermal growth factor receptor mutation status and differences among molecular subgroups in surgically resected lung microinvasive adenocarcinoma
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 6, 页码: 7057-7067
作者:
Li, Ming
;
Li, Chuanying
;
Ke, Li
;
Zhan, Mali
;
Cheng, Min
收藏
  |  
浏览/下载:242/0
  |  
提交时间:2019/06/20
epidermal growth factor receptor
mutation
non-small cell lung cancer
microinvasive adenocarcinoma
molecular subgroup
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