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上海药物研究所 [10]
山东大学 [4]
复旦大学上海医学院 [4]
昆明医科大学 [3]
北京大学 [1]
上海神经科学研究所 [1]
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期刊论文 [26]
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Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
The neuroprotective effect of deep brain stimulation at nucleus basalis of Meynert in transgenic mice with Alzheimer's disease
期刊论文
BRAIN STIMULATION, 2019, 卷号: 12, 期号: 1
作者:
Zhou, Zaiying
;
Huang, Dongya
;
Ma, Yu
;
Dai, Chuanfu
;
Ao, Qiang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/05
Alzheimer's disease
Deep brain stimulation
Nucleus basalis of Meynert
APP/PS1 transgenic mice
Morris water maze
Altered mitochondrial DNA methylation and mitochondrial DNA copy number in an APP/PS1 transgenic mouse model of Alzheimer disease
期刊论文
Biochemical and Biophysical Research Communications, 2019, 卷号: 520, 期号: 1, 页码: 41-46
作者:
Xu Y.
;
Xu L.
;
Han M.
;
Liu X.
;
Li F.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
12S rRNA gene
Alzheimer's disease
APP/PS1 transgenic mice
D-loop
Mitochondrial DNA copy number
Mitochondrial DNA methylation
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
Therapeutic effect of Rho kinase inhibitor FSD-C10 in a mouse model of Alzheimer's disease
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 5
作者:
Gu, Qing-Fang
;
Yu, Jie-Zhong
;
Wu, Hao
;
Li, Yan-Hua
;
Liu, Chun-Yun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Alzheimer's disease
APP/PS1transgenic mice
Rho kinase
FSD-C10
The A beta Containing Brain Extracts Having Different Effects in Alzheimer's Disease Transgenic Caenorhabditis elegans and Mice
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2018, 卷号: 10
作者:
Yang, Yufang
;
Wang, Mo
;
Yang, Ping
;
Wang, Zishan
;
Huang, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Alzheimer's disease
beta-amyloid
transgenic AD C. elegans
APP/PS1 transgenic mice
oral administration
RNA-sequencing (RNA-seq)
Multifaceted assessment of the APP/PS1 mouse model for Alzheimer's disease: Applying MRS, DTI, and ASL
期刊论文
2018, 卷号: 1698, 页码: 114-120
作者:
Shen, Zhiwei
;
Lei, Jianfeng
;
Li, Xueyuan
;
Wang, Zhanjing
;
Bao, Xinjie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Alzheimer's disease
MRI
MRS
ASL
DTI
APP/PS1 transgenic mice
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 页码: 9-28
作者:
Li, Cong[1]
;
Gu, Xiao-dan[2]
;
Lei, Min[3]
;
Wu, Jia-yi[4]
;
Jin, Jia-zhen[5]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/04/24
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
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