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浏览/检索结果: 共4条，第1-4条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents 期刊论文 BIOORGANIC CHEMISTRY, 2019, 卷号: 92 作者:  Yevglevskis, Maksims;  Nathubhai, Amit;  Wadda, Katty;  Lee, Guat L.;  Al-Rawi, Suzanne 收藏  |  浏览/下载：34/0  |  提交时间：2019/12/11 alpha-Methylacyl-CoA racemase (AMACR, P504S)  Branched-chain fatty acid  metabolism  Castrate-resistant prostate cancer (CRPC)  Drug  lipophilicity  Enzyme inhibitors  Ibuprofen  Mixed competitive  inhibition  Rational drug design  Structure-activity relationships   Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents 期刊论文 Bioorganic Chemistry, 2019, 卷号: 92 作者:  Yevglevskis M.;  Nathubhai A.;  Wadda K.;  Lee G.L.;  Al-Rawi S. 收藏  |  浏览/下载：40/0  |  提交时间：2019/12/11 Branched-chain fatty acid metabolism  Castrate-resistant prostate cancer (CRPC)  Drug lipophilicity  Enzyme inhibitors  Ibuprofen  Mixed competitive inhibition  Rational drug design  Structure-activity relationships  α-Methylacyl-CoA racemase (AMACR, P504S)   Optimization of the Antiviral Potency and Lipophilicity of Halogenated 2,6-Diarylpyridinamines as a Novel Class of HIV-1 NNRTIS 期刊论文 CHEMMEDCHEM, 2014, 卷号: 9, 期号: 7 作者:  Wu, Zhi-Yuan;  Liu, Na;  Qin, Bingjie;  Huang, Li;  Yu, Fei 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/19 anti-HIV activity  antiviral agents  diarylpyridinamines  drug-like properties  lipophilicity   Computation of octanol-water partition coefficients by guiding an additive model with knowledge 期刊论文 journal of chemical information and modeling, 2007 Cheng, Tiejun; Zhao, Yuan; Li, Xun; Lin, Fu; Xu, Yong; Zhang, Xinglong; Li, Yan; Wang, Renxiao; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/12 ATOMIC PHYSICOCHEMICAL PARAMETERS  DIRECTED QUANTITATIVE STRUCTURE  SMALL ORGANIC-MOLECULES  DRUG DISCOVERY  LOG-P  PREDICTION  LIPOPHILICITY  SOLUBILITY  ADMET  QSAR