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北京大学 [13]
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复旦大学上海医学院 [2]
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期刊论文 [27]
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2015 [3]
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物理化学 [1]
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Cyclooxygenase-2 short hairpin rna improves hepatic fibrosis by regulating the TGFBL/SMADS signal transduction pathway
期刊论文
ACTA MEDICA MEDITERRANEA, 2018, 卷号: 34, 期号: 2, 页码: 495-498
作者:
Fu, Nian
;
Liao, Hong-Wu
;
Wen, Luo
;
Zhou, Xu
;
Peng, Meng-Jie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
COX-2
Short hairpin RNA
Hepatic fibrosis
Transforming growth factor-beta
Smads
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
期刊论文
Gastroenterology, 2017, 卷号: 153, 期号: 5, 页码: 1429-1443.e5
作者:
Xie, Yangchun
;
Zhu, Shan
;
Zhong, Meizuo
;
Yang, Minghua
;
Sun, Xiaofan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Regulated Cell Death
Antitumor Immunity
HMGB1
ATP
AURKA
aurora kinase A
DAMPs
damage-associated molecular patterns
GSK3β
glycogen synthase kinase 3 beta
HEK293
human embryonic kidney 293
HPDE
human pancreatic duct epithelial cell
ICD
immunogenic cell death
IFN
interferon
MEF
mouse embryonic fibroblast
MLKL
mixed lineage kinase domain-like
PDAC
pancreatic ductal adenocarcinoma cancer
RIPK
receptor interacting serine/threonine kinase
shRNA
short hairpin RNA
TNFR1
tumor necrosis factor receptor 1
WT
wild type
Growth inhibition of human gastric adenocarcinoma cells in vitro by STO-609 is independent of calcium/calmodulin-dependent protein kinase kinase-beta and adenosine monophosphate-activated protein kinase
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2016, 卷号: 8, 期号: 2
作者:
Ma, Zhiming
;
Wen, Dacheng
;
Wang, Xudong
;
Yang, Longfei
;
Liu, Tianzhou
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Adenocarcinoma
apoptosis
AMP-activated protein kinase
calcium/calmodulin-dependent protein kinase kinase-beta
gastric carcinoma
short hairpin RNA
Salt-inducible Kinase (SIK1) regulates HCC progression and WNT/β-catenin activation
期刊论文
Journal of Hepatology, 2016, 卷号: 64, 期号: 5, 页码: 1076-1089
作者:
Qu, Chao
;
He, De
;
Lu, Xiaoling
;
Dong, Lihua
;
Zhu, Yuekun
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/03
ChIP
chromatin immunoprecipitation
DFS
disease-free survival
EGF
epidermal growth factor
EMT
epithelial-mesenchymal transition
GSK-3β
glycogen synthase kinase-3β
HCC
hepatocellular carcinoma
HDAC3
histone deacetylase 3
IF
immunofluorescence
IHC
immunohistochemistry
NCoR
nuclear receptor corepressor
OS
overall survival
PCR
polymerase chain reaction
TBL1
transducin-beta-like protein 1
TBLR1
transducing-beta-like 1 X-linked receptor 1
TF
transcriptional factor
shSIK1
small hairpin RNA targeting SIK1
Salt-inducible kinase 1
Twist1
Epithelial-mesenchymal transition
β-catenin
Silencing mediator for retinoid
Thyroid receptors
Folding Simulations of an alpha-Helical Hairpin Motif alpha t alpha with Residue-Specific Force Fields
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2016
Zeng, Juan
;
Jiang, Fan
;
Wu, Yun-Dong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
DE-NOVO DESIGN
EXCHANGE MOLECULAR-DYNAMICS
LINEAR CONSTRAINT SOLVER
MONTE-CARLO SIMULATIONS
BETA-HAIRPIN
ENGRAILED HOMEODOMAIN
SECONDARY STRUCTURE
AQUEOUS-SOLUTION
BUNDLE PROTEIN
HYDROGEN-BONDS
11 beta-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid- induced insulin resistance and lipolysis in mouse abdominal adipose tissue
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2015, 卷号: 308, 期号: 1
作者:
Wang, Ying
;
Yan, Chaoying
;
Liu, Limei
;
Wang, Wei
;
Du, Hanze
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
adipose tissue
insulin signaling
lipolysis
hexose-6-phosphate dehydrogenase
glucocorticoid
11 beta-hydroxysteroid dehydrogenase type 1
short-hairpin RNA
From Thermodynamics to Kinetics: Enhanced Sampling of Rare Events
期刊论文
ACCOUNTS OF CHEMICAL RESEARCH, 2015
Yang, Lijiang
;
Liu, Cheng-Wen
;
Shao, Qiang
;
Zhang, Jun
;
Gao, Yi Qin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
ACCELERATED MOLECULAR-DYNAMICS
HYBRID DENSITY FUNCTIONALS
ION MOBILITY SPECTROMETRY
HELIX BUNDLE PROTEINS
BETA-HAIRPIN PEPTIDE
DISPERSION CORRECTIONS
POTENTIAL-ENERGY
REPLICA-EXCHANGE
COMPLEX-SYSTEMS
WATER CLUSTERS
Residue-Specific Force Field Based on Protein Coil Library. RSFF2: Modification of AMBER ff99SB
期刊论文
journal of physical chemistry b, 2015
Zhou, Chen-Yang
;
Jiang, Fan
;
Wu, Yun-Dong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
MOLECULAR-DYNAMICS SIMULATIONS
BETA-HAIRPIN FORMATION
PARTICLE MESH EWALD
FOLDING SIMULATIONS
AMINO-ACIDS
SIDE-CHAIN
ALANINE RESIDUES
UNFOLDED STATE
HELIX
PEPTIDES
The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of beta-hairpin
期刊论文
SCIENCE CHINA-CHEMISTRY, 2014, 卷号: 57, 期号: 2, 页码: 307-313
作者:
Chen BaoEn
;
Gan JianHua
;
Yang CaiGuang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
DNA repair
ALKBH2
chemical cross-linking
beta-hairpin motif
damage detection
Discriminating trpzip2 and trpzip4 peptides' folding landscape using the two-dimensional infrared spectroscopy: A simulation study
期刊论文
journal of chemical physics, 2014
Wu, Tianmin
;
Zhang, Ruiting
;
Li, Huanhuan
;
Yang, Lijiang
;
Zhuang, Wei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/11
BETA-HAIRPIN PEPTIDE
FREE-ENERGY LANDSCAPE
AMIDE-I MODES
MOLECULAR-DYNAMICS
TRANSITION-STATE
VIBRATIONAL SPECTROSCOPY
CONFORMATIONAL DYNAMICS
FORCE-FIELDS
LIQUID WATER
PROTEINS
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