×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
南华大学 [3]
厦门大学 [3]
上海神经科学研究所 [2]
山东大学 [2]
武汉轻工大学 [2]
河北省人民医院 [2]
更多...
内容类型
期刊论文 [23]
学位论文 [1]
发表日期
2018 [2]
2017 [4]
2016 [5]
2015 [2]
2014 [3]
2012 [1]
更多...
学科主题
Neuroscien... [1]
Science & ... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共24条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
A Nestin-Cyclin-Dependent Kinase 5-Dynamin-Related Protein 1 Axis Regulates Neural Stem/Progenitor Cell Stemness via a Metabolic Shift
期刊论文
STEM CELLS, 2018, 卷号: 36, 页码: 589-601
作者:
Wang, Jiancheng
;
Huang, Yinong
;
Cai, Jianye
;
Ke, Qiong
;
Xiao, Jiaqi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
Nestin
Mitochondria
Dynamin-related protein 1
Metabolism
Neural stem/progenitor cells
Cyclin-dependent kinase 5
Wnt-5a Promotes Neural Development and Differentiation by Regulating CDK5 via Ca2+/Calpain Pathway
期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: 51, 期号: 6, 页码: 2604-2615
作者:
Shu Yang[1]
;
Xiang Min[2]
;
Zhang Pei[3]
;
Qi Guangjian[4]
;
He Feng[5]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/24
Ca2+/calpain signaling
Cyclin-dependent kinase 5
Development
Differentiation
Wnt signaling
细胞周期素依赖蛋白激酶5促进肝细胞癌的侵袭与转移
学位论文
2017, 2016
赵文兴
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/06/20
肝细胞癌
细胞周期素依赖蛋白激酶5
迁移
侵袭
Hepatocellular Carcinoma
Cyclin dependent kinase 5
Migration
Invasion
Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 卷号: 36
作者:
Wang, Yitao
;
Qin, Xian
;
Guo, Tao
;
Liu, Pengpeng
;
Wu, Ping
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Hepatocellular carcinoma (HCC)
Cyclin dependent Kinase 16 (CDK16)
Epithelial mesenchymal transition (EMT)
E2F1 transcription factor
miR-125b-5p
Cyclin-dependent kinase 5 controls vasculogenic mimicry formation in non-small cell lung cancer via the FAK-AKT signaling pathway
期刊论文
2017, 卷号: 492, 期号: 3, 页码: 447-452
作者:
Zhou, Xiaoshu
;
Gu, Runxia
;
Han, Xiaoming
;
Wu, Gang
;
Liu, Junli
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Vasculogenic mimicry
Cyclin-dependent kinase 5
Non-small cell lung cancer
Tumor plasticity
FAK
Regulation of thin recipe of Buyang Huanwudecoction on Cdk5 expression of rats after cerebral ischemia
期刊论文
Chinese Pharmacological Bulletin, 2017, 卷号: Vol.33 No.8, 页码: 1176-1181
作者:
Liu Fang
;
Wang Yuhong
;
Shao Le
;
Xia Xiangyi
;
She Yan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/31
Buyang Huanwu decoction
thin recipe of Buyang Huanwu decoction
middle cerebral artery occlusion(MCAO)
cyclin-dependent kinase 5(Cdk5)
cerebral ischemia
hippocampus
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
The mechanism of action of FXR1P-related miR-19b-3p in SH-SY5Y
期刊论文
Gene, 2016, 卷号: 588, 期号: 1, 页码: 62-68
作者:
Ma, Yun*
;
Tian, Shuai
;
He, Shuya*
;
Chen, Qiong
;
Wang, Zongbao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/27
mRNA
messenger ribonucleic acid
miRNA
micro ribonucleic acid
TNF-α
tumor necrosis factor-alpha
SH-SY5Y
cells SH-SY5Y neuroblastoma cells
Ago2
Argonaute 2
USP32
ubiquitin specific peptidase 32
RAB18
member RAS oncogene family
Dusp6
dual specificity phosphatase 6
Cdkn1a
cyclin-dependent kinase inhibitor 1A
Bcl-2
B-cell lymphoma-2
FMRP
fragile X mental retardation protein
FXR1P
fragile X-related 1 protein
FXR2P
fragile X-related 2 protein
3′UTR
3′untranslated regions
CDS
coding sequence
FACS
fluorescence activated cell sorter
PMSF
phenylmethanesulfonyl fluoride
SDS-PAGE
sodium dodecyl sulfate-polyacrylamide gel electrophoresis
ANOVA
analysis of variance
SD
standard deviation
PCR
polymerase chain reaction
miR-19b
FXR1
RAB18
USP32
Dusp6
The mechanism of action of FXR1P-related miR-19b-3p in SH-SY5Y
期刊论文
Gene, 2016, 卷号: 588, 期号: 1, 页码: 62-68
作者:
Ma, Yun*
;
Tian, Shuai
;
He, Shuya*
;
Chen, Qiong
;
Wang, Zongbao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/27
mRNA
messenger ribonucleic acid
miRNA
micro ribonucleic acid
TNF-α
tumor necrosis factor-alpha
SH-SY5Y
cells SH-SY5Y neuroblastoma cells
Ago2
Argonaute 2
USP32
ubiquitin specific peptidase 32
RAB18
member RAS oncogene family
Dusp6
dual specificity phosphatase 6
Cdkn1a
cyclin-dependent kinase inhibitor 1A
Bcl-2
B-cell lymphoma-2
FMRP
fragile X mental retardation protein
FXR1P
fragile X-related 1 protein
FXR2P
fragile X-related 2 protein
3′UTR
3′untranslated regions
CDS
coding sequence
FACS
fluorescence activated cell sorter
PMSF
phenylmethanesulfonyl fluoride
SDS-PAGE
sodium dodecyl sulfate-polyacrylamide gel electrophoresis
ANOVA
analysis of variance
SD
standard deviation
PCR
polymerase chain reaction
miR-19b
FXR1
RAB18
USP32
Dusp6
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells
期刊论文
Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, 卷号: 23, 期号: 13, 页码: 1555-1565
作者:
Chen, Xin
;
Wu, Qiu-Shuang
;
Meng, Fan-Cheng
;
Tang, Zheng-Hai
;
Chen, Xiuping
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/27
Panacis Japonici Rhizoma
Chikusetsusaponin IVa methyl ester
Ovarian cancer
Cell cycle arrest
Apoptosis
Metastasis
Bcl-2
B-cell lymphoma 2
CC
column chromatography
CDK
cyclin-dependent kinase
DMEM
Dulbecco's modified Eagle's medium
DMSO
dimethyl sulfoxide
FBS
fetal bovine serum
GAPDH
Glyceraldehyde 3-phosphate dehydrogenase
Hoechst 33342
2′-[4-ethoxyphenyl]-5-[4-methyl-1-piperazinyl]-2,5′-bi-1H-benzimidazole trihydrochloride trihydrate
JC-1
5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimi-dazolylcarbocyanine iodide
MMP
matrix metalloproteinase
MTT
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide
PARP
Poly (ADP-ribose) polymerase
PBS
phosphate-buffered saline
PI
ropidium iodide
PJR
Panacis Japonici Rhizoma
SD
standard deviation
©版权所有 ©2017 CSpace - Powered by
CSpace