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Mechanisms of microemulsion enhancing the oral bioavailability of puerarin: comparison between oil-in-water and water-in-oil microemulsions using the single-pass intestinal perfusion method and a chylomicron flow blocking approach 期刊论文
International Journal of Nanomedicine, 2013, 卷号: 8, 期号: 1, 页码: 4415-4426
作者:  Tang, Tian-Tian;  Hu, Xiong-Bin;  Liao, De-Hua;  Liu, Xin-Yi;  Xiang, Da-Xiong*
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
The purpose of the present work was to determine the mechanisms by which microemulsions (MEs) enhance the oral bioavailability of puerarin. The in situ perfusion method was used in rats to study the absorption mechanisms of an oil-in-water (O/W) microemulsion (O/W-ME) and a water-in-oil (W/O) microemulsion (W/O-ME). The possibility of lymphatic transport of the MEs was investigated using a chylomicron flow blocking approach. The results for the absorption mechanisms in the stomach and intestines indicated that the absorption characteristics of the O/W-ME and W/O-ME depend on the segment. The W/O-ME had higher internal membrane permeability than the O/W-ME. The results of the lymphatic transport analyses showed that both the O/W-ME and W/O-ME underwent lymphatic transport and that this pathway was a major contributor to the oral bioavailability of MEs. Furthermore  the type of ME can significantly affect the absorption of puerarin through the lymphatic system due to the oil content and the form of the microemulsion after oral administration. In conclusion  these data indicate that microemulsions are an effective and promising delivery system to enhance the oral bioavailability of poorly water-soluble drugs.  
Radiolytic syntheses of nanoparticles in supramolecular assemblies 期刊论文
胶体与界面科学进展, 2010
Chen, Qingde; Shen, Xinghai; Gao, Hongcheng
收藏  |  浏览/下载：2/0  |  提交时间：2015/11/10
Formation of super-concentrated hydrochloric acid in the third phase in tertiary amine N235-ptCl(6)(2-)-HCl system and its influences on the Pt microemulsion extraction 期刊论文
中国科学b辑 化学英文版, 2009
Huang Kun; Chen Jing; Zhang ChengFeng; Li ZhiHong; Pan QingHua; Sun Yan; Liu ShaoXuan; Liu XueXin; Li WeiHong; Yang ZhanLan; Weng ShiFu; Hu TianDou; Xu YiZhuang; Wu JinGuang
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/10
Microemulsions of N-Alkylimidazolium Ionic Liquid and Their Performance as Microreactors for the Photocycloaddition of 9-Substituted Anthracenes 期刊论文
Langmuir: The ACS Journal of Surfaces and Colloids, 2009, 卷号: 25, 期号: 10, 页码: 5484-5490
作者:  Li, XW;  Zhang, J;  Zheng, LQ;  Chen, B;  Wu, LZ
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/26
Reversed micelle formation in a model liquid-liquid extraction system 期刊论文
journal of colloid and interface science, 2008, 卷号: 322, 期号: 2, 页码: 605-610
Guo FQ; Li HF; Zhang ZF; Meng SL; Li DQ
收藏  |  浏览/下载：7/0  |  提交时间：2010/04/14
Role of solubilized water in the reverse ionic liquid microemulsion of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/benzene 期刊论文
The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical, 2007, 卷号: 111, 期号: 10, 页码: 2506-2513
作者:  Gao Y;  Li N;  Zheng LQ;  Bai XT;  Yu L
收藏  |  浏览/下载：2/0  |  提交时间：2020/01/03
Studies on the micropolarities of bmimBF(4)/TX-100/toluene ionic liquid microemulsions and their behaviors characterized by UV-visible spectroscopy 期刊论文
Langmuir: The ACS Journal of Surfaces and Colloids, 2007, 期号: 26, 页码: 1091-1097
作者:  Li N;  Gao YA;  Zheng LQ;  Zhang J;  Yu L
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/27
Rheological properties and microstructures of gelatin-containing microemulsion-based organogels 期刊论文
Colloids and Surfaces, A. Physicochemical and Engineering Aspects, 2006, 期号: 1, 页码: 67-73
作者:  Zhao XY;  Cao Q;  Zheng LQ;  Zhang GY
收藏  |  浏览/下载：0/0  |  提交时间：2020/01/03
Microemulsion copolymerization of styrene and acrylonitrile with n-butanol as the cosurfactant 期刊论文
Journal of Polymer Science, Part A. Polymer Chemistry, 2005, 卷号: 43, 期号: 1, 页码: 203-216
作者:  Shi YC;  Wu YS;  Hao JC;  Li GZ
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/03
Surprising arching sheet-like dendrites growing from BaF2 nanocubes 期刊论文
nanotechnology, 2004, 卷号: 15, 期号: 11, 页码: 1455-1458
Lian HZ; Ye ZR; Shi CS
收藏  |  浏览/下载：9/0  |  提交时间：2010/08/17

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