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Synthesis and biological evaluation of new HIV-1 protease inhibitors with purine bases as P2-ligands 期刊论文
2019, 卷号: 29, 期号: 12, 页码: 1541-1545
作者:  Zhu, Mei;  Dong, Biao;  Zhang, Guo-Ning;  Wang, Ju-Xian;  Cen, Shan
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands 期刊论文
2019, 卷号: 29, 期号: 3, 页码: 357-361
作者:  Zhu, Mei;  Du, Xiao-Nan;  Li, Yun-Ge;  Zhang, Guo-Ning;  Wang, Ju-Xian
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation 期刊论文
2017, 卷号: 137, 页码: 30-44
作者:  Bai Xiaoguang;  Yang Zhiheng;  Zhu Mei;  Dong Biao;  Zhou Lei
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/04
Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands 期刊论文
2015, 卷号: 25, 期号: 9, 页码: 1880-1883
作者:  Yang, Zhi-Heng;  Bai, Xiao-Guang;  Zhou, Lei;  Wang, Ju-Xian;  Liu, Hong-Tao
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/13
A comprehensive analysis of the influence of drug binding kinetics on drug action at molecular and systems levels 期刊论文
分子生物系统, 2013
Yin, Ning; Pei, Jianfeng; Lai, Luhua
收藏  |  浏览/下载:5/0  |  提交时间:2015/11/10
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:  Yan, Jianwei;  Huang, Ning;  Li, Shukun;  Yang, Liu-Meng;  Xing, Weiqiang
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:  Yan JW;  Huang N;  Li SK;  Yang LM;  Xing WQ
收藏  |  浏览/下载:16/0  |  提交时间:2012/03/19
Elucidating the Energetics of Entropically Driven Protein-Ligand Association: Calculations of Absolute Binding Free Energy and Entropy 期刊论文
journal of physical chemistry b, 2011
Deng, Nan-jie; Zhang, Peng; Cieplak, Piotr; Lai, Luhua
收藏  |  浏览/下载:4/0  |  提交时间:2015/11/12
An estimation method of binding free energy in terms of ABEEMsigmapi/MM and continuum electrostatics fused into LIE method 期刊论文
Journal of Computational Chemistry, 2010
作者:  Chen SL;  Zhao DX;  Yang ZZ.
收藏  |  浏览/下载:3/0  |  提交时间:2019/02/27
The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase 期刊论文
生物化学与生物物理学研究通讯, 2006
Wei, P; Fan, KQ; Chen, H; Ma, L; Huang, CK; Tan, L; Xi, D; Li, CM; Liu, Y; Cao, AN; Lai, LH
收藏  |  浏览/下载:3/0  |  提交时间:2015/11/11


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