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北京大学 [21]
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上海药物研究所 [8]
复旦大学上海医学院 [8]
山东大学 [7]
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期刊论文 [111]
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BARN: Behavior-Aware Relation Network for multi-label behavior detection in socially housed macaques
期刊论文
ZOOLOGICAL RESEARCH, 2023, 卷号: 44, 期号: 6, 页码: 1026-1038
作者:
Yang, Sen
;
Chen, Zhi-Yuan
;
Liang, Ke-Wei
;
Qin, Cai-Jie
;
Yang, Yang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/22
Macaque behavior
Drug safety
assessment
Multi-label behavior detection
Behavioral
similarity
Relation network
Risk of drug-drug interactions in China's fight against COVID-19 and beyond
期刊论文
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 196, 页码: 2
作者:
Zhang, Qingpeng
;
Yang, Jiannan
;
Zeng, Daniel Dajun
;
Feng, Yibin
;
Wong, Ian C. K.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/26
Drug interactions
Protein-protein interactions
Network science
COVID-19
HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds
期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:
Qian, Ying
;
Li, Xuelian
;
Wu, Jian
;
Zhou, Aimin
;
Xu, Zhijian
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  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
compound-protein interaction
convolutional neural network (CNN)
drug-drug interaction
image processing
structural images
Application of network link prediction in drug discovery
期刊论文
BMC Bioinformatics, 2021, 卷号: 22, 期号: 1
作者:
Abbas,Khushnood
;
Abbasi,Alireza
;
Dong,Shi
;
Niu,Ling
;
Yu,Laihang
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  |  
浏览/下载:27/0
  |  
提交时间:2021/05/17
Data-driven drug discovery
Network link prediction
Poly-pharmacy
Poly-pharmacy side effects prediction
Drug-target prediction
Disrupted hemispheric connectivity specialization in patients with major depressive disorder: Evidence from the REST-meta-MDD Project
期刊论文
JOURNAL OF AFFECTIVE DISORDERS, 2021, 卷号: 284, 页码: 217-228
作者:
Ding, Yu-Dan
;
Yang, Ru
;
Yan, Chao-Gan
;
Chen, Xiao
;
Bai, Tong-Jian
收藏
  |  
浏览/下载:177/0
  |  
提交时间:2021/04/19
Major depressive disorder
hemispheric asymmetry
parameter of asymmetry
fMRI Abbreviations ACC, Anterior cingulate gyrus
DLPFC, Dorsolateral prefrontal cortex
DMN, Default mode network
DPARSF, Data Processing Assistant for Resting-State fMRI
DSM, Diagnosic and Statistical Manual of Mental Disorders
EEG, Electroencephalographic
FC, Functional connectivity
FDR, False discovery rate
FEDN, First-episode, drug-naive
FEF, Frontal eye fields
fMRI, Functional magnetic resonance imaging
HAMD, Hamilton Depression Rating Scale
HC, Healthy control
IFG, Inferior frontal gyrus
IPL, Inferior parietal lobule
IPS/SPL, Intraparietal sulcus/superior parietal lobule
LMM, Linear mixed model
MDD, Major depressive disorder
MFG, Middle frontal gyrus
MTG, Middle temporal gyrus
PAS, Parameter of asymmetry
PCC, Posterior cingulate cortex
PET, Positron emission tomography
ROIs, Regions of interest
rs-fMRI, Resting-state fMRI
rTMS, repetitive transcranial magnetic stimulation
STS, Superior temporal sulcus
VMHC, Voxel-mirrored homotopic connectivity
Editorial: Computational Learning Models and Methods Driven by Omics for Precision Medicine
期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 4
作者:
Zhu, Lei
;
Cai, Hongmin
;
Zhang, Fa
;
Zou, Quan
;
Wei, Yanjie
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/01
omics
machine learning
drug
RNA
disease
biomarker
network analysis
deep learning
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
Tan, Xiaoqin
;
Jiang, Xiangrui
;
He, Yang
;
Zhong, Feisheng
;
Li, Xutong
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design
Prediction of Drug-Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 期号: 6, 页码: 1-9
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Luo, GX (Luo, Gong-Xu)[ 1,2 ]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/09/09
drug-target interactions
molecular association network
attribute feature
behavior feature
random forest
Prediction of drug-target interactions from multi-molecular network based on LINE network representation method
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 卷号: 18, 期号: 1, 页码: 1-11
作者:
Ji, BY (Ji, Bo-Ya)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Jiang, HJ (Jiang, Han-Jing)[ 1,2 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
Zheng, K (Zheng, Kai)[ 3 ]
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/10/23
Drug-target interactions
Heterogeneous information network
LINE
Random forest
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