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期刊论文 [37]
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Biosynthesis of acetylacetone inspired by its biodegradation
期刊论文
BIOTECHNOLOGY FOR BIOFUELS, 2020, 卷号: 13, 期号: 1, 页码: 10
作者:
Zhou, Yifei
;
Ding, Yamei
;
Gao, Wenjie
;
Wang, Jichao
;
Liu, Xiutao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/24
Acetylacetone biosynthesis
Acetylacetone-cleaving enzyme
Rational design
Site-directed mutagenesis
beta-Dicarbonyl compounds
Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 29
作者:
Ning, Jing
;
Wang, Wei
;
Ge, Guangbo
;
Chu, Peng
;
Long, Feida
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
analytical methods
cytochrome P450 3A4
enzyme
activatable probes
fluorescent probes
olecular design
Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 页码: 9959-9963
作者:
Ning, Jing
;
Wang, Wei
;
Ge, Guangbo
;
Chu, Peng
;
Long, Feida
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/12/02
analytical methods
cytochrome P450 3A4
enzyme
activatable probes
fluorescent probes
olecular design
Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:
Yevglevskis, Maksims
;
Nathubhai, Amit
;
Wadda, Katty
;
Lee, Guat L.
;
Al-Rawi, Suzanne
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/11
alpha-Methylacyl-CoA racemase (AMACR, P504S)
Branched-chain fatty acid
metabolism
Castrate-resistant prostate cancer (CRPC)
Drug
lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive
inhibition
Rational drug design
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
Bioorganic Chemistry, 2019, 卷号: 92
作者:
Yevglevskis M.
;
Nathubhai A.
;
Wadda K.
;
Lee G.L.
;
Al-Rawi S.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/11
Branched-chain fatty acid metabolism
Castrate-resistant prostate cancer (CRPC)
Drug lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive inhibition
Rational drug design
Structure-activity relationships
α-Methylacyl-CoA racemase (AMACR, P504S)
The Third Generation of Artificial Dye-Decolorizing Peroxidase Rationally Designed in Myoglobin
期刊论文
ACS CATALYSIS, 2019, 卷号: 9, 期号: 9, 页码: 7888-7893
作者:
Zhang, Ping[1]
;
Xu, Jiakun[2]
;
Wang, Xiao-Juan[3]
;
He, Bo[4]
;
Gao, Shu-Qin[5]
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/01/02
dye-decolorizing peroxidases
artificial enzyme
protein design
myoglobin
substrate-binding
molecular docking
Target Enzyme‐Activated Two‐Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two‐Dimensional Design Strategy
期刊论文
Angewandte Chemie (International ed. in English), 2019, 卷号: 58, 期号: 29, 页码: 9959-9963
作者:
Jing Ning
;
Wei Wang
;
Guangbo Ge
;
Peng Chu
;
Feida Long
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
analytical methods
cytochrome P450 3A4
enzyme-activatable probes
fluorescent probes
molecular design
The Third Generation of Artificial Dye-Decolorizing Peroxidase Rationally Designed in Myoglobin
期刊论文
ACS CATALYSIS, 2019, 卷号: 9, 期号: 9, 页码: 7888-7893
作者:
Zhang, Ping
;
Xu, Jiakun
;
Wang, Xiao-Juan
;
He, Bo
;
Gao, Shu-Qin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
dye-decolorizing peroxidases
artificial enzyme
protein design
myoglobin
substrate-binding
molecular docking
Tuning SpyTag-SpyCatcher mutant pairs toward orthogonal reactivity encryption
期刊论文
CHEMICAL SCIENCE, 2017
Liu, Yajie
;
Liu, Dong
;
Yang, Wei
;
Wu, Xia-Ling
;
Lai, Luhua
;
Zhang, Wen-Bin
收藏
  |  
浏览/下载:114/0
  |  
提交时间:2017/12/03
PROTEINS IN-VIVO
DIRECTED EVOLUTION
GIANT MOLECULES
CHEMISTRY
DESIGN
TOPOLOGY
ENZYME
BOND
Computational design of ligand-binding proteins
期刊论文
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2017
Yang, Wei
;
Lai, Luhua
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2017/12/03
ENZYME DESIGN
TRANSCRIPTION FACTORS
MOLECULAR-DYNAMICS
HIGH-AFFINITY
DOCKING
SPECIFICITY
SELECTIVITY
TARGETS
SITES
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