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Arabinogalactan Proteins Are the Possible Extracellular Molecules for Binding Exogenous Cerium in the Acidic Environment Outside Plant Cells. 期刊论文
Frontiers in plant science, 2019, 卷号: Vol.10, 页码: 153
作者:  Qing Yang;  Lihong Wang;  Jingfang He;  Haiyan Wei;  Zhenbiao Yang
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/17
Enhanced reversible lithium ion storage in stable 1T@2H WS2 nanosheet arrays anchored on carbon fiber 期刊论文
ELECTROCHIMICA ACTA, 2018, 卷号: 259, 页码: 1-8
作者:  Wang, Tailin;  Sun, Changlong;  Yang, Mingzhi;  Zhang, Lei;  Shao, Yongliang
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/11
Construction of Core-Shell NiMoO4@Ni-Co-S Nanorods as Advanced Electrodes for High-Performance Asymmetric Supercapacitors 期刊论文
ACS Applied Materials and Interfaces, 2018, 卷号: 10, 期号: 5, 页码: 4662-4671
作者:  Chen, Chao;  Yan, Dan;  Luo, Xin;  Gao, Wenjia;  Huang, Guanjie
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/23
新疆某公司域名系统优化与实现 学位论文
2015, 2014
哈木拉提
收藏  |  浏览/下载:2/0  |  提交时间:2016/01/12
基于MEMS力传感器的智能绑带装置研制 期刊论文
自动化与仪表, 2014
陈得民; 张威; 周浩南; 沈唯真
收藏  |  浏览/下载:2/0  |  提交时间:2015/11/11
长牡蛎贝壳形成相关蛋白及其基因的研究 学位论文
硕士: 中国科学院研究生院, 2013
作者:  宋小瑞
收藏  |  浏览/下载:116/0  |  提交时间:2014/08/08
Delivery system for DNAzymes using arginine-modified hydroxyapatite nanoparticles for therapeutic application in a nasopharyngeal carcinoma model 期刊论文
International Journal of Nanomedicine, 2013, 卷号: 8, 期号: 1, 页码: 3107-3118
作者:  Chen, Yan;  Yang, Lifang*;  Huang, Suping;  Li, Zhi;  Zhang, Lu
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/03
DNAzymes are synthetic  single-stranded  catalytic nucleic acids that bind and cleave target mRNA in a sequence-specific manner  and have been explored for genotherapeutics. One bottleneck restricting their application is the lack of an efficient delivery system. As an inorganic nanomaterial with potentially wide application  nanohydroxyapatite particles (nHAP) have attracted increasing attention as new candidates for nonviral vectors. In this study  we developed an nHAP-based delivery system and explored its cellular uptake mechanisms  intracellular localization  and biological effects. Absorption of arginine-modified nanohydroxyapatite particles (Arg-nHAP) and DZ1 (latent membrane protein 1 [LMP1]-targeted) reached nearly 100% efficiency under in vitro conditions. Using specific inhibitors  cellular uptake of the Arg-nHAP/DZ1 complex was shown to be mediated by the energy-dependent endocytosis pathway. Further  effective intracellular delivery and nuclear localization of the complex was confirmed by confocal microscopy. Biologically  the complex successfully downregulated the expression of LMP1 in nasopharyngeal carcinoma cells. In a mouse tumor xenograft model  the complex was shown to be delivered efficiently to tumor tissue  downregulating expression of LMP1 and suppressing tumor growth. These results suggest that Arg-nHAP may be an efficient vector for nucleic acid-based drugs with potential clinical application.  
Tip-to-tip interaction in the crystal packing of PACSIN 2 is important in regulating tubulation activity 期刊论文
protein cell, 2013
Bai, Xiaoyun; Zheng, Xiaofeng
收藏  |  浏览/下载:4/0  |  提交时间:2015/11/13
Comprehensive Assessment Method Based on Blind Information Theory in Highway Tunnel Construction 会议论文
Changsha, PEOPLES R CHINA, SEP 15-16, 2012
作者:  Ye, Fangzheng;  Zhan, Huiming;  Su, Shuxun;  Gong, Wenhui
收藏  |  浏览/下载:21/0  |  提交时间:2018/06/05
A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer-Protein Interactions 期刊论文
http://dx.doi.org/10.1021/ja310428s, 2012
Han, Da; Zhu, Zhi; Wu, Cuichen; Peng, Lu; Zhou, Leiji; Gulbakan, Basri; Zhu, Guizhi; Williams, Kathryn R.; Tan, Weihong; 朱志
收藏  |  浏览/下载:56/0  |  提交时间:2015/07/22


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