CORC

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CORC

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3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:  Liu, Man;  Xiao, Cheng-qian;  Sun, Ming-wei;  Tan, Min-jia;  Hu, Li-hong
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2 V617F against myeloproliferative neoplasms 期刊论文
Journal of Experimental and Clinical Cancer Research, 2019, 卷号: 38, 期号: 1
作者:  Hu M.;  Xu C.;  Yang C.;  Zuo H.;  Chen C.
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/11
Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors. 期刊论文
Bioorganic & medicinal chemistry, 2019, 卷号: 27, 期号: 12, 页码: 2592-2597
作者:  Wang, Yazhou*;  Huang, Wei*;  Xin, Minhang;  Chen, Pan;  Gui, Li
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/23
Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2(V617F) against myeloproliferative neoplasms 期刊论文
2019, 卷号: 38, 期号: 1, 页码: 49
作者:  Hu, Min;  Xu, Chengbo;  Yang, Chao;  Zuo, Hongli;  Chen, Chengjuan
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03
Discovery of novel selective Janus kinase 2 (JAK2) inhibitors bearing a 1H-pyrazolo[3,4-d]pyrimidin-4-amino scaffold 期刊论文
2019, 卷号: 27, 期号: 8, 页码: 1562-1576
作者:  Yin, Yuan;  Chen, Cheng-Juan;  Yu, Ru-Nan;  Shu, Lei;  Zhang, Tian-Tai
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03
3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578
作者:  Shan Hui;  Yao Sheng;  Ye Yang;  Yu Qiang
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu
收藏  |  浏览/下载：16/0  |  提交时间：2020/12/24
High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 6, 页码: 889-899
作者:  Yuliantie, Elita;  Dai, Xinchuan;  Yang, Dehua;  Crack, Peter J.;  Wang, Ming-Wei
收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08
Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 6
作者:  Liu, Man;  Xiao, Chengqian;  Sun, Mingwei
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08

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