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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载:43/0  |  提交时间:2022/01/04
Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei 期刊论文
FRONTIERS IN MARINE SCIENCE, 2021, 卷号: 8, 页码: 12
作者:  Pang, Ying;  Zhang, Xiaojun;  Yuan, Jianbo;  Zhang, Xiaoxi;  Su, Manwen
收藏  |  浏览/下载:27/0  |  提交时间:2021/12/07
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载:49/0  |  提交时间:2021/05/24
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:  Liu, Jian-Guo;  Zhao, Danfeng;  Gong, Qi;  Bao, Fengxia;  Chen, Wen-Wen
收藏  |  浏览/下载:18/0  |  提交时间:2021/05/24
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Sun, Pu;  Meng, Ling-hua
收藏  |  浏览/下载:44/0  |  提交时间:2020/12/21
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Yan-Hong;  Wang, Yi;  Zhang, Xi;  Ding, Jian
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:  Guo, Chuanlong;  Wang, Lijun;  Zhao, Yue;  Jiang, Bo;  Luo, Jiao
收藏  |  浏览/下载:122/0  |  提交时间:2019/08/28
Wortmannine F and G, two new pyranones from Talaromyces wortmannii LGT-4, the endophytic fungus of Tripterygium wilfordii 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 115-118
作者:  Zhao, Jun-Wen;  Yang, Zhong-Duo;  Zhou, Shuan-Yan;  Yang, Li-Jun;  Sun, Jian-Hui
收藏  |  浏览/下载:46/0  |  提交时间:2019/11/15
Wortmannine F and G, two new pyranones from Talaromyces wortmannii LGT-4, the endophytic fungus of Tripterygium wilfordii 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 115-118
作者:  Zhao, Jun-Wen;  Yang, Zhong-Duo;  Zhou, Shuan-Yan;  Yang, Li-Jun;  Sun, Jian-Hui
收藏  |  浏览/下载:10/0  |  提交时间:2022/03/01


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