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西安交通大学 [16]
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山东大学 [12]
南华大学 [10]
复旦大学上海医学院 [9]
上海药物研究所 [8]
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期刊论文 [102]
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Effects of FOSL1 silencing on osteosarcoma cell proliferation, invasion and migration through the ERK/AP-1 signaling pathway
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 4
作者:
Sun, Yifu
;
Liu, Jianguo
;
Han, Yu
;
Zhao, Xingyu
;
Sui, Yutong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
apoptosis
extracellular-signal-regulated kinase (ERK)
activator protein-1 (AP-1) signaling pathway
Fos-like antigen-1 (FOSL1)
gene silencing
invasion
migration
osteosarcoma (OS)
proliferation
a11anoveldiarylacylhydrazonederivativeexertsneuroprotectionagainstischemicinjuryinvitroandinvivo
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 2, 页码: 160
作者:
Feng Hongxuan
;
Li Chunpu
;
Shu Shuangjie
;
Liu Hong
;
Zhang Haiyan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
FOCAL CEREBRAL-ISCHEMIA
OXIDATIVE STRESS
DRUG DISCOVERY
COLORIMETRIC ASSAY
TREAT STROKE
MECHANISMS
DISEASE
OXYGEN
PROTECTS
MODELS
ischemic stroke
neuroprotection
diaryl acylhydrazone
oxygen glucose deprivation
middle cerebral artery occlusion
protein kinase B
extracellular signal-regulated kinase
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:
Liu, Feifei
;
Yang, Xiaotong
;
Geng, Meiyu
;
Huang, Min
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Mitogen-activated protein kinases
Extracellular signal-regulated kinase
ERK inhibitor
ERK kinase
Cancer therapy
Drug resistance
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response
期刊论文
CELL BIOLOGY INTERNATIONAL, 2018, 卷号: 42, 期号: 11
作者:
Yu, Bo
;
Zhao, Yanan
;
Zhang, Hongli
;
Xie, Di
;
Nie, Wei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
extracellular signal-regulated protein kinase 5
inflammation
miR-143-3p
myocardial hypertrophy
proliferator-activated receptor
Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants
期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:
Mao, Xiao-Yuan*
;
Jin, Ming-Zhu
;
Chen, Jin-Fei*
;
Zhou, Hong-Hao
;
Jin, Wei-Lin*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
PD
Parkinson's disease
AD
Alzheimer's disease
EGCG
(−)-Epigallocatechin-3-gallate
NRF2
NF-E2-related factor 2
ROS
reactive oxygen species
H2O2
hydrogen peroxide
ER
endoplasmic reticulum
GPX
glutathione-peroxidase
NOX
NADPH oxidases (NOXs)
LOX
lipoxygenases
ERK
extracellular signal-regulated kinase
JNK
c-Jun amino-terminal kinase
MAPK
mitogen-activated protein kinase
HNE
4-hydroxy-2-nonenol
ARE
antioxidant responsive element
GST
glutathione S-transferase
IFNγ
interferon-γ
LPS
lipopolysaccharide
SOD
superoxide dismutase
TNF-α
tumor necrosis factor-α
APP
β-amyloid precursor protein
SAM
S-adenosylmethionine
MAT
methionine adenosyltransferase
SAH
Sadenosyl homocysteine
MT
methyltransferases
BDNF
brain-derived neurotrophic factor
Nutraceuticals
Neuroprotection
Anti-cancer
ROS addiction
Ferroptosis
Oxidative stress
Sorafenib inhibited cell growth through the MEK/ERK signaling pathway in acute promyelocytic leukemia cells
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 页码: 5620-5626
作者:
Zhang, Yunjie
;
Li, Gangcan
;
Liu, Xin
;
Song, Yanping
;
Xie, Jia
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/11/26
sorafenib
cell proliferation
mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway
acute promyelocytic leukemia
apoptosis
Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 页码: 13989-14000
作者:
Qian, Kevin
;
Wang, Simeng
;
Fu, Minnie
;
Zhou, Jinfeng
;
Singh, Jay Prakash
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/11/26
extracellular-signal-regulated kinase (ERK)
CCAAT-enhancer-binding protein (C
E1A binding protein p300 (P300)
EBP)
O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT)
O-linked N-acetylglucosamine (O-GlcNAc)
pancreatic cancer
O-GlcNAcase (OGA)
O-GlcNAcylation
High glucose upregulates endothelin type B receptors in vascular smooth muscle cells via the downregulation of Sirt1
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 页码: 439-445
作者:
Lin, Yan
;
Zhao, Yan
;
Liu, Enqi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
endothelin type B receptor
resveratrol
extracellular signal-regulated protein kinase 1
2
high glucose
silent information regulator family protein 1
IGF1/MAPK/ERK signaling pathway-mediated programming alterations of adrenal cortex cell proliferation by prenatal caffeine exposure in male offspring rats
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 341
作者:
Chen, Guanghui
;
Yuan, Chao
;
Duan, Fangfang
;
Liu, Yanyan
;
Zhang, Jinzhi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Prenatal caffeine exposure
Glucocorticoid
Adrenal cell proliferation
Insulin-like growth factor 1
Mitogen-activated protein kinase/extracellular signal-regulated kinase
Targeting cysteine-rich angiogenic inducer-61 by antibody immunotherapy suppresses growth and migration of non-small cell lung cancer
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 2, 页码: 730-738
作者:
Li, Xinpeng
;
Yuan, Naxin
;
Lin, Lingdan
;
Yin, Lixia
;
Qu, Yiqing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
cysteine-rich angiogenic inducer-61
anti-cysteine-rich angiogenic
inducer-61
apoptosis
migration
extracellular signal-regulated
kinases
protein kinase B
non-small cell lung cancer
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