×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
山东大学 [11]
北京大学 [9]
四川大学 [9]
上海药物研究所 [6]
中国医学科学院 北京... [6]
长春应用化学研究所 [5]
更多...
内容类型
期刊论文 [91]
其他 [1]
学位论文 [1]
发表日期
2021 [2]
2019 [6]
2018 [9]
2017 [9]
2016 [7]
2015 [6]
更多...
学科主题
Chemistry [2]
Chemistry ... [1]
Chemistry,... [1]
Chemistry,... [1]
Materials ... [1]
Oncology [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共93条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Relationship between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and COVID-19 incidence or severe disease
期刊论文
JOURNAL OF HYPERTENSION, 2021, 卷号: 39, 期号: 8, 页码: 1717-1724
作者:
Tse, Gary
;
Zhou, Jiandong
;
Lee, Sharen
;
Wong, Wing Tak
;
Li, Xintao
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/08/15
angiotensin receptor blockers
angiotensin-converting enzyme inhibitors
COVID-19 incidence
Glycosyl triazoles as novel insect beta-N-acetylhexosaminidase OfHex1 inhibitors: Design, synthesis, molecular docking and MD simulations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 页码: 2315-2322
作者:
Dong, Lili
;
Shen, Shengqiang
;
Chen, Wei
;
Lu, Huizhe
;
Xu, Dongdong
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/12/02
beta-N-acetyl-D-hexosaminidase
OfHex1
Glycosyl triazoles
Enzyme inhibitors
Molecular docking
MD simulations
Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 517, 期号: 1
作者:
Chang, Jian
;
Tang, Nan
;
Fang, Qi
;
Zhu, Kongfan
;
Liu, Lei
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2019/12/05
Colorectal cancer
COX and LOX metabolic pathways
Enzyme inhibitors
Apoptosis
Proliferation
PTEN/PI3K/AKT pathway
Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:
Yevglevskis, Maksims
;
Nathubhai, Amit
;
Wadda, Katty
;
Lee, Guat L.
;
Al-Rawi, Suzanne
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/11
alpha-Methylacyl-CoA racemase (AMACR, P504S)
Branched-chain fatty acid
metabolism
Castrate-resistant prostate cancer (CRPC)
Drug
lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive
inhibition
Rational drug design
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
Bioorganic Chemistry, 2019, 卷号: 92
作者:
Yevglevskis M.
;
Nathubhai A.
;
Wadda K.
;
Lee G.L.
;
Al-Rawi S.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/11
Branched-chain fatty acid metabolism
Castrate-resistant prostate cancer (CRPC)
Drug lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive inhibition
Rational drug design
Structure-activity relationships
α-Methylacyl-CoA racemase (AMACR, P504S)
Nucleoside and N-acetyldopamine derivatives from the insect Aspongopus chinensis.
期刊论文
Fitoterapia, 2019, 卷号: Vol.132, 页码: 82-87
作者:
Yan, Yong-Ming
;
Luo, Qin
;
Di, Lei
;
Shi, Yan-Ni
;
Tu, Zheng-Chao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
ALTERNATIVE
medicine
*BIOLOGICAL
products
*CATECHOLAMINES
*CELL
lines
*ENZYME
inhibitors
*HIGH
performance
liquid
chromatography
*INSECTS
*MOLECULAR
structure
*NONSTEROIDAL
anti-inflammatory
agents
*NUCLEOSIDES
*PROTEIN
kinases
*RESEARCH
funding
*SPECTRUM
analysis
*CYCLOOXYGENASE
2
*IN
vitro
studies
*JANUS
kinases
*PHARMACODYNAMICS
Ligand fishing of anti-neurodegenerative components from Lonicera japonica using magnetic nanoparticles immobilised with monoamine oxidase B
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2019, 卷号: 42, 期号: 6, 页码: 1289-1298
作者:
Wu, Gui-Fang
;
Jiang, Xiao-Lan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/10/27
enzyme inhibitors
Lonicera japonica
magnetic nanoparticles
monoamine oxidase B
neurodegenerative diseases
A manganese-salen complex as dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 120
作者:
Zhu, Ming-rong
;
Zhou, Jie
;
Jin, Yi
;
Gao, Li-Hui
;
Li, Ling
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/04
Manganese(II)
Schiff base complex
Enzyme inhibitors
Dipeptidyl peptidase IV
Molecular docking
Enzyme Inhibitor Antibiotics and Antibiotic-Associated Diarrhea in Critically Ill Patients
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 8781-8788
作者:
Zhang, Yanshu
;
Sun, Jingjing
;
Zhang, Ling
;
Liu, Yu
;
Guo, Litao
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/11/19
Enzyme Inhibitors
Diarrhea
Antifungal Agents
Intensive Care Units
Clostridium Difficile
©版权所有 ©2017 CSpace - Powered by
CSpace