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山东大学 [4]
厦门大学 [2]
中南大学 [2]
武汉大学 [2]
兰州理工大学 [1]
西安交通大学 [1]
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期刊论文 [15]
学位论文 [2]
会议论文 [1]
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2018 [1]
2017 [2]
2016 [3]
2015 [1]
2014 [3]
2013 [4]
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Peptide-Induced Self-Assembly of Therapeutics into a Well-Defined Nanoshell with Tumor-Triggered Shape and Charge Switch
期刊论文
Chemistry of Materials, 2018, 卷号: 30, 页码: 7034-7046
作者:
He, Wangxiao
;
Yan, Jin
;
Jiang, Wei
;
Li, Shichao
;
Qu, Yiping
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/11/26
Acidic microenvironment
Anti-cancer therapies
Intracellular accumulation
Long circulations
Macromolecular drugs
Macromolecular therapeutics
Therapeutic peptides
Tumor suppressors
核受体Nur77、RXR的凋亡通路及调控
学位论文
2017, 2010
刘婕
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/06/20
孤儿受体Nur77
Bcl - 2
Bax
紫草素衍生物
癌细胞凋亡
tRXRα
肿瘤坏死因子(TNFα)
Akt
p85
抗肿瘤药物
Orphan receptor Nur77
Bcl-2
Bax
Shikonin analogues
Apoptosis
tRXRα
Tumor necrosis factor-α (TNFα)
Akt
p85
Anti-cancer drugs
Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 185-206
作者:
Li, Xiaoyang
;
Zhang, Yingjie
;
Jiang, Yuqi
;
Wu, Jingde
;
Inks, Elizabeth S.
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/12
HDACs
HDACIs
Benzamides
Anti-tumor drugs
In vivo oral activity
以PD-1为靶点的抗肿瘤药物专利发展状况分析
期刊论文
医学信息, 2016, 卷号: 29, 期号: 31
作者:
刘海杰[1]刘春侠[2]王艳卓[1]于双成[1]李正红[3]
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  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
PD-1
抗肿瘤药物
专利分析
PD-1
Anti-tumor drugs
Patent analysis
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling
期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:
Liu, Jianxin
;
Tang, Jinshan
;
Zuo, Yihan
;
Yu, Yang
;
Luo, Pei
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  |  
浏览/下载:19/0
  |  
提交时间:2019/12/03
NO
nitric oxide
PGE2
prostaglandin E2
NSAIDs
non-steroidal anti-inflammatory drugs
qRT-PCR
quantitative real-time polymerase chain reaction
LPS
lipopolysaccharide
IFN-γ
interferon γ
G-CSF
granulocyte colony stimulating factor
TNF-α
tumor necrosis factor-α
IL-1β
interleukin-1β
IL-6
interleukin-6
MCP-1
monocyte chemoattractant protein-1
NF-κB
Nuclear factor-κB
IκB
inhibitory protein
IKK
IκB kinase
RPS3
ribosomal protein S3
iNOS
inducible nitric oxide synthase
COX-2
cyclooxygenase-2
PGESs
prostaglandin E2 synthases
mPGES-1
microsomal prostaglandin synthetase-1
mPGES-2
microsomal prostaglandin E synthase-2
cPGES
cytosolic prostaglandin E synthase
MAPK
mitogen-activated protein kinases
ERK
extracellular signal-regulated kinase
JNK
c- Jun N-terminal kinase
PGI2
prostacyclin I2
PGD2
prostaglandin D2
PGF2α
prostaglandin F2α
TXA2
thromboxane A2
Stauntoside B (PubChem CID: 101010462)
Stauntoside B
Cynanchi stauntonii
Lipopolysaccharide
Anti-inflammatory activity
NF-κB
MAPK
Investigations on the interactions between naphthalimide-based anti-tumor drugs and human serum albumin by spectroscopic and molecular modeling methods
期刊论文
LUMINESCENCE, 2016, 卷号: 31, 期号: 1
作者:
Cheng, Huiyuan
;
Zou, Ting
;
Xu, Yongliang
;
Wang, Ying
;
Wu, Aibin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
human serum albumin
naphthalimide-based anti-tumor drugs
fluorescence quenching
circular dichroism
molecular modeling
Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 89, 页码: 628-637
作者:
Li, Xiaoyang
;
Hou, Jinning
;
Li, Xiaoguang
;
Jiang, Yuqi
;
Liu, Xueliang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
HDACs
HDACIs
Anti-tumor drugs
Antiproliferative activity
In vivo
oral activity
Hepatitis reactivation in patients with rheumatic diseases after immunosuppressive therapy-a report of long-term follow-up of serial cases and literature review
期刊论文
CLINICAL RHEUMATOLOGY, 2014, 卷号: 33, 期号: 4
作者:
Xuan, Dandan
;
Yu, Yiqi
;
Shao, Linyun
;
Wang, Jiali
;
Zhang, Wenhong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Disease-modifying anti-rheumatic drugs
Hepatitis B
Rheumatic disease
Steroid
Tumor necrosis factor-alpha-blocking agent
A novel targeting drug carrier to deliver chemical bonded and physical entrapped anti-tumor drugs
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2014, 卷号: 466, 期号: 1-2
作者:
Huang, Ling
;
Song, Jinchun
;
Chen, Bangyin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Targeting
Drug carrier
Entrapped
Anti-tumor drugs
Sustained release of PTX-incorporated nanoparticles synergized by burst release of DOX.HCl from thermosensitive modified PEG/PCL hydrogel to improve anti-tumor efficiency
期刊论文
2014, 卷号: 62, 页码: 267-273
作者:
Xu, Shuxin
;
Wang, Weiwei
;
Li, Xijing
;
Liu, Jianping
;
Dong, Anjie
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
Thermo-sensitive
Hydrogel
Nanoparticle
Dual drugs
Synergy
Anti-tumor
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