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科研机构
中南大学 [4]
厦门大学 [1]
湖南中医药大学 [1]
内容类型
期刊论文 [5]
学位论文 [1]
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2017 [1]
2015 [1]
2013 [2]
2011 [2]
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中药枳壳及其吸收成分水合橙皮内酯抗抑郁促胃肠动力作用机理研究
学位论文
2017, 2016
柳进
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/06/20
枳壳
水合橙皮内酯
抗抑郁
促胃肠动力
脑肠肽
Fructus aurantii
Meranzin hydrate
Antidepressant
Prokinetic
Ghrelin
Traditional Chinese medicine Zhiqiao-Houpu herb-pair induce bidirectional effects on gastric motility in rats.
期刊论文
Journal of Ethnopharmacology, 2015, 卷号: 175, 页码: 444-450
作者:
Xiong, XinGui
;
Peng, WeiJun
;
Chen, Li
;
Liu, HaiTao
;
Huang, Wei*
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Gastric antral smooth muscle contractility
Gastric emptying
Herb-pair Zhiqiao-Houpu
Hesperidin (PubChem CID: 10621)
Honokiol (PubChem CID: 72303)
Magnolol (PubChem CID: 72300)
Meranzin Hydrate (PubChem CID: 5070783)
Naringin (PubChem CID: 442428)
Narirutin (PubChem CID: 442431)
Neohesperidin (PubChem CID: 442439)
Meranzin hydrate exhibits anti-depressive and prokinetic-like effects through regulation of the shared alpha 2-adrenoceptor in the brain-gut axis of rats in the forced swimming test
期刊论文
Neuropharmacology, 2013, 卷号: 67, 页码: 318-325
作者:
Xie, Ying
;
Huang, Xi*
;
Hu, Sui-yu
;
Qiu, Xin-jian
;
Zhang, Ying-jin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Depression
Gastrointestinal dysfunction
Meranzin hydrate
Common mechanism
Alpha 2-adrenoceptor
Ghrelin
Meranzin hydrate exhibits anti-depressive and prokinetic-like effects through regulation of the shared alpha 2-adrenoceptor in the brain-gut axis of rats in the forced swimming test
期刊论文
Neuropharmacology, 2013, 卷号: 67, 页码: 318-325
作者:
Xie, Ying
;
Huang, Xi*
;
Hu, Sui-yu
;
Qiu, Xin-jian
;
Zhang, Ying-jin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/27
Depression
Gastrointestinal dysfunction
Meranzin hydrate
Common mechanism
Alpha 2-adrenoceptor
Ghrelin
Meranzin Hydrate Induces Similar Effect to Fructus Aurantii on Intestinal Motility through Activation of H1 Histamine Receptors
期刊论文
Journal of Gastrointestinal Surgery, 2011, 卷号: 15, 期号: 1, 页码: 87-96
作者:
Huang, Wei
;
Huang, Xi*
;
Xing, Zhihua
;
Qiu, Xinjian
;
Wang, Yang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Meranzin hydrate
Intestinal motility
Jejunum
Fructus Aurantii
Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral administration of Chaihu-Shugan-San to patients with functional dyspepsia
期刊论文
Journal of Ethnopharmacology, 2011, 卷号: 137, 期号: 1, 页码: 205-213
作者:
Qiu, Xin-Jian
;
Huang, Xi*
;
Chen, Ze-Qi
;
Ren, Ping
;
Huang, Wei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
AUC(0–∞)
area under concentration–time curve from t = 0 to last time
CL/F
apparent clearance
Cmax
maximum plasma concentration
CSS
Chaihu-Shugan-San
C–t
concentration–time
FA
ferulic acid
FD
functional dyspepsia
GE
gastric emptying
HPLC
high performance liquid chromatography
HPMC
hydroxypropylmethyl cellulose
IS
internal standard
IT
intestinal transit
K10
apparent first-order elimination rate constant from the central compartment
K21 and K12
apparent first-order inter compartmental transfer rate constants
Ka
absorption constant
LLOQ
lower limit of quantification
MH
meranzin hydrate
MRM
multiple reaction monitoring
MRT
mean residence time
QC
quality control
RE
relative error
RSD
relative standard deviation
SMZ
sulfamethoxazole
T1/2α
distribution half-life
T1/2β
elimination half-life
TCM
traditional Chinese medicine
Tmax
time to reach peak concentration
UPLC
ultra performance liquid chromatography
UPLC-MS/MS
ultra performance liquid chromatography with tandem mass spectrometry
V1/F
volume of distribution
Meranzin hydrate
Ferulic acid
Chaihu-Shugan-San
Functional dyspepsia
Clinical Pharmacokinetic
Pharmacodynamic
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