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湖南大学 [2]
兰州理工大学 [1]
兰州大学 [1]
西北高原生物研究所 [1]
大连化学物理研究所 [1]
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期刊论文 [16]
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2023 [1]
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pharmacolo... [1]
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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
收藏
  |  
浏览/下载:238/0
  |  
提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis
Alantolactone exhibits selective antitumor effects in HELA human cervical cancer cells by inhibiting cell migration and invasion, G2/M cell cycle arrest, mitochondrial mediated apoptosis and targeting Nf-kB signalling pathway
期刊论文
JOURNAL OF BUON, 2019, 卷号: 24, 期号: 6, 页码: 2310-2315
作者:
Yibing Zhang
;
Zhao, Yong
;
Ran, Yongwang
;
Guo, Jianyou
;
Cui, Haifeng
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  |  
浏览/下载:16/0
  |  
提交时间:2020/02/29
alantolactone
apoptosis
cervical cancer
cytometry
cell cycle
Alantolactone promotes ER stress-mediated apoptosis by inhibition of TrxR1 in triple-negative breast cancer cell lines and in a mouse model.
期刊论文
Journal of cellular and molecular medicine, 2019
作者:
Yin Changtian
;
Dai Xuanxuan
;
Huang Xiangjie
;
Zhu Wangyu
;
Chen Xi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
ER-stress
ROS
Triple-negative
breast
cancer
TrxR1
alantolactone
Alantolactone promotes ER stress‐mediated apoptosis by inhibition of TrxR1 in triple‐negative breast cancer cell lines and in a mouse model
期刊论文
Journal of Cellular and Molecular Medicine, 2019, 卷号: Vol.23 No.3, 页码: 2194-2206
作者:
Changtian Yin
;
Xuanxuan Dai
;
Xiangjie Huang
;
Wangyu Zhu
;
Xi Chen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/17
alantolactone
ER‐stress
ROS
Triple‐negative
breast
cancer
TrxR1
Metabolism and pharmacokinetics of alantolactone and isoalantolactone in rats: Thiol conjugation as a potential metabolic pathway
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1072, 页码: 370-378
作者:
Zhou, Bailun
;
Ye, Ji
;
Yang, Niao
;
Chen, Liping
;
Zhuo, Zhiguo
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  |  
浏览/下载:44/0
  |  
提交时间:2019/06/20
Alantolactone
Isoalantolactone
Glutathione
Cysteine
Conjugation
Metabolism
Alantolactone, a sesquiterpene lactone, inhibits breast cancer growth by antiangiogenic activity via blocking VEGFR2 signaling
期刊论文
PHYTOTHERAPY RESEARCH, 2018, 卷号: 32, 期号: 4
作者:
Liu, Ya-Rong
;
Cai, Qin-Yi
;
Gao, Yun-Ge
;
Luan, Xin
;
Guan, Ying-Yun
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/06
Alantolactone
antiangiogenic cancer therapy
chick embryo chorioallantoic membrane
sesquiterpene lactone
VEGFR2
Bioavailability and pharmacokinetics of alantolactone from Inula helenium in rats following intravenous and oral administrations
期刊论文
Journal of Chinese Pharmaceutical Sciences, 2017, 卷号: 26, 期号: 4, 页码: 284-290
作者:
Zhang Xinguo
;
Liu Jinweng
;
Kou Fei
;
Wang Qianglin
;
Liu Ziyu
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/06/16
HPLC
Alantolactone
Pharmacokinetic
Bioavailability
HPLC
Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 102, 页码: 34-44
作者:
Zhang, JM
;
Li, Y
;
Duan, DZ
;
Yao, J
;
Gao, K
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/01/11
Thioredoxin reductase
Alantolactone
Oxidative stress
Redox regulation
Apoptosis
Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells
期刊论文
Journal of Hematology & Oncology, 2016, 卷号: Vol.9 No.1
作者:
Yahui Ding
;
Huier Gao
;
Yu Zhang
;
Ye Li
;
Neil Vasdev
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  |  
浏览/下载:3/0
  |  
提交时间:2019/02/27
Alantolactone
Acute myeloid leukemia stem cells
KG1a
Apoptosis
Obtaining alantolactone and isoalantolactone from Inula racemose Hook.f. by optimized supercritical fluid extraction
期刊论文
industrial crops and products, 2016, 卷号: 79, 页码: 63-69
作者:
Chi, Xiao-Feng
;
Yue, Hui-Lan
;
Zhao, Xiao-Hui
;
Hu, Feng-Zu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2016/12/19
Inula racemose Hook.f
Alantolactone
Isoalantolactone
Supercritical fluid extraction
Response surface methodology
Freezing
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