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北京大学 [28]
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期刊论文 [97]
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Astragaloside IV ameliorates high glucose-induced renal tubular epithelial-mesenchymal transition by blocking mTORC1/p70S6K signaling in HK-2 cells
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: 43, 期号: 2
作者:
Chen, Xiao
;
Yang, Yang
;
Liu, Chenxu
;
Chen, Zhigao
;
Wang, Dongdong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
astragaloside IV
renal tubular
epithelial-mesenchymal transition
mammalian target of rapamycin complex 1
ribosomal protein S6 kinase-1 signaling
EZH2 inhibition suppresses bladder cancer cell growth and metastasis via the JAK2/STAT3 signaling pathway
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 1
作者:
Chen, Zhiyuan
;
Du, Yang
;
Liu, Xiuheng
;
Chen, Hui
;
Weng, Xiaodong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
bladder cancer
enhancer of zeste 2 polycomb repressive complex 2 subunit
janus kinase 2
signal transducer and activator of transcription 3
Astragaloside IV ameliorates high glucose-induced renal tubular epithelial-mesenchymal transition by blocking mTORC1/p70S6K signaling in HK-2 cells
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: Vol.43 No.2, 页码: 709-716
作者:
Chen, Xiao
;
Yang, Yang
;
Liu, Chenxu
;
Chen, Zhigao
;
Wang, Dongdong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/17
astragaloside IV
renal tubular
epithelial-mesenchymal transition
mammalian target of rapamycin complex 1
ribosomal protein S6 kinase-1 signaling
Mitochondrial Sirtuin 4 Resolves Immune Tolerance in Monocytes by Rebalancing Glycolysis and Glucose Oxidation Homeostasis
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9
作者:
Tao, Jie
;
Zhang, Jingpu
;
Ling, Yun
;
McCall, Charles E.
;
Liu, Tie Fu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
monocytes/macrophages
acute inflammatory resolution
glucose metabolic homeostasis
sirtuin 4
pyruvate dehydrogenase complex
pyruvate dehydrogenase kinase
Kinome Expansion in the Fusarium oxysporum Species Complex Driven by Accessory Chromosomes
期刊论文
MSPHERE, 2018, 卷号: 3
作者:
DeIulio, Gregory A.
;
Guo, Li
;
Zhang, Yong
;
Goldberg, Jonathan M.
;
Kistler, H. Corby
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/11/19
Fusarium oxysporum species complex
accessory chromosome
TOR kinase
histidine kinase
kinome
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
GSK-3 beta/mTORC1 Couples Synaptogenesis and Axonal Repair to Reduce Hypoxia Ischemia-Mediated Brain Injury in Neonatal Rats
期刊论文
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2018, 卷号: Vol.77 No.5, 页码: 383-394
作者:
Xiong, T
;
Qu, Y
;
Wang, HQ
;
Chen, HJ
;
Zhu, JH
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/28
Axons
Glycogen synthase kinase 3 beta (GSK-3 beta)
Hypoxia-ischemia
Mammalian target of rapamycin complex-1
Synapses
Lithium promotes the production of reactive oxygen species via GSK-3 beta/TSC2/TOR signaling in the gill of zebrafish (Danio rerio)
期刊论文
CHEMOSPHERE, 2018, 卷号: 195, 页码: 854-863
作者:
Liu, Dongwu
;
Gao, Lili
;
Zhang, Zhuangzhuang
;
Tao, Shiyi
;
Pang, Qiuxiang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
Lithium
Glycogen synthase kinase-3 beta
Tuberous sclerosis complex 2
Target of rapamycin
Reactive oxygen species
Danio rerio
AMP-activated protein kinase protects against necroptosis via regulation of Keap1-PGAM5 complex
期刊论文
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2018, 卷号: 259, 页码: 153-162
作者:
Wang, Yi-Shu[1]
;
Yu, Peng[2]
;
Wang, Yong[3]
;
Zhang, Jing[4]
;
Hang, Wei[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/24
AMP-activated protein kinase (AMPK)
Necroptosis
Keap1-PGAM5 complex
Metformin
Ischemia and reperfusion injury
Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway
期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2017, 卷号: 15, 期号: 8
作者:
Cheng, Z.
;
Gao, W.
;
Fan, X.
;
Chen, X.
;
Mei, H.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
casein kinase II
extracellular signal-regulated kinase 5
platelet activation
platelet glycoprotein GPIb-IX complex
PTEN
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