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期刊论文 [80]
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Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S)
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:
Li, Qiannan
;
Zhang, Tao
;
Li, Shiliang
;
Tong, Linjiang
;
Li, Junyu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
EGFR
mutant
inhibitor
C797S
The Unique Spatial-Temporal Treatment Failure Patterns of Adjuvant Gefitinib Therapy: A Post Hoc Analysis of the ADJUVANT Trial (CTONG 1104)
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2019, 卷号: 14, 期号: 3
作者:
Xu, Song-Tao
;
Xi, Jun-Jie
;
Zhong, Wen-Zhao
;
Mao, Wei-Min
;
Wu, Lin
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/05
NSCLC
EGFR
tyrosine kinase inhibitor
gefitinib
adjuvant chemotherapy
Epidermal Growth Factor Receptor Mutation Detection in Cerebrospinal Fluid of Lung Adenocarcinoma Patients with Leptomeningeal Metastasis
期刊论文
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2019, 卷号: 34, 期号: 2
作者:
Huang, Ruofan
;
Ge, Mengxi
;
Zhou, Xinli
;
Ji, Xiaoyu
;
Liao, Li
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
cerebrospinal fluid
EGFR
leptomeningeal metastasis
nonsmall cell lung cancer
tyrosine kinase inhibitor
Frequency, clinical features and differential response to therapy of concurrent ALK/EGFR alterations in Chinese lung cancer patients
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13
作者:
Zhang, Tengfei
;
Zhang, Lu
;
Xie, Yuancai
;
Li, Bing
;
Ma, Yafeng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
EGFR alteration
ALK rearrangement
nonsmall cell lung cancer
EML4-ALK
tyrosine kinase inhibitor
Frequency, clinical features and differential response to therapy of concurrent ALK/EGFR alterations in Chinese lung cancer patients
期刊论文
Drug Design, Development and Therapy, 2019, 卷号: 13, 页码: 1809-1817
作者:
Liu, Jixian
;
Mu, Zhimin
;
Liu, Li
;
Li, Kang
;
Jiang, Richeng
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/03
ALK rearrangement
EGFR alteration
EML4-ALK
Nonsmall cell lung cancer
Tyrosine kinase inhibitor
A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation
期刊论文
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: Vol.38 No.1
作者:
Meifang Li
;
Jilong Yang
;
Lenghe Zhang
;
Sanfang Tu
;
Xuan Zhou
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Epidermal growth factor receptor (EGFR)
Epidermal growth factor receptor pathway substrate 8 (Eps8)
Breast cancer
NSCLC, small-molecule inhibitor
A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation.
期刊论文
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: Vol.38 No.1
作者:
Li, Meifang
;
Yang, Jilong
;
Zhang, Lenghe
;
Tu, Sanfang
;
Zhou, Xuan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/13
Breast cancer
Epidermal growth factor receptor (EGFR)
Epidermal growth factor receptor pathway substrate 8 (Eps8)
NSCLC, small-molecule inhibitor
Therapeutic Effect Of First-Line EGFR-TKIs Combined With Concurrent Cranial Radiotherapy On NSCLC Patients With EGFR Activating Mutation And Brain Metastasis: A Retrospective Study
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12, 页码: 8311-8318
作者:
An, Ning
;
Wang, Haoyi
;
Li, Ji
;
Zhai, Xiaoyang
;
Jing, Wang
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/12/11
non-small cell lung cancer
EGFR mutation
brain metastasis
radiotherapy
tyrosine kinase inhibitor
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