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Predicting HIV-1 Protease Cleavage Sites With Positive-Unlabeled Learning 期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 3, 页码: 1-11
作者:  Li, ZF (Li, Zhenfeng)[ 1 ];  Hu, L (Hu, Lun)[ 2 ];  Tang, ZH (Tang, Zehai)[ 1 ];  Zhao, C (Zhao, Cheng)[ 1 ]
收藏  |  浏览/下载:36/0  |  提交时间:2021/05/06
Incorporating the Coevolving Information of Substrates in Predicting HIV-1 Protease Cleavage Sites 期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 6, 页码: 2017-2028
作者:  Hu, Lun;  Hu, Pengwei;  Luo, Xin;  Yuan, Xiaohui;  You, Zhu-Hong
收藏  |  浏览/下载:24/0  |  提交时间:2021/03/01
Accurate prediction of relative binding affinities of a series of HIV-1 protease inhibitors using semi-empirical quantum mechanical charge 期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2020, 页码: 8
作者:  Peng, Cheng;  Wang, Jinan;  Xu, Zhijian;  Cai, Tingting;  Zhu, Weiliang
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01
Synthesis and biological evaluation of new HIV-1 protease inhibitors with purine bases as P2-ligands 期刊论文
2019, 卷号: 29, 期号: 12, 页码: 1541-1545
作者:  Zhu, Mei;  Dong, Biao;  Zhang, Guo-Ning;  Wang, Ju-Xian;  Cen, Shan
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands 期刊论文
2019, 卷号: 29, 期号: 3, 页码: 357-361
作者:  Zhu, Mei;  Du, Xiao-Nan;  Li, Yun-Ge;  Zhang, Guo-Ning;  Wang, Ju-Xian
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:61/0  |  提交时间:2019/01/08
Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation 期刊论文
2017, 卷号: 137, 页码: 30-44
作者:  Bai Xiaoguang;  Yang Zhiheng;  Zhu Mei;  Dong Biao;  Zhou Lei
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/04
Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands 期刊论文
2015, 卷号: 25, 期号: 9, 页码: 1880-1883
作者:  Yang, Zhi-Heng;  Bai, Xiao-Guang;  Zhou, Lei;  Wang, Ju-Xian;  Liu, Hong-Tao
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/13
Identification and analysis of driver missense mutations using rotation forest with feature selection. 期刊论文
BioMed Research International, 2014, 卷号: Vol.2014, 页码: 905951
作者:  Du,Xiuquan;  Cheng,Jiaxing
收藏  |  浏览/下载:2/0  |  提交时间:2019/04/22
A comprehensive analysis of the influence of drug binding kinetics on drug action at molecular and systems levels 期刊论文
分子生物系统, 2013
Yin, Ning; Pei, Jianfeng; Lai, Luhua
收藏  |  浏览/下载:5/0  |  提交时间:2015/11/10


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