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复旦大学上海医学院 [51]
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S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:
Xiang, Hao-Yue
;
Wang, Xiang
;
Chen, Yan-Hong
;
Zhang, Xi
;
Tan, Cun
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  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
PI3K
Pyrrolo[2,1-f][1,2,4]triazine
Anti-cancer
Target therapy
Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 14
作者:
Zhao, Yanmei
;
Xu, Lei
;
Zhang, Jiankang
;
Zhang, Mengmeng
;
Lu, Jingyi
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  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Proteasome inhibitor
Piperidine
Peptidyl
Anti-cancer
SAR
Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15
作者:
Yu, Qing
;
Sun, Yi
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  |  
浏览/下载:23/0
  |  
提交时间:2021/03/15
anti-cancer drug
cullin-RING E3 ligases
natural product
high-throughput screen
neddylation
small-molecule inhibitors
Nanovaccine's rapid induction of anti-tumor immunity significantly improves malignant cancer immunotherapy
期刊论文
NANO TODAY, 2020, 卷号: 35, 页码: 12
作者:
Zhang, Ling-xiao
;
Sun, Xia-mei
;
Jia, Ying-bo
;
Liu, Xiao-ge
;
Dong, Mingdong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/03/29
Malignant cancer immunotherapy
Layered double hydroxide based nanovaccine
Vaccination routes
Quick induction of anti-tumor immunity
Tumor-Activated Size-Enlargeable Bioinspired Lipoproteins Access Cancer Cells in Tumor to Elicit Anti-Tumor Immune Responses
期刊论文
ADVANCED MATERIALS, 2020, 页码: 11
作者:
Li, Jie
;
Wang, Hong
;
Wang, Yuqi
;
Gong, Xiang
;
Xu, Xiaoxuan
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  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
anti-tumor immune responses
cancer immunotherapy
lipoproteins
oxaliplatin
tumor targeting
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
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  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
Regulatory T Cells in Cancer Immunotherapy: Basic Research Outcomes and Clinical Directions
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2020, 卷号: 12, 页码: 10411-10421
作者:
Zeng, Guoming
;
Jin, Libo
;
Ying, Qinsi
;
Chen, Haojie
;
Thembinkosi, Murinda Charmaine
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/02/02
cancer immunotherapy
Treg cells
FoxP3
targeting Treg cells
anti-cancer
Regulatory T Cells in Cancer Immunotherapy: Basic Research Outcomes and Clinical Directions
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2020, 卷号: 12, 页码: 10411-10421
作者:
Zeng, Guoming
;
Jin, Libo
;
Ying, Qinsi
;
Chen, Haojie
;
Thembinkosi, Murinda Charmaine
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/02/02
cancer immunotherapy
Treg cells
FoxP3
targeting Treg cells
anti-cancer
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