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厦门大学 [18]
复旦大学上海医学院 [16]
上海药物研究所 [13]
四川大学 [13]
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期刊论文 [168]
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浏览/检索结果:
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Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15
作者:
Liu, Huan
;
Sun, Zhaolin
;
Tian, Xiaoting
;
Feng, Qin
;
Guo, Ziqiong
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
HPLC-Q-TOF
intestinal bacteria
liver
metabolism
Qushi Huayu Fang
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:
Wang, Fang
;
Yang, Xiaoyan
;
Lu, Yanting
;
Li, Zhenghui
;
Xu, Yuhui
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2019/09/10
glucose metabolism
liver kinase B1 (LKB1)
AMP-activated kinase (AMPK)
glucose transporter type 4 (GLUT4)
fungi
Basidiomycete
diabetes
energy sensing
glucose homeostasis
sesquiterpene
Transcriptome analysis of grass carp provides insights into disease-related genes and novel regulation pattern of bile acid feedback in response to lithocholic acid
期刊论文
AQUACULTURE, 2019, 卷号: 500, 页码: 613-621
作者:
Wang, Guitang
;
Li, Ming
;
Zou, Hong
;
Li, Wenxiang
;
Shi, Mijuan
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/03/05
Bile acid
Gut microbiota
Lipid metabolism
Nonalcoholic fatty liver disease
Freshwater fish
Global microRNA and isomiR expression associated with liver metabolism is induced by organophosphorus flame retardant exposure in male Chinese rare minnow (Gobiocypris rarus)
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 649, 页码: 829-838
作者:
Hong, Xiangsheng
;
Chen, Rui
;
Yuan, Lilai
;
Zha, Jinmiao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/10/23
Organophosphorus flame retardants (OPFRs)
microRNA
isomiR
Bioinformatics
Liver metabolism
Chinese rare minnow (Gobiocypris rants)
Establishment of rat liver microsome-hydrogel system for in vitro phase II metabolism and its application to study pharmacological effects of UGT substrates
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2019, 卷号: 34, 期号: 2
作者:
Zhang, Zhe
;
Ma, Guo
;
Xue, Caifu
;
Sun, Hong
;
Wang, Ziteng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
UGT
Phase II metabolism
FAB hydrogel
Liver microsome
Baicalein
Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease
期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10
作者:
Zhang, Gansheng
;
Shi, Dongmei
;
Chen, Jie
;
Wang, Jiaofeng
;
Yao, Jianfeng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
circadian rhythm
circadian clock
non-alcoholic fatty liver disease (NAFLD)
circadian clock gene
metabolism
Hypoxic Training in Obese Mice Improves Metabolic Disorder
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2019, 卷号: 10
作者:
Huang, Yiru
;
Wang, Ru
;
Guo, Shanshan
;
Lian, Haili
;
Yang, Qin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/05
hypoxic training
obesity
metabolomics
liver
metabolism
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
期刊论文
Cell metabolism, 2019
作者:
Adebayo Michael Adeola O
;
Ko Sungjin
;
Tao Junyan
;
Moghe Akshata
;
Yang Hong
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/11/19
precision therapy
metabolic zonation
liver tumor
tumor metabolism
hepatocellular cancer
mTOR
Wnt
glutamine synthetase
beta-catenin
personalized medicine
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