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Molecular Modeling Study of Checkpoint Kinase 1 Inhibitors by Multiple Docking Strategies and Prime/MM-GBSA Calculation
期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2011, 卷号: 32, 期号: 13
-
收藏
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浏览/下载:3/0
  |  
提交时间:2014/12/05
checkpoint kinase 1 inhibitors
induced-fit docking
QM/MM docking
binding-free energy
Prime/MM-GBSA
The application of template matching arithmetic on Strap-down North Seeking System (EI CONFERENCE)
会议论文
2011 International Conference on Mechatronic Science, Electric Engineering and Computer, MEC 2011, August 19, 2011 - August 22, 2011, Jilin, China
Li D.-N.
;
Zhu W.
;
Chen T.
收藏
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浏览/下载:13/0
  |  
提交时间:2013/03/25
In order to solve the problem of self-determination directional of theodolite
equipment based on dynamically tuned gyroscope is proposed. The principle of the Multi-position Strap-down North Seeking System is introduced. Mathematical model of the system is discussed. The factors that influence the precision are analyzed. In order to fit the curve of sampling data
back-propagation neural network arithmetic is used in data processing. As templates
curve model is saved at database of the VC software. The template matching arithmetic advanced the measure precision of this system. The measure time of the system is shortened within 1 minute
so it can save time for theodolite. 2011 IEEE.
Design of motion compensation mechanism of satellite remote sensing camera (EI CONFERENCE)
会议论文
International Symposium on Photoelectronic Detection and Imaging 2011: Space Exploration Technologies and Applications, May 24, 2011 - May 26, 2011, Beijing, China
Gu S.
;
Yan Y.
;
Xu K.
;
Jin G.
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浏览/下载:42/0
  |  
提交时间:2013/03/25
With the development of aerospace remote sensing technology
the ground resolution of remote sensing camera enhances continuously. Since there is relative motion between camera and ground target when taking pictures
the target image recorded in recording media is moved and blurred. In order to enhance the imaging quality and resolution of the camera
the image motion had to be compensated. In order to abate the effect of image motion to image quality of space camera and improve the resolution of the camera
the compensation method of image motion to space camera is researched. First
the reason of producing drift angle and adjustment principle are analyzed in this paper. This paper introduce the composition and transmission principle of image motion compensation mechanism. Second
the system adopts 80C31 as controller of drift angle
and adopts stepping motor for actuators
and adopts absolute photoelectric encoder as the drift Angle measuring element. Then the control mathematical model of the image motion compensation mechanism are deduced
and it achieve the closed-loop control of the drift angle position. At the last
this paper analyses the transmission precision of the mechanism. Through the experiment
we measured the actual precision of the image motion compensation mechanism
and compared with the theoretical analysis. There are two major contributions in this paper. First
the traditional image motion compensation mechanism is big volume and quality heavy. This has not fit for the development trend of space camera miniaturization and lightweight. But if reduce the volume and quality of mechanism
it will bring adverse effects for the precision and stiffness of mechanism. For this problem
This paper designed a image motion compensation that have some advantages such as small size
light weight at the same time
high precision
stiffness and so on. This image motion compensation can be applicable to the small optics cameras with high resolution. Second
the traditional mechanism control need to corrected
fitting and iterative for the control formula of mechanism. Only in this way
we can get the optimal control mathematical model. This paper has high precision of the control formula derived. It can achieve the high precision control without fitting
It also simplify the difficulty of control mathematical model establishment. This paper designed the range of adjusting of image motion compensation mechanism between -5 +5. Based on choosing-5
-4
-3
-2
-1
0
+1
+2
+3
+4
+4 as the expectation value of the imaginary drift angle
we get ten groups of the fact data in adjusting drift angle measured. The test results show that the precision of the drift angle control system can be achieved in 1. It can meet the system requirements that the precision of the control system is less than 3'
and it can achieve the high-precision image motion compensation. 2011 SPIE.
Data processing method of multi-position strap-down north seeking system based on SVD (EI CONFERENCE)
会议论文
2011 International Conference on Mechatronic Science, Electric Engineering and Computer, MEC 2011, August 19, 2011 - August 22, 2011, Jilin, China
Shen C.-W.
;
Liu C.
;
Yu S.-B.
;
Wang Z.-Q.
;
Li J.-R.
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浏览/下载:25/0
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提交时间:2013/03/25
With the aim to fit the sin wave curve of a multi-position strap-down north seeking system and to calculate the real north angle accurately
the principles of the system and the algorithm of singular value decomposition(SVD) are introduced. The factors influencing the measuring precision are also analyzed. Then
the algorithm is adopted to fit curves. Experimental results indicate that the singular value decomposition is very precise
for its error sum is 1.1102V
and the squared error is 2.8mV. Moreover
for phase angle measurement
measured six times in same direction
the squared error is 24 (1). The method based on SVD can satisfy the system precision requirements of curve-fitting north seeking systems. 2011 IEEE.
Color videos' multichannel combination for bandwidth reduction and fast frequency domain processing (EI CONFERENCE)
会议论文
2nd International Workshop on Education Technology and Computer Science, ETCS 2010, March 6, 2010 - March 7, 2010, Wuhan, Hubei, China
Li S.
;
Jing S.
;
Song Y.
;
Zhang B.
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浏览/下载:13/0
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提交时间:2013/03/25
The real color video consumes much transfer bandwidth and the resource of the hardware. A new approach is introduced to process the real color video images in real-time using color components combination to fit to the limited transmission bandwidth. The Y
U
V planes of video images are packed to construct a 2 dimensional complex array. Through the decomposition of frequency domain
the Y
U
V frequency can be got respectively by performing Fourier transform a time on the specific complex array. These frequencies can be filtered to generate the final filtered images. The experiment results show that the proposed algorithm is 3X speed compared to the traditional algorithm
and it reduces 1/3 bandwidth of video data stream. 2010 IEEE.
不同病程脑动静脉畸形血管中血管内皮生长因子及其受体的基因表达分析
期刊论文
中国临床神经科学, 2009, 卷号: 17, 期号: 6
作者:
徐宏治(1,2)
;
陈衔城(1,2)
;
秦智勇(1,2)
;
顾宇翔(1,2)
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
动静脉畸形血管
血管内皮生长因子
Fit-1
mRNA
Flk-1/KDR
Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
期刊论文
PROTEIN SCIENCE, 2008, 卷号: 17, 期号: 9, 页码: 1542-1554
作者:
Peng, YJ
;
Zhong, C
;
Huang, W
;
Ding, JP
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2015/07/22
catalytic mechanism
conformational change
IDH
Idp1p
induced-fit
isocitrate dehydrogenase
NADP
Relative radiometric correction on panchromatic images of the Beijing-1 micro-satellite - art. no. 67900W
会议论文
Remote Sensing and Gis Data Processing and Applications; and Innovative Multispectral Technology and Applications, Pts 1 and 2, Bellingham
Liu, Xiang
;
Chen, ZhengChao
;
Zhang, Hao
;
Luo, WenFei
;
Zhang, Xia
收藏
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浏览/下载:21/0
  |  
提交时间:2014/12/07
Beijing-1
micro-satellite
relative radiometric correction
array
response
de-striping
FIR filter
curve fit
Conformational dynamics of RNA-peptide binding: A molecular dynamics simulation study
期刊论文
Biophysical Journal, 2006, 卷号: 90, 期号: 2, 页码: 391-399
作者:
Mu YG
;
Stock G
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
HIV-1 TAR RNA
RESIDUAL DIPOLAR COUPLINGS
NUCLEIC-ACID STRUCTURE
INDUCED FIT
PROTEIN RECOGNITION
FREE-ENERGIES
MOTIONS
COMPLEX
MODEL
ARGININAMIDE
Measuring the system gain of the TDI CCD remote sensing camera (EI CONFERENCE)
会议论文
Advanced Materials and Devices for Sensing and Imaging II, November 8, 2004 - November 10, 2004, Beijing, China
Ya-xia L.
;
Hai-ming B.
;
Jie L.
;
Jin R.
;
Zhi-hang H.
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2013/03/25
The gain of a TDI CCD camera is the conversion between the number of electrons recorded by the TDI CCD and the number of digital units (counts) contained in the CCD image"[1]. TDI CCD camera has been a main technical approach for meeting the requirements of high-resolution and lightweight of remote sensing equipment. It is useful to know this conversion for evaluating the performance of the TDI CCD camera. In general
a lower gain is better. However
the resulting slope is the gain of the TDI CCD. We did the experiments using the Integration Sphere in order to get a flat field effects. We calculated the gain of the four IT-EI-2048 TDI CCD. The results and figures of the four TDI CCD are given.
this is only true as long as the total well depth (number of electrons that a pixel can hold) of the pixels can be represented. High gains result in higher digitization noise. System gains are designed to be a compromise between the extremes of high digitization noise and loss of well depth. In this paper
the mathematical theory is given behind the gain calculation on a TDI CCD camera and shows how the mathematics suggests ways to measure the gain accurately according to the Axiom Tech. The gains were computed using the mean-variance method
also known as the method of photon transfer curves. This method uses the effect of quantization on the variance in the measured counts over a uniformly illuminated patch of the detector. This derivation uses the concepts of signal and noise. A linear fit is done of variance vs. mean
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