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湖南农业大学 [5]
北京大学 [2]
武汉物理与数学研究所 [2]
湖南大学 [2]
清华大学 [1]
武汉大学 [1]
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期刊论文 [13]
发表日期
2018 [2]
2016 [1]
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2013 [1]
2012 [1]
2011 [3]
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波谱学 [1]
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Corrigendum: Mequindox Induced Genotoxicity and Carcinogenicity in Mice
期刊论文
Frontiers in Pharmacology, 2018, 卷号: Vol.9
作者:
Qianying Liu
;
Zhixin Lei
;
Qin Wu
;
Deyu Huang
;
Shuyu Xie
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/26
mequindox
quinoxaline
carcinogenicity
genotoxicity
KM
mice
The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats
期刊论文
Frontiers in Pharmacology, 2018, 卷号: Vol.9
作者:
Qianying Liu
;
Zhixin Lei
;
Qin Wu
;
Ihsan Awais
;
Muhammad A. B. Shabbir
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/26
reproductive
toxicity
teratogenicity
mequindox
Wistar
rats
developmental
toxicity
The critical role of oxidative stress in the toxicity and metabolism of quinoxaline 1,4-di-N-oxides in vitro and in vivo
期刊论文
Drug metabolism reviews, 2016, 卷号: 48, 期号: 2, 页码: 159-182
作者:
Wang, Xu
;
Martinez, Maria-Aranzazu
;
Cheng, Guyue
;
Liu, Zhaoying
;
Huang, Lingli
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
*Quinoxaline
*antioxidants
*carbadox
*cyadox
*mequindox
*olaquindox
*oxidative stress
*quinocetone
*reactive oxygen species
Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp
期刊论文
Food and Chemical Toxicology, 2014, 卷号: 69, 页码: 109-119
作者:
Li, Juan
;
Huang, Lingli
;
Wang, Xu
;
Pan, Yuanhu
;
Liu, Zhaoying
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/23
QCT (Q0)
quinocetone
Q1
1-desoxyquinocetone
Q2
dideoxyquinocetone
Q3
carbonyl-reduced metabolites of 1-deoxyquinocetone
Q4
carbonyl- and double-bond-reduced metabolites of 1-deoxyquinocetone
Q5
carbonyl-reduced metabolites of dideoxyquinocetone
Q6
phenyl ring hydroxylation metabolites of carbonyl-reduced quinocetone
Q7
carbonyl-reduced quinocetone
Q8
double-bond-reduced metabolite of 4-deoxyquinocetone
Q9
phenyl ring hydroxylation metabolites of quinocetone
OLA
olaquindox
CBX
carbadox
QdNOs
quinoxaline 1,4-dioxides
MQCA
3-methylquinoxaline-2-carboxylic acid
MEQ
mequindox
QCA
quinoxalie-2-carboxylic acid
CYA
cyadox
JECFA
Joint FAO/WHO Expert Committee on Food Additives
VICH
International Cooperation on Harmonization of Technical Requirements for the Registration of Veterinary Medicinal Products
LSC
liquid scintillation counting
EIC
extracted ion chromatograms
CYP
cytochrome P450 enzyme
CBR
carbonyl reductase
H2O2
hydrogen peroxide
ROS
reactive oxygen species
Quinocetone
Radioactivity isotope tracing
Disposition
Metabolism
Excretion
Toxicology
The Metabolism of Carbadox, Olaquindox, Mequindox, Quinocetone and Cyadox: An Overview
期刊论文
Medicinal Chemistry, 2013, 卷号: 9, 期号: 8, 页码: 1017-1027
作者:
Liu, Zhao-Ying
;
Sun, Zhi-Liang*
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
Carbadox
Cyadox
Mequindox
Metabolism
Olaquindox
Quinocetone
Systems Responses of Rats to Mequindox Revealed by Metabolic and Transcriptomic Profiling
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2012, 卷号: 11, 期号: 9, 页码: 4712-4721
作者:
Zhao, Xiu-Ju
;
Hao, Fuhua
;
Huang, Chongyang
;
Rantalainen, Mattias
;
Lei, Hehua
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/06/25
mequindox
metabonomics
NMR
pattern recognition
rat
transcriptomics
Dynamic Metabolic Response of Mice to Acute Mequindox Exposure
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2011, 卷号: 10, 期号: 11, 页码: 5183-5190
作者:
Zhao, Xiu-Ju
;
Huang, Chongyang
;
Lei, Hehua
;
Nie, Xiu
;
Tang, Huiru
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/06/25
NMR
pattern recognition
metabonomics
mequindox
dose effect
time effect
mice
Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats
期刊论文
Toxicology and Applied Pharmacology, 2011, 卷号: 252, 期号: 3, 页码: 281-288
作者:
Ihsan, Awais
;
Wang, Xu
;
Liu, Zhaoying
;
Wang, Yulian
;
Huang, Xianju
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
AR
androgen receptor
CBX
carbadox
CNS,
central nervous system
FSH
follicle stimulating hormone
GSH
reduced glutathione
H2O2
hydrogen peroxide
MDA
malondialdehyde
MEQ
mequindox
LH
lutinizing hormone
LPO
lipid peroxidation
OLA
olaquindox
QdNOs
quinoxaline 1, 4-dioxides
ROS
reactive oxygen species
SOD
superoxide dismutase
8-OHdG
8-hydroxydeoxyguanosine
StAR
steroidogenic acute regulatory protein
DNA damage
Mequindox
Oxidative stress
Quinoxaline
Rats
Testis
Testosterone
8-hydroxydeoxyguanosine (8-OHdG)
Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox
期刊论文
Toxicology, 2011, 卷号: 280, 期号: 3, 页码: 126-134
作者:
Wang, Xu
;
Huang, Xian-Ju
;
Ihsan, Awais
;
Liu, Zhao-Ying
;
Huang, Ling-Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
CIS
cytokine-induced SH2 protein
EICs
extracted ion chromatograms
IL-6
interleukin 6
JAK
Janus kinase
LC/MS–ITTOF
high-performance liquid chromatography combined with hybrid ion trap/time-of-flight
MDA
malondialdehyde
MEQ
mequindox
ROS
reactive oxygen species
SOCS
suppressors of cytokine signaling
SOD
superoxide dismutase
RT-PCR
real-time reverse transcriptional polymerase chain reaction
STAT
signal transducer and activator of transcription
TNF-α
tumor necrosis factor alpha
Mequindox
JAK/STAT
SOCS
NADPH
Oxidative stress
Inflammatory cytokines
乙酰甲喹中共存物的气相色谱-质谱分析
期刊论文
2010, 2010
杨成对
;
宋莉晖
;
YANG Cheng-dui
;
SONG Li-hui
收藏
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浏览/下载:2/0
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