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生态环境研究中心 [12]
北京大学 [4]
厦门大学 [3]
上海药物研究所 [3]
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期刊论文 [40]
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Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts
Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78
作者:
Huang, Chun-Hua
;
Xu, Dan
;
Qin, Li
;
Tang, Tian-Shu
;
Shan, Guo-Qiang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/09/14
N-alkyl hydroxamic acids
N-centered radicals
Chlorinated quinones
Carbon-nitrogen bonding conjugate
DNA adducts
Recent developments in DNA adduct analysis using liquid chromatography coupled with mass spectrometry
期刊论文
2019
作者:
Tang Yu
;
Zhang Jin-Lan
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  |  
浏览/下载:107/0
  |  
提交时间:2020/01/03
DNA adductomics
DNA adducts
LC-MS
analytical methods
recent developments
Simultaneous quantitation of 14 DNA alkylation adducts in human liver and kidney cells by UHPLC-MS/MS: Application to profiling DNA adducts of genotoxic reagents
期刊论文
2019, 卷号: 166, 页码: 387-397
作者:
Tang, Yu
;
Wang, Zhe
;
Li, Menglin
;
Zhang, Ruiping
;
Zhang, Jinlan
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  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
DNA adducts
UHPLC-MS/MS
Cell model
Genotoxic reagents
Method development
Site-Selective Labeling of Chromium as a Quencher on DNA for Molecular Beacons
期刊论文
ChemPlusChem, 2017, 卷号: Vol.82 No.9, 页码: 1224-1230
作者:
Ma, H.
;
Li, W.
;
Zhou, W.
;
Liu, J.
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/31
chromium
DNA adducts
fluorescence quenchers
nucleic acids
transition metals
Site-Selective Labeling of Chromium(III) as a Quencher on DNA for Molecular Beacons
期刊论文
ChemPlusChem, 2017, 卷号: Vol.82 No.9, 页码: 1224-1230
作者:
Ma, H
;
Li, W
;
Zhou, WH
;
Liu, JW
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/31
chromium
DNA adducts
fluorescence quenchers
nucleic acids
transition metals
Aldo-keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds
期刊论文
Molecular Carcinogenesis, 2017, 卷号: 56, 期号: 1, 页码: 118-129
作者:
Zu, Xuyu*
;
Yan, Ruilan
;
Pan, Jishen
;
Zhong, Linlin
;
Cao, Yu
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
*AKR1B10
*DNA damage
*acrolein-deoxyguanosine adducts
*colorectal cancer
*electrophilic carbonyl compounds
Aldo-keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds
期刊论文
Molecular Carcinogenesis, 2017, 卷号: 56, 期号: 1, 页码: 118-129
作者:
Zu, Xuyu*
;
Yan, Ruilan
;
Pan, Jishen
;
Zhong, Linlin
;
Cao, Yu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/27
*AKR1B10
*DNA damage
*acrolein-deoxyguanosine adducts
*colorectal cancer
*electrophilic carbonyl compounds
Novel adducts from the reaction of 1-chloro-3-buten-2-one with 2 '-deoxyguanosine. Structural characterization and potential as tools to investigate 1,3-butadiene carcinogenicity
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2015, 卷号: 226, 页码: 40-48
作者:
Zheng, Jin[1]
;
Li, Yan[2]
;
Yu, Ying-Xin[3]
;
An, Jing[4]
;
Zhang, Xin-Yu[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/26
1
3-Butadiene
1-Chloro-3-buten-2-one
2′-Deoxyguanosine
Bioactivation
Biomarkers
DNA adducts
Dual-Functional Analogous cis-Platinum Complex with High Antitumor Activities and Two-Photon Bioimaging
期刊论文
Biochemistry, 2015, 卷号: Vol.54 No.13, 页码: 2177-2180
作者:
Yang,Jiaxiang
;
Jin,Bao-Kang
;
Hu,Guiju
;
Wu,Jieying
;
Zhou,Hongping
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/22
IN-VIVO
PLATINUM COMPLEXES
FLUORESCENT-PROBES
DNA-ADDUCTS
LIVE CELLS
ONE-PHOTON
MICROSCOPY
LUMINESCENCE
ABSORPTION
EMISSION
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