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科研机构
山东大学 [3]
中国科学院大学 [1]
湖南农业大学 [1]
内容类型
期刊论文 [5]
发表日期
2019 [2]
2017 [1]
2016 [1]
2003 [1]
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Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:
Yevglevskis, Maksims
;
Nathubhai, Amit
;
Wadda, Katty
;
Lee, Guat L.
;
Al-Rawi, Suzanne
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/11
alpha-Methylacyl-CoA racemase (AMACR, P504S)
Branched-chain fatty acid
metabolism
Castrate-resistant prostate cancer (CRPC)
Drug
lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive
inhibition
Rational drug design
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
Bioorganic Chemistry, 2019, 卷号: 92
作者:
Yevglevskis M.
;
Nathubhai A.
;
Wadda K.
;
Lee G.L.
;
Al-Rawi S.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/11
Branched-chain fatty acid metabolism
Castrate-resistant prostate cancer (CRPC)
Drug lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive inhibition
Rational drug design
Structure-activity relationships
α-Methylacyl-CoA racemase (AMACR, P504S)
Human fetal intestinal epithelial cells metabolize and incorporate branched chain fatty acids in a structure specific manner
期刊论文
Prostaglandins, leukotrienes, and essential fatty acids, 2017, 卷号: 116, 页码: 32-39
作者:
Liu, Lei
;
Wang, Zhen
;
Park, Hui Gyu
;
Xu, Chuang
;
Lawrence, Peter
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/23
BCFA
(branched-chain fatty acids)
CE
(cholesterol esters)
DAG
(diacylglycerol)
FAME
(fatty acid methyl esters)
GI
(gastrointestinal)
MAG
(monoacylglycerol)
NEC
(necrotizing enterocolitis)
PL
(phospholipids)
SFA
(saturated fatty acids)
TAG
( triacylglycerol)
Lipids
Phospholipids
Diacylglycerol
Triglycerides
Free fatty acids
Cholesterol esters
Metabolism
Intestine
Effects of supplementation with branched-chain amino acids to low-protein diets on expression of genes related to lipid metabolism in skeletal muscle of growing pigs
期刊论文
Amino acids, 2016, 卷号: 48, 期号: 9, 页码: 2131-2144
作者:
Duan, Yehui
;
Duan, Yangmiao
;
Li, Fengna
;
Li, Yinghui
;
Guo, Qiuping
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/05/09
Branched-chain amino acid ratio
Fatty acid composition
Lipid metabolism
Skeletal muscles
Growing pigs
Branched chain amino acid imbalance selectively inhibits the growth of gastric carcinoma cells in vitro
期刊论文
Nutrition Research, 2003, 卷号: 23, 期号: 9, 页码: 1279-1290
作者:
Sun XY
;
Zhang N
;
Li K
;
Liu M
;
Zhi XT
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/01/14
Amino acid imbalance
Branched chain amino acid
Cancer
Nutrition
Total parenteral-nutrition
Glucose-metabolism
Valine metabolism
Cancer cachexia
Fatty liver
Leucine
Tumor
Rats
Requirements
Support
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