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浏览/检索结果:
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23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
2324dihydrocucurbitacinbpromoteslipidclearancebydualtranscriptionalregulationofldlrandpcsk9
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 327
作者:
Li Huihui
;
Li Jun
;
Zhang Xianjing
;
Li Jiaomeng
;
Xi Cong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
23
24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1α
SREBP2
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Lipid-altering Efficacy of Ezetimibe/Simvastatin Compared with Rosuvastatin in Hypercholesterolaemic Patients: A Meta-Analysis
期刊论文
INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2019, 卷号: 15, 期号: 2
作者:
Hu, Wanying
;
Xia, Nan
;
Liu, Yongming
;
Zhao, Wei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Hypercholesterolemia
ezetimibe/simvastatin
rosuvastatin
low-density lipoprotein cholesterol
lipid-lowering
lipid-altering
Impact of hyperlipidemia as a coexisting factor on the prognosis of idiopathic sudden sensorineural hearing loss: A propensity score matching analysis
期刊论文
Clinical Otolaryngology, 2019
作者:
Chen C.
;
Wang M.
;
Wang H.
;
Xiong W.
;
Dai Q.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
hyperlipidezmia
lipid-lowering therapy
propensity score
sudden hearing loss
treatment outcome
Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes: a systematic review and meta-analysis
期刊论文
2019, 卷号: 105, 期号: 15, 页码: 1149-1159
作者:
Du, Heyue
;
Li, Xiaodan
;
Su, Na
;
Li, Ling
;
Hao, Xiaoting
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
cardiovascular disease
low-density lipoprotein cholesterol
lipid-lowering drugs
proprotein convertase subtilisin
kexin type 9 inhibitors
systematic review
Synthesis and In Vitro Evaluation of Caffeoylquinic Acid Derivatives as Potential Hypolipidemic Agents
期刊论文
2019, 卷号: 24, 期号: 5
作者:
Tian, Yu
;
Cao, Xiao-Xue
;
Shang, Hai
;
Wu, Chong-Ming
;
Zhang, Xi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
caffeoylquinic acids
chlorogenic acid
derivatives
lipid-lowering effects
oleic acid-elicited
HepG2 cells
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Proteomics analysis reveals a potential new target protein for the lipid-lowering effect of Berberine8998
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1473-1482
作者:
Yu, Cheng-yin
;
Liu, Gang-yi
;
Liu, Xiao-hui
;
Gui, Yu-zhou
;
Liu, Hai-ming
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Salvifarinin A, a neo-clerodane diterpenoid with a 6/5/7 tricyclic skeleton from Salvia farinacea
期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 32, 页码: 3065-3068
作者:
Fan, Min
;
Chen, Xue-Jiao
;
Wu, Xing-De
;
Shao, Li-Dong
;
Ji, Xu
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2018/09/17
Neo-clerodane Diterpenoids
Salvia Farinacea
Lipid-lowering Activity
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