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科研机构
北京大学 [2]
上海药物研究所 [2]
高能物理研究所 [2]
山东大学 [2]
清华大学 [1]
兰州大学 [1]
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期刊论文 [17]
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2019 [1]
2018 [1]
2017 [6]
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Discovery of coumarin Mannich base derivatives as multifunctional agents against monoamine oxidase B and neuroinflammation for the treatment of Parkinson's disease
期刊论文
2019, 卷号: 173, 页码: 203-212
作者:
Tao, Deng
;
Wang, Yue
;
Bao, Xiu-Qi
;
Yang, Bei-Bei
;
Gao, Fan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Parkinson's disease
Multifunctional compounds
Coumarin Mannich base
MAO-B inhibitors
Anti-inflammatory effect
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 33-47
作者:
Xu, Yi-xiang
;
Wang, Huan
;
Li, Xiao-kang
;
Dong, Sheng-nan
;
Liu, Wen-wen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Multifunctional agents
AChE inhibitors
MAO-B inhibitors
Metal chelating agents
Alzheimer's disease
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
Iron modulates the activity of monoamine oxidase b in sh-sy5y cells
期刊论文
Biometals, 2017, 卷号: 30, 期号: 4, 页码: 599-607
作者:
Lu, Huiru
;
Chen, Jun
;
Huang, Hui
;
Zhou, Mengxue
;
Zhu, Qing
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  |  
浏览/下载:132/0
  |  
提交时间:2019/04/23
Iron
Mao-b
Fluorescence probe
Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells
期刊论文
BIOMETALS, 2017, 卷号: 30, 期号: 4, 页码: 599-607
作者:
Chen J(陈俊)
;
Hu, Y
;
Chai, ZF
;
Yao, SQ
;
Zhu, Q
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2019/08/27
Iron
MAO-B
Fluorescence probe
Multi-Target Screening and Experimental Validation of Natural Products from Selaginella Plants against Alzheimer's Disease.
期刊论文
Frontiers in pharmacology, 2017, 卷号: 8, 期号: AUG, 页码: 539
作者:
Deng, Yin-Hua
;
Wang, Ning-Ning
;
Zou, Zhen-Xing
;
Zhang, Lin
;
Xu, Kang-Ping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Alzheimer
BACE1
MAO-B
Selaginella plants
multi-target SAR
multi-target screening
Synthesis, Crystal Structures, Molecular Docking and MAO-B Inhibitory Activity of Transition Metal Complexes Derived from 2-(4-(Pyridin-2-yl)piperazin-1-yl)acetic Acid
期刊论文
ACTA CHIMICA SLOVENICA, 2017, 卷号: 64, 期号: 4, 页码: 825-831
作者:
Ren, Yan-Jie
;
Zhu, Jin-Long
;
Zhang, Li-Xin
;
Xu, Yin-Xiang
;
Qian, Shao-Song
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/12
Metal complexes
Crystal Structure
MAO-B inhibitor
Molecular Docking
Multi-Target Screening and Experimental Validation of Natural Products from Selaginella Plants against Alzheimer's Disease.
期刊论文
Frontiers in pharmacology, 2017, 卷号: 8, 期号: AUG, 页码: 539
作者:
Deng, Yin-Hua
;
Wang, Ning-Ning
;
Zou, Zhen-Xing
;
Zhang, Lin
;
Xu, Kang-Ping
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/28
Alzheimer
BACE1
MAO-B
Selaginella plants
multi-target SAR
multi-target screening
Inhibitive activities detection of monoamine oxidases (MAO) A and B inhibitors in human liver MAO incubations by UPLC-ESI-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 卷号: 115
作者:
Jiang, Bo
;
Li, Shuping
;
Liu, Wei
;
Yang, Yadi
;
Chen, Wenxia
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
MAO-A
MAO-B
5-HIAA
PAA
Inhibitor
UPLC-ESI MS/MS
Association between monoamine oxidase gene polymorphisms and smoking behavior: A meta-analysis
期刊论文
DRUG AND ALCOHOL DEPENDENCE, 2015, 卷号: 153, 页码: 350-354
作者:
Yang, Xiaorong
;
Chen, Hui
;
Li, Suyun
;
Wang, Qiang
;
Pan, Lulu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
Monoamine oxidase gene
Smoking behavior
Polymorphism
Meta-analysis
MAO-A
MAO-B
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