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复旦大学上海医学院 [9]
上海药物研究所 [8]
昆明植物研究所 [8]
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Rhodium-Catalyzed C-H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2021, 页码: 7
作者:
Li, Yuan
;
Fang, Feifei
;
Zhou, Jianhui
;
Li, Jiyuan
;
Wang, Run
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Isoquinoline N-oxides
beta-hydroxy elimination
Rhodium
Secondary propargyl alcohols
Preparative separation of isoquinoline alkaloids from Corydalis impatiens using middle chromatogram isolated gel column coupled with positively charged reversed-phase liquid chromatography
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2020, 卷号: 43, 期号: 13
作者:
Wang, Qi
;
Chen, Wenjie
;
Wang, Qilan
;
Tao, Yanduo
;
Yu, Ruitao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/11/25
isoquinoline alkaloids
preparative separation
positive charge
traditional Tibetan medicine
Organo-Catalyzed Asymmetric Amination of 4-Arylisoquinoline-1,3(2H,4H)-dione Derivatives in the Construction of Quaternary Stereocenters
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 页码: 6
作者:
Cheng, Cheng
;
Li, Ying-Xian
;
Zhang, Ji-Quan
;
Zhao, Yong-Long
;
Zhang, Lin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Isoquinoline-1,3(2H,4H)-dione
Amination reaction
Asymmetric catalysis
Bifunctional catalyst
Chemical constituents from Thalictrum delavayi and their chemotaxonomic significance
期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2019, 卷号: 85
作者:
Yin, Tianpeng
;
Wang, Min
;
Ding, Zongbao
;
Deng, Liang
;
Li, Wei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/04
Thalictrum delavayi Franch.
Ranunculaceae
Isoquinoline alkaloids
Megastigmanes
Chemotaxonomy
Preparative separation of isoquinoline alkaloids from Corydalis impatiens using a middle-pressure chromatogram isolated gel column coupled with two-dimensional liquid chromatography
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2019, 卷号: 42, 期号: 20
作者:
Pan, Guoqing
;
Shen, Jianwei
;
Ma, Yuhua
;
He, Yanfeng
;
Bao, Yi
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/11/26
Corydalis impatiens
isoquinoline alkaloids
preparative separation
two-dimensional liquid chromatography
Cholinesterase inhibitory isoquinoline alkaloids from Corydalis mucronifera
期刊论文
2019, 卷号: Vol.159, 页码: 199-207
作者:
Jun Zhang
;
Chen Zhang
;
Fu-Chun Xu
;
Quesheng
;
Qing-Ying Zhang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/15
Corydalis
mucronifera
Maxim.
Isoquinoline
alkaloids
Cholinesterase
inhibitory
activity
Determination of berberine-upregulated endogenous short-chain fatty acids through derivatization by 2-bromoacetophenone
期刊论文
2019, 卷号: 411, 期号: 14, 页码: 3191-3207
作者:
Ma, Shu-Rong
;
Tong, Qian
;
Zhao, Zhen-Xiong
;
Cong, Lin
;
Yu, Jin-Bo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Derivatization
LC-MS
MS
Butyrate
Berberine
Isoquinoline alkaloids
2-Bromoacetophenone
differentstructuresofberberineandfiveotherprotoberberinealkaloidsthataffectpglycoproteinmediatedeffluxcapacity
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 1, 页码: 133
作者:
Zhang Yiting
;
Yu Yuqi
;
Yan Xiaoxia
;
Wang Wenjie
;
Tian Xiaoting
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
ISOQUINOLINE ALKALOIDS
DRUG-PERMEABILITY
ESCHERICHIA-COLI
ATP HYDROLYSIS
IN-VITRO
BINDING
ABSORPTION
TRANSPORT
PHARMACOKINETICS
CACO-2
P-glycoprotein
protoberberine alkaloid
berberine
binding affinity
efflux
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Development of an HPLC-DAD method for the determination of five alkaloids in Stephania yunnanensis Lo and in rat plasma after oral dose of Stephania yunnanensis Lo extracts
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2018, 卷号: 32, 期号: 10, 页码: 7
作者:
Xin, Aiyi
;
Zhang, Yaming
;
Zhang, Yanxia
;
Di, Duolong
;
Liu, Junxi
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/10/09
HPLC-DAD method
isoquinoline alkaloids
liquid-liquid extraction
quantitative determination
Stephania yunnanensis Lo
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