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北京大学 [24]
上海神经科学研究所 [7]
厦门大学 [5]
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期刊论文 [48]
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Human Pluripotent Stem Cells as Tools for Predicting Developmental Neural Toxicity of Chemicals: Strategies, Applications, and Challenges
期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 12, 页码: 755-768
作者:
Liang, Shengxian
;
Yin, Nuoya
;
Faiola, Francesco
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/10/21
developmental neural toxicity (DNT)
human pluripotent stem cells (hPSCs)
neural differentiation
neurons
astrocytes
oligodendrocytes
Delay and Recurrent Neural Networks: Computational Cybernetics of Systems Biology?
会议论文
2017 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS (SMC), 2017-01-01
作者:
Dimirovski, Georgi M.
;
Wang, Rui
;
Yang, Bin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
approximation computational models
artificial neurons
artificial recurrent neural networks
complex netwroks
cybernetics
human neural networks
living neurons
Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State
期刊论文
CELL STEM CELL, 2017
Li, Xiang
;
Liu, Defang
;
Ma, Yantao
;
Du, Xiaomin
;
Jing, Junzhan
;
Wang, Lipeng
;
Xie, Bingqing
;
Sun, Da
;
Sun, Shaoqiang
;
Jin, Xueqin
;
Zhang, Xu
;
Zhao, Ting
;
Guan, Jingyang
;
Yi, Zexuan
;
Lai, Weifeng
;
Zheng, Ping
;
Huang, Zhuo
;
Chang, Yanzhong
;
Chai, Zhen
;
Xu, Jun
;
Deng, Hongkui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2017/12/03
PLURIPOTENT STEM-CELLS
SMALL-MOLECULE COMPOUNDS
FUNCTIONAL-NEURONS
DIRECT CONVERSION
PURKINJE NEURONS
SOMATIC-CELLS
HUMAN ES
FUSION
HEPATOCYTES
DISEASE
Stress attenuates the flexible updating of aversive value
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Raio, Candace M.
;
Hartley, Catherine A.
;
Orederu, Temidayo A.
;
Li, Jian
;
Phelps, Elizabeth A.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
threat
stress
reversal learning
cognitive flexibility
computational modeling
ACUTE PSYCHOSOCIAL STRESS
COGNITIVE FLEXIBILITY
LOCUS-COERULEUS
HUMAN BRAIN
MEMORY
MODEL
FEAR
RESPONSES
NEURONS
ANXIETY
Predictive feature remapping before saccadic eye movements
期刊论文
JOURNAL OF VISION, 2017
He, Dongjun
;
Mo, Ce
;
Fang, Fang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/12/03
feature remapping
saccade
psychophysics
adaptation
visual aftereffect
LATERAL INTRAPARIETAL AREA
POSTERIOR PARIETAL CORTEX
HUMAN VISUAL-CORTEX
SELECTIVE ADAPTATION
CONTRAST ADAPTATION
RECEPTIVE-FIELDS
MACAQUE
REPRESENTATION
NEURONS
MOTION
Directed differentiation of basal forebrain cholinergic neurons from human pluripotent stem cells
期刊论文
JOURNAL OF NEUROSCIENCE METHODS, 2016, 卷号: 266
作者:
Hu Yao
;
Qu Zhuang-yin
;
Cao Shi-ying
;
Li Qi
;
Ma Lixiang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Basal forebrain cholinergic neurons
Human embryonic stem cells
Human induced pluripotent stem cells
Medial ganglionic eminence
Neural differentiation
Cell fate conversion-from the viewpoint of small molecules and lineage specifiers
期刊论文
DIABETES OBESITY & METABOLISM, 2016
Zhao, T.
;
Li, Y.
;
Deng, H.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/04
chemical reprogramming
lineage specifiers
pluripotency
"
small molecules
PLURIPOTENT STEM-CELLS
MOUSE SOMATIC-CELLS
DEFINED FACTORS
FUNCTIONAL-NEURONS
HUMAN FIBROBLASTS
PROGENITOR CELLS
REPROGRAMMING FACTORS
DRUG DISCOVERY
SELF-RENEWAL
IPS CELLS
seesaw model"
Propofol increases Bcl-2 Levels to protect cell from death
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016
Shu, Luowa
;
Chen, Zhiya
;
Pan, Chuxiong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
Propofol
microRNA
anesthetics
cell death
Bcl-2
INTRACELLULAR AMYLOID TOXICITY
HUMAN PRIMARY NEURONS
MICRORNA EXPRESSION
ANESTHESIA
SEVOFLURANE
APOPTOSIS
FAMILY
Propofol decreases p53 levels to prevent cell death
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016
Pan, Chuxiong
;
Shu, Luowa
;
Chen, Zhiya
;
Wang, Yu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
Propofol
microRNA
anesthetics
cell death
p53
INTRACELLULAR AMYLOID TOXICITY
HUMAN PRIMARY NEURONS
CEREBRAL-ISCHEMIA
MICRORNA EXPRESSION
ANESTHESIA
SEVOFLURANE
APOPTOSIS
RATS
REPERFUSION
PROTECTS
Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala
期刊论文
ELIFE, 2016
Atlas, Lauren Y.
;
Doll, Bradley B.
;
Li, Jian
;
Daw, Nataniel D.
;
Phelps, Elizabeth A.
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2017/12/03
FMRI,amygdala,fear conditioning,human,learning,neuroscience,orbitofrontal,reversal
UNILATERAL TEMPORAL LOBECTOMY
PREFRONTAL CORTEX
BRAIN MEDIATORS
NEURAL SYSTEMS
FEAR
REVERSAL
PAIN
EXTINCTION
NEURONS
REWARD
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