BP  Bipolar disorder  CA  Cornu ammonis  CNS  Central nervous system  CPP  3-(2-carboxypiperazin-4-yl) propyl-1-phosphonic acid  CT  Carboxyterminal  DG  Dentate gyrus  DGCs  Dentate granule cells  DISC  Disrupted-in-schizophrenia 1  Dixdc1  Dix domain containing 1  FEZ1  Elongation Protein Zeta-1  Fz  Frizzled  GABA  γ-aminobutyric acid  Grb2  Growth factor receptor bound protein 2  GSK3β  Glycogen synthase kinase 3β  KCC2  K+–Cl− co-transporter 2  kDa  kilodalton  KIF5B  Kinesin family members 5B  LEF/TCF  Lymphoid enhancer factor/T cell factor  LIS1  Lissencephaly-1  LRP5/6  Lipoprotein receptor-related protein 5/6  MDD  Major depressive disorder  MK-801  (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]c-cyclohepten-5-10-imine hydrogen maleate  MW  Molecular weight  NDEL1  Nuclear distribution gene E-like homolog 1  NKCC1  Na+-K+-Cl− co-transporter1  NLS  Nuclear localization signal  NMDA-R  N-methyl-d-aspartate-type glutamate receptor  d  NSCs  Neural stem cells  NT  Unique amino  NT-3  Neutrophins-3  OB  Olfactory bulbs  PTEN  Phosphatase and tensin homolog deleted on chromosome ten  RNAi  RNA interference  RYK  Related to tyrosine kinase  SGZ  Subgranular zone  shRNA  Short hairpin RNA  siRNA  Small interference RNA  SVZ  Subventricular zone  SZ  Schizophrenia  DISC1  Signaling pathway  Neurogenesis  DG  Hippocampus  

经典wnt信号通路  DKK蛋白  Kremen蛋白  LRP5/6蛋白  药物筛选