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复旦大学上海医学院 [24]
山东大学 [23]
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Insights into intercellular receptor-ligand binding kinetics in cell communication
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 953353
作者:
An, Chenyi
;
Wang, Xiaohuan
;
Song F(宋凡)
;
Hu, Jinglei
;
Li L(李龙)
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/10/23
cell communication
intercellular receptor-ligand binding kinetics
protein-membrane interaction
biomechanical force
bioelectric microenvironment
Influence of lipid rafts on pattern formation during T-cell adhesion
期刊论文
NEW JOURNAL OF PHYSICS, 2021, 卷号: 23, 期号: 4, 页码: 14
作者:
Li L(李龙)
;
Hu, Jinglei
;
Rozycki, Bartosz
;
Wang XH(王小环)
;
Wu, Helong
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  |  
浏览/下载:63/0
  |  
提交时间:2021/05/31
T-cell adhesion
immunological synapse
pattern formation
lipid raft
intercellular protein binding
MT-12 inhibits the growth and metastasis of bladder cancer cells via suppressing tumor angiogenesis in vivo and in vitro
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2019, 卷号: 8, 期号: 1
作者:
Xia, Chengxing
;
Luan, Ting
;
Chen, Yan
;
Yan, Ruping
;
Yuan, Shunhui
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  |  
浏览/下载:29/0
  |  
提交时间:2019/12/04
Cobra venom membrane toxin 12 (MT-12)
bladder cancer
matrix metalloproteinases (MMPs)
vascular endothelial growth factor (VEGF)
intercellular adhesion molecule-1 (ICAM-1)
Extracellular Vesicle-Mediated Communication Within Host-Parasite Interactions
期刊论文
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: Vol.9
作者:
Wu, Zhenyu
;
Wang, Lingling
;
Li, Jiaying
;
Wang, Lifu
;
Wu, Zhongdao
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
parasite
extracellular vesicle
intercellular communication
parasite-host interaction
exosome
Bone morphogenetic protein 6 affects cell-cell communication by altering the expression of Connexin43 in human granulosa-lutein cells
期刊论文
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2019, 卷号: 498
作者:
Wu, Hai-Cui
;
Chang, Hsun-Ming
;
Yi, Yuyin
;
Sun, Zhen-Gao
;
Lin, Yung-Ming
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  |  
浏览/下载:38/0
  |  
提交时间:2019/12/11
Bone morphogenetic protein 6
Connexin43
Gap junction intercellular
communication
Human granulosa-lutein cells
SMAD signaling
Ultrastructure of intestinal mucosa in diarrhea-predominant irritable bowel syndrome
期刊论文
PHYSIOLOGY INTERNATIONAL, 2019, 卷号: 106, 期号: 3, 页码: 225-235
作者:
Zhao, D-Y
;
Qi, Q-Q
;
Long, X.
;
Li, X.
;
Chen, F-X
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
diarrhea-predominant irritable bowel syndrome
intercellular junctional
complex
transmission electron microscopy
extracellular vesicles
intestinal barrier
Associations of intercellular adhesion molecule-1 rs5498 polymorphism with ischemic stroke: A meta-analysis
期刊论文
MOLECULAR GENETICS & GENOMIC MEDICINE, 2019, 卷号: 7, 期号: 6
作者:
Gao, Hua
;
Zhang, Xinhua
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/06
intercellular adhesion molecule-1 (ICAM-1)
ischemic stroke (IS)
meta-analysis
polymorphisms
食用蔬菜能吸收和积累微塑料
期刊论文
科学通报, 2019, 卷号: 64, 期号: 9, 页码: 928-934
作者:
李连祯
;
周倩
;
尹娜
;
涂晨
;
骆永明
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  |  
浏览/下载:63/0
  |  
提交时间:2020/06/17
微塑料
生菜
聚苯乙烯微球
吸收
积累
健康风险
microplastics
lettuce
polystyrene microbeads
uptake
accumulation
human health risk
Microplastic (MP, 100 nm-5 mm) may present an attributable risk to ecosystem and human health, and its pollution has become a global environmental concern. Despite a wealth of information on the accumulation of MPs in aquatic species, there is no information on the uptake and accumulation of MPs by higher plants. Terrestrial edible plants are directly exposed to MPs when agricultural soil was applied with organic manure, sewage sludge as fertilizer or plastic mulching. In this paper, the uptake of two sizes of polystyrene (PS) microbeads (0.2 and 1.0 mum) and then their distribution and migration in an edible plant lettuce were firstly investigated based on laboratory experiments. We used fluorescent markers to track PS microbeads in plant tissues and found fluorescence to be a sensitive and reliable detection method. Sections from untreated control lettuce showed no autofluorescence. When roots were treated with fluorescently labeled PS microbeads, the microbeads could be identified by its fluorescence. Our main study investigated the uptake of 0.2 mum beads, as few luminescence signals were observed in lettuce roots for 1.0 mum beads in our experiment. We observed that 0.2 mum fluorescent microbeads were extracellularly trapped in the root cap mucilage (which is a highly hydrated polysaccharide) and a dark green tip (which was typical of lettuce roots exposed to label PS beads) was usually visible to the naked eye. Confocal images revealed that the PS luminescence signals were mainly located in the vascular system and on the cell walls of the cortex tissue of the roots, indicated that the beads passed through the intercellular space via the apoplastic transport system. Once inside the central cylinder, the 0.2 mum PS beads were transferred from the roots to the stems and leaves via the vascular system following the transpiration stream. We also observed that the PS beads adhered to one another and self-assembled systematically into grape-like and (chain) string-like clusters in the intercellular space of the root and stem vascular tissue of lettuce plant. In contrast to the root and stem, PS beads were dispersed in the leaf tissue. Here, for the first time we provide evidence of the adherence, uptake, accumulation, and translocation of submicrometer MPs within an edible plant. Our findings highlight the previously underappreciated human exposure pathway to MPs through the consumption of contaminated crops and emphasize the need for new management strategies to control the release of MPs waste products into the terrestrial environment. Ultimately, the potential impacts of low range sized MPs on food safety of crop plants and human health need to be urgently considered.
Stimulation of chondrocytes and chondroinduced mesenchymal stem cells by osteoinduced mesenchymal stem cells under a fluid flow stimulus on an integrated microfluidic device
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 2, 页码: 2277-2288
作者:
Bao, Xuanwen
;
Li, Zhongyu
;
Liu, Hui
;
Feng, Ke
;
Yin, Fangchao
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  |  
浏览/下载:16/0
  |  
提交时间:2019/06/20
Microfluidics
Mesenchymal Stem Cells
Shear Stress
Intercellular Interactions
Metabolism
Benzo[a]pyrene-decreased gap junctional intercellular communication via calcium/calmodulin signaling increases apoptosis in TM4 cells
期刊论文
JOURNAL OF APPLIED TOXICOLOGY, 2018, 卷号: 38, 期号: 8
作者:
Ji, Xiaoli
;
Chou, Xin
;
Ge, Zehe
;
Ding, Fan
;
Gao, Hui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
apoptosis
benzo[a]pyrene
gap junctional intercellular communication
intracellular Ca2+ homeostasis
Sertoli cells
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