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科研机构
北京大学 [11]
上海药物研究所 [3]
清华大学 [2]
内容类型
期刊论文 [16]
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2011 [1]
2010 [2]
2009 [2]
2008 [2]
2006 [4]
2005 [3]
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Biochemist... [2]
Virology [1]
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H-1, C-13 and N-15 resonance assignments of SARS-CoV main protease N-terminal domain
期刊论文
biomolecular nmr assignments, 2011
Zhang, Shengnan
;
Zhong, Nan
;
Ren, Xiaobai
;
Jin, Changwen
;
Xia, Bin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/11/10
SARS-CoV
Main protease
N-terminal domain
NMR
ACUTE RESPIRATORY SYNDROME
SYNDROME CORONAVIRUS
PROTEINASE
DIMER
FORM
C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer
期刊论文
2010, 2010
Zhong, Nan
;
Zhang, Shengnan
;
Xue, Fei
;
Kang, Xue
;
Zou, Peng
;
Chen, Jiaxuan
;
Liang, Chao
;
Rao, Zihe
;
Jin, Changwen
;
Lou, Zhiyong
;
Xia, Bin
收藏
  |  
浏览/下载:23/0
The search for a structural basis for therapeutic intervention against the SARS coronavirus
期刊论文
2010, 2010
Mark, Bartlam
;
Xue, Xiaoyu
;
Rao, Zihe
收藏
  |  
浏览/下载:4/0
C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer
期刊论文
蛋白质科学, 2009
Zhong, Nan
;
Zhang, Shengnan
;
Xue, Fei
;
Kang, Xue
;
Zou, Peng
;
Chen, Jiaxuan
;
Liang, Chao
;
Rao, Zihe
;
Jin, Changwen
;
Lou, Zhiyong
;
Xia, Bin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
SARS
main protease
domain-swapping
dimerization
C-terminal domain
ACUTE RESPIRATORY SYNDROME
TORSION ANGLE DYNAMICS
CHEMICAL-SHIFT INDEX
MACROMOLECULAR STRUCTURES
SYNDROME CORONAVIRUS
SECONDARY STRUCTURE
PROTEINASE
ASSIGNMENT
SOFTWARE
REVEALS
Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase
期刊论文
current pharmaceutical design, 2006
Lai, Luhua
;
Han, Xiaofeng
;
Chen, Hao
;
Wei, Ping
;
Huang, Changkang
;
Liu, Shiyong
;
Fan, Keqiang
;
Zhou, Lu
;
Liu, Zhenming
;
Pei, Jianfeng
;
Liu, Ying
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/13
SARS 3C-like proteinase
quaternary structure
enzyme catalytic mechanism
substrate selectivity
inhibitor design
ACUTE RESPIRATORY SYNDROME
RHINOVIRUS 3C PROTEASE
CORONAVIRUS MAIN PROTEINASE
IMIDAZOLIUM ION-PAIR
ACTIVE-SITE
2-PYRIDONE-CONTAINING PEPTIDOMIMETICS
ANALYTICAL ULTRACENTRIFUGATION
IRREVERSIBLE INHIBITORS
BIOLOGICAL EVALUATION
GENOME SEQUENCE
Only one protomer is active in the dimer of SARS 3C-like proteinase
期刊论文
journal of biological chemistry, 2006
Chen, Hao
;
Wei, Ping
;
Huang, Changkang
;
Tan, Lei
;
Liu, Ying
;
Lai, Luhua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/14
ACUTE RESPIRATORY SYNDROME
MOLECULAR-DYNAMICS SIMULATIONS
CORONAVIRUS MAIN PROTEINASE
CRYSTAL-STRUCTURES
PROTEASE
DESIGN
DIMERIZATION
INHIBITORS
MECHANISM
REVEALS
The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase
期刊论文
生物化学与生物物理学研究通讯, 2006
Wei, P
;
Fan, KQ
;
Chen, H
;
Ma, L
;
Huang, CK
;
Tan, L
;
Xi, D
;
Li, CM
;
Liu, Y
;
Cao, AN
;
Lai, LH
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
SARS coronavirus
3C-like proteinase
mutational study
N-terminal peptide
dimerization inhibitor
peptide inhibitor
Zhang-Poorman plot
ACUTE-RESPIRATORY-SYNDROME
LINKED INTERFACIAL PEPTIDES
SMALL-MOLECULE INHIBITORS
HIV-1 PROTEASE
MAIN PROTEASE
ANALYTICAL ULTRACENTRIFUGATION
HUMAN-IMMUNODEFICIENCY
CRYSTAL-STRUCTURES
VIRUS PROTEASES
3CL PROTEASE
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