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四川大学 [25]
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期刊论文 [74]
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2018 [9]
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Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 3
作者:
He, Xiang-hu
;
Jordan, Chloe J.
;
Vemuri, Kiran
;
Bi, Guo-hua
;
Zhan, Jia
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
CB1 receptors
AM4113
SR141716A
CB1 neutral antagonist
CB1 inverse agonist
drug reward
aversion
depression
self-administration
brain-stimulation reward
Guidance for the clinical evaluation of traditional Chinese medicine-induced liver injury Issued by China Food and Drug Administration
期刊论文
2019, 卷号: 0, 期号: 3, 页码: 648-658
作者:
Xiaohe Xiao[1]
;
Jianyuan Tang[2]
;
Yimin Mao[3]
;
Xiuhui Li[4]
;
Jiabo Wang[1]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/12/16
TCM
PTA
Guidance
for
the
clinical
evaluation
of
traditional
Chinese
medicine-induced
liver
injury
Issued
by
China
Food
and
Drug
Administration
China
China National Medical Products Administration approval summary: anlotinib for the treatment of advanced non-small cell lung cancer after two lines of chemotherapy
期刊论文
2019, 卷号: 39, 期号: 1, 页码: 36
作者:
Zhou, Ming
;
Chen, Xiaoyuan
;
Zhang, Hong
;
Xia, Lin
;
Tong, Xin
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/01/03
Advanced non-small cell lung cancer
Anlotinib
Anti-angiogenesis
Epidermal growth factor receptor
Activating anaplastic lymphoma kinase
Adverse drug reaction
National Medical Products Administration
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
Poly(amidoamine) Dendrimer as a Respiratory Nanocarrier: Insights from Experiments and Molecular Dynamics Simulations
期刊论文
LANGMUIR, 2019, 卷号: 35, 页码: 5364-5371
作者:
Tian, Fujia
;
Lin, Xubo
;
Valle, Russell P.
;
Zuo, Yi Y.
;
Gu, Ning
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/30
Controlled drug delivery
Dendrimers
Expansion
Molecular dynamics
Phospholipids
Physiology
Surface active agents
Targeted drug delivery
Coarse-grained molecular dynamics simulations
Dipalmitoyl phosphatidylcholine
Environmental temperature
Molecular dynamics simulations
Polyamidoamine dendrimers
Pulmonary drug delivery
Pulmonary surfactants
Systemic administration
Monolayers
Recent Advances in Drug Development and Regulatory Science in China
期刊论文
THERAPEUTIC INNOVATION & REGULATORY SCIENCE, 2018, 卷号: 52, 期号: 6
作者:
Chen, Jie
;
Zhao, Naiqing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
China Food and Drug Administration (CFDA)
Clinical trials
New drug application
Statistical guideline
Multi-regional clinical trials
Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 页码: 14851-14859
作者:
Li, Mingle
;
Xia, Jin
;
Tian, Ruisong
;
Wang, Jingyun
;
Fan, Jiangli
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/02
Cell death
Diseases
Infrared devices
Tumors, Cancer cell apoptosis
Hypoxic environments
Intravenous administration
Near infrared light
Personalized medicines
Photodynamic therapy (PDT)
Radical generation mechanisms
Therapeutic efficacy, Photodynamic therapy, antineoplastic agent
biotin
oxygen
superoxide, antihypoxia activity
apoptosis
Article
cancer cell
cancer inhibition
cancer tissue
cell transport
coculture
disease severity
dose response
drug activity
drug cytotoxicity
drug synthesis
human
in vitro study
in vivo study
ligand binding
neoplasm
nonhuman
patent
personalized medicine
photodynamic therapy
photoreactivity
radiation dose
rejuvenation
tumor ablation
tumor hypoxia
De Novo Design of Phototheranostic Sensitizers Based on Structure-Inherent Targeting for Enhanced Cancer Ablation
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 页码: 15820-15826
作者:
Li, Mingle
;
Long, Saran
;
Kang, Yao
;
Guo, Lianying
;
Wang, Jingyun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
Biocompatibility
Diagnosis
Diseases
Energy transfer
Forster resonance energy transfer
Infrared devices, Amplified light
Cancer diagnosis
Cellular uptake
Intravenous injections
Orders of magnitude
Photodynamic therapy (PDT)
Therapeutic index
Tumor targeting, Photodynamic therapy, article
biocompatibility
cancer model
controlled study
energy transfer
gene amplification
human
in vitro study
in vivo study
infrared radiation
intravenous drug administration
light harvesting system
mitochondrion
photosensitization
therapeutic index
tumor ablation
Functional nanocarrier for drug and gene delivery via local administration in mucosal tissues
期刊论文
Nanomedicine, 2018, 卷号: Vol.13 No.1, 页码: 20
作者:
Wang, L.a
;
Zhou, Y.b
;
Wu, M.a
;
Li, X.a
;
Gong, X.b
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/21
drug and gene delivery
local administration
mucoadhesive nanoparticles
mucus
mucus barrier properties
mucus-penetrating particles
nano-delivery system
Interventions for reducing inflammation in familial Mediterranean fever
期刊论文
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2018, 卷号: No.10
作者:
Wu, Bin
;
Xu, Ting
;
Li, Youping
;
Yin, Xi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/28
Administration,
Oral
Colchicine
[administration
&
dosage
adverse
effects]
Familial
Mediterranean
Fever
[drug
therapy]
Injections,
Subcutaneous
Plant
Extracts
[administration
&
dosage
adverse
effects]
Randomized
Controlled
Trials
as
Topic
Recombinant
Fusion
Proteins
[administration
&
dosage
adverse
effects]
Adolescent
Adult
Child
Child,
Preschool
Female
Humans
Male
Middle
Aged
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