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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载:43/0  |  提交时间:2022/01/04
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:  Xu, Biao;  Wang, Zhi-Peng;  Liu, Qingwang;  Yang, Xiaohong;  Li, Xuemin
收藏  |  浏览/下载:28/0  |  提交时间:2021/05/17
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:  Xu, Biao;  Wang, Zhi-Peng;  Liu, Qingwang;  Yang, Xiaohong;  Li, Xuemin
收藏  |  浏览/下载:27/0  |  提交时间:2021/04/26
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载:49/0  |  提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun
收藏  |  浏览/下载:35/0  |  提交时间:2021/05/24
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice 期刊论文
PSYCHOPHARMACOLOGY, 2019, 卷号: 236, 期号: 11, 页码: 3301-3315
作者:  Zhang, Sha-Sha;  Tian, Yu-Hua;  Jin, Song-Jun;  Wang, Wen-Cheng;  Zhao, Jing-Xin
收藏  |  浏览/下载:36/0  |  提交时间:2020/09/21
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Identification of new NIK inhibitors by discriminatory analysis-based molecular docking and biological evaluation 期刊论文
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 7, 页码: 9
作者:  Cheng, Gang;  Mei, Xiao-Bing;  Yan, You-You;  Chen, Jing;  Zhang, Bo
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
A Convenient, Rapid, Sensitive, and Reliable Spectrophotometric Assay for Adenylate Kinase Activity. 期刊论文
Molecules (Basel, Switzerland), 2019, 卷号: Vol.24 No.4
作者:  Kai Song;  Yejing Wang;  Yu Li;  Chaoxiang Ding;  Rui Cai
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/17
Inhibition of Abl or Src tyrosine kinase decreased porcine circovirus type 2 production in PK15 cells. 期刊论文
Research in veterinary science, 2019, 卷号: 124, 页码: 1-9
作者:  Zhang, Jiaxin;  Lei, Xinnuo;  Wang, Dongliang;  Jiang, Yifan;  Zhan, Yang
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/23


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