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Unique Proton Transportation Pathway in a Robust Inorganic Coordination Polymer Leading to Intrinsically High and Sustainable Anhydrous Proton Conductivity 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 页码: 6146-6155
作者:  Gui, Daxiang;  Dai, Xing;  Tao, Zetian;  Zheng, Tao;  Wang, Xiangxiang
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/30
Chains  Direct methanol fuel cells (DMFC)  Hydrogen bonds  Methanol fuels  Molecular dynamics  Nuclear magnetic resonance spectroscopy  Proton conductivity  Proton exchange membrane fuel cells (PEMFC)  Quantum chemistry  X ray crystallography  Zirconium compounds  Anhydrous proton conductivity  Coordination Polymers  High electrical power  Intermediate temperatures  Proton conducting materials  Proton-transport pathways  Quantum molecular dynamics  Solid-state NMR spectroscopy  Solid electrolytes  ammonia  electrolyte  inorganic coordination polymer  polymer  proton  unclassified drug  zirconium derivative  zirconium phosphate  Article  conductance  crystal structure  encapsulation  hydrogen bond  impedance  molecular dynamics  nuclear magnetic resonance spectroscopy  powder diffraction  proton transport  simulation  synthesis  temperature  X ray crystallography  
Delivery system for DNAzymes using arginine-modified hydroxyapatite nanoparticles for therapeutic application in a nasopharyngeal carcinoma model 期刊论文
International Journal of Nanomedicine, 2013, 卷号: 8, 期号: 1, 页码: 3107-3118
作者:  Chen, Yan;  Yang, Lifang*;  Huang, Suping;  Li, Zhi;  Zhang, Lu
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/03
DNAzymes are synthetic  single-stranded  catalytic nucleic acids that bind and cleave target mRNA in a sequence-specific manner  and have been explored for genotherapeutics. One bottleneck restricting their application is the lack of an efficient delivery system. As an inorganic nanomaterial with potentially wide application  nanohydroxyapatite particles (nHAP) have attracted increasing attention as new candidates for nonviral vectors. In this study  we developed an nHAP-based delivery system and explored its cellular uptake mechanisms  intracellular localization  and biological effects. Absorption of arginine-modified nanohydroxyapatite particles (Arg-nHAP) and DZ1 (latent membrane protein 1 [LMP1]-targeted) reached nearly 100% efficiency under in vitro conditions. Using specific inhibitors  cellular uptake of the Arg-nHAP/DZ1 complex was shown to be mediated by the energy-dependent endocytosis pathway. Further  effective intracellular delivery and nuclear localization of the complex was confirmed by confocal microscopy. Biologically  the complex successfully downregulated the expression of LMP1 in nasopharyngeal carcinoma cells. In a mouse tumor xenograft model  the complex was shown to be delivered efficiently to tumor tissue  downregulating expression of LMP1 and suppressing tumor growth. These results suggest that Arg-nHAP may be an efficient vector for nucleic acid-based drugs with potential clinical application.  
Enhanced superconductivity of SmFeAsO co-doped by Scandium and Fluorine to increase chemical inner pressure 期刊论文
JOURNAL OF SOLID STATE CHEMISTRY, 2012, 卷号: 194, 页码: 59-64
Chen, HJ; Zheng, M; Fang, AH; Yang, JH; Huang, FQ; Xie, XM(重点实验室); Jiang, MH(重点实验室)
收藏  |  浏览/下载:12/0  |  提交时间:2013/05/10
Investigation of HfO2 doping on GeTe for phase change memory 期刊论文
SOLID STATE SCIENCES, 2011, 卷号: 13, 期号: 11, 页码: 1943-1947
Lu, YG; Song, SN; song, zt(重点实验室); Ren, WC; Peng, C; Cheng, Y; Liu, B(重点实验室)
收藏  |  浏览/下载:9/0  |  提交时间:2013/05/10
Ab initio study of Sb2SexTe3-x(x=0, 1, 2) phase change materials 期刊论文
SOLID STATE SCIENCES, 2011, 卷号: 13, 期号: 1, 页码: 131-134
Li, XL; Sun, ZM; song, zt(重点实验室); Rao, F; Wu, LC; Liu, WL
收藏  |  浏览/下载:10/0  |  提交时间:2013/05/10
Monodisperse F-Substituted Hydroxyapatite Single-Crystal Nanotubes with Amphiphilic Surface Properties 期刊论文
2010, 2010
Hui, Junfeng; Xiang, Guolei; Xu, Xiangxing; Zhuang, Jing; Wang, Xun
收藏  |  浏览/下载:4/0
Effects of selenium on the structure and function of recombinant human S-adenosyl-L-methionine dependent arsenic (+3 oxidation state) methyltransferase in E-coli 期刊论文
2010, 2010
Geng, Zhirong; Song, Xiaoli; Xing, Zhi; Geng, Jinlong; Zhang, Sichun; Zhang, Xinrong; Wang, Zhilin
收藏  |  浏览/下载:13/0
Passivation of nanocrystalline TiO2 junctions by surface adsorbed phosphinate amphiphiles enhances the photovoltaic performance of dye sensitized solar cells 期刊论文
2010, 2010
Wang, Mingkui; Li, Xin; Lin, Hong; Pechy, Peter; Zakeeruddin, Shaik M.; Graetzel, Michael
收藏  |  浏览/下载:4/0  |  提交时间:2017/06/15
Influences of Co doping on the structural, optical and magnetic properties of ZnO nanorods synthesized by hydrothermal route 期刊论文
2010, 2010
Wang, Baiqi; Xia, Chunhui; Iqbal, Javed; Tang, Naijun; Sun, Zengrong; Lv, Yan; Wu, Lina
收藏  |  浏览/下载:7/0
Synthesis and Crystal Structure Analysis of 2-(3,5-Di-tert-butyl-2-hydroxyphenyl)-2-(3,4-dimethylphenyl) Acetic Acid Dimethylamine Salt 期刊论文
2010, 2010
Cheng Jie; Cheng Chang-Mei; He Juan; Shang Pei-Hua; Wang Ru-Ji; Zhao Yu-Fen
收藏  |  浏览/下载:5/0  |  提交时间:2017/06/15


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