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Chinese herb pair Paeoniae Radix Alba and Atractylodis Macrocephalae Rhizoma suppresses LPS-induced inflammatory response through inhibiting MAPK and NF-κB pathway. 期刊论文
Chinese Medicine, 2019, 卷号: Vol.14 No.1
作者:  Zhou, Yangyang;  Tao, Hongxun;  Wang, Anqi;  Zhong, Zhangfeng;  Wu, Xu
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/17
Voltammetric determination of attomolar levels of a sequence derived from the genom of hepatitis B virus by using molecular beacon mediated circular strand displacement and rolling circle amplification 期刊论文
MICROCHIMICA ACTA, 2018, 卷号: 185, 期号: 3
作者:  Huang, Shan;  Feng, Mengmeng;  Li, Jiawen;  Liu, Yi;  Xiao, Qi
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/05
Label-free molecular beacon for real-time monitoring of DNA polymerase activity. 期刊论文
Anal Bioanal Chem., 2016, 卷号: Vol.408 No.12, 页码: 3275-3280
作者:  Ma, Changbei;  Liu, Haisheng;  Wang, Jun;  Jin, Shunxin;  Wang, Kemin
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/31
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载：28/0  |  提交时间：2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
An Intron Mutation in the ACVRL1 May Be Associated with a Transcriptional Regulation Defect in a Chinese Family with Hereditary Hemorrhagic Telangiectasia 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 2, 页码: e58031
作者:  Yu, Qian;  Shen, Xiao-Hui;  Li, Ying;  Li, Rui-Juan;  Li, Ji
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/03
Toxoplasma gondii: protective effect of an intranasal SAG1 and MIC4 DNA vaccine in mice. 期刊论文
Experimental parasitology, 2009, 卷号: 122, 期号: 3, 页码: 226-232
作者:  Wang H;  He S;  Yao Y;  Cong H;  Zhao H
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/26
Continuous monitoring of restriction endonuclease cleavage activity by universal molecular beacon light quenching coupled with real-time polymerase chain reaction 期刊论文
分析生物化学, 2008
Li, Xiaomin; Song, Chen; Zhao, Meiping; Li, Yuanzong
收藏  |  浏览/下载：2/0  |  提交时间：2015/11/10
Electrochemical immunosensor of platelet-derived growth factor with aptamer-primed polymerase amplification 期刊论文
Analytical Biochemistry, 2008, 卷号: Vol.382 No.1, 页码: 16-22
作者:  Huang, Y;  Nie, XM;  Gan, SL;  Jiang, JH;  Shen, GL
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/13
A modified single-tube one-step product-enhanced reverse transcriptase (mSTOS-PERT) assay with heparin as DNA polymerase inhibitor for specific detection of RTase activity 期刊论文
JOURNAL OF CLINICAL VIROLOGY, 2006, 卷号: 37, 期号: 4
作者:  Fan, Xiao-Yong;  Lu, Guo-Zhen;  Wu, Li-Na;  Chen, Jing-Hua;  Xu, Wen-Qing
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/27

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