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科研机构
山东大学 [4]
湖南大学 [3]
上海药物研究所 [2]
北京大学 [1]
南开大学 [1]
内容类型
期刊论文 [11]
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2019 [1]
2018 [3]
2015 [1]
2012 [3]
2009 [2]
2006 [1]
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Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.163, 页码: 428-442
作者:
Wenlong Li
;
Wen Shuai
;
Honghao Sun
;
Feijie Xu
;
Yi Bi
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/13
Quinoline
Indole
Microtubule
Tubulin
inhibitor
Colchicine
binding
site
Antitumor
The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018, 卷号: 1862, 期号: 5, 页码: 1134-1147
作者:
Wu, Xingkang
;
Li, Zhenyu
;
Shen, Yuemao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
CS1
Mitotic arrest
Spindle assembly checkpoint
Sister chromatid
resolution
Microtubule inhibitor
Histone phosphorylation
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site.
期刊论文
European journal of medicinal chemistry, 2018, 卷号: Vol.163, 页码: 428-442
作者:
Li Wenlong
;
Shuai Wen
;
Sun Honghao
;
Xu Feijie
;
Bi Yi
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/26
Antitumor
Colchicine
binding
site
Indole
Microtubule
Quinoline
Tubulin
inhibitor
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site
期刊论文
European Journal of Medicinal Chemistry, 2018
作者:
Wenlong Li
;
Wen Shuai
;
Honghao Sun
;
Feijie Xu
;
Yi Bi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
Quinoline
Indole
Microtubule
Tubulin
inhibitor
Colchicine
binding
site
Antitumor
Deacetyl-mycoepoxydiene, isolated from plant endophytic fungi Phomosis sp demonstrates anti-microtubule activity in MCF-7 cells
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2015, 卷号: 69, 页码: 82-89
作者:
Zhu, Shan-Shan
;
Zhang, Yu-Sheng
;
Sheng, Xie-Huang
;
Xu, Miao
;
Wu, Si-Si
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
Microtubule inhibitor
Cell cycle arrest
Apoptosis
Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity
期刊论文
细胞研究英文版, 2012
Wu, Qixi
;
He, Runsheng
;
Zhou, Haining
;
Yu, Albert C. H.
;
Zhang, Bo
;
Teng, Junlin
;
Chen, Jianguo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/13
Cep57
centrosome
spindle
cell cycle
SMALL-MOLECULE INHIBITOR
CENTROSOME INTEGRITY
MITOTIC SPINDLE
MICROTUBULE ATTACHMENT
CHROMOSOME SEGREGATION
RING COMPLEX
PROTEINS
DYNAMICS
LOCALIZATION
RECRUITMENT
Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents
期刊论文
Bioorganic and medicinal chemistry, 2012, 卷号: 20, 期号: 7, 页码: 2382-2391
作者:
Jiang,J.
;
Sun,B.
;
Wang,Y.-Y.
;
Cui,M.
;
Zhang,L.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
Anticancer
Bisbibenzyls
Derivatives
Microtubule inhibitor
Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G_2-M arrest and apoptosis in HeLa cells
期刊论文
Acta Pharmacologica Sinica, 2012, 卷号: 33, 期号: 3, 页码: 407
作者:
Ma Yiming
;
Zhou Yubo
;
Xie Chuanming
;
Chen Dongmei
;
Li Jia
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
ACTIVATED PROTEIN-KINASE
TUBULIN-BINDING AGENT
IN-VIVO
ANTIMICROBIAL ACTIVITY
ANTICANCER ACTIVITY
CYCLE ARREST
CANCER-CELLS
DERIVATIVES
INHIBITOR
RESISTANT
anticancer drug
6-chloro-4-(methoxyphenyl) coumarin
cell cycle arrest
microtubule depolymerization
apoptosis
Transformation of human liver L-O2 cells mediated by stable HBx transfection
期刊论文
Acta Pharmacologica Sinica, 2009, 卷号: Vol.30 No.8, 页码: 1153-1161
作者:
Zhang WY
;
Cai N
;
Ye LH
;
Zhang XD.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/27
Animals
Carcinoma, Hepatocellular/*genetics
Cell Line
Cell Proliferation
Cell Transformation, Neoplastic
Centrosome/pathology
Gene Expression Regulation, Neoplastic
Humans
Inhibitor of Apoptosis Proteins
Liver/*cytology
Liver Neoplasms/*genetics
Mice
Mice, Nude
Microtubule-Associated Proteins/genetics/metabolism
NF-kappa B/genetics/metabolism
NIH 3T3 Cells
Telomerase/metabolism
Trans-Activators/*genetics/metabolism
Transcription Factor AP-1/genetics/metabolism
Transfection
Marchantin C, a novel microtubule inhibitor from liverwort with anti-tumor activity both in vivo and in vitro
期刊论文
CANCER LETTERS, 2009, 卷号: 276, 期号: 2, 页码: 160-170
作者:
Shi, Yan-qiu
;
Zhu, Chang-jun
;
Yuan, Hui-qing
;
Li, Bo-qin
;
Gao, Jie
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/26
Marchantin C
Macrocyclic bisbibenzyl
Microtubule inhibitor
Cell cycle
arrest
Tumor cell apoptosis
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