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CORC

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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：140/0  |  提交时间：2019/06/28
Modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation 期刊论文
British journal of pharmacology, 2019
作者:  Cao Yin[1];  Li Qinglin[2];  Liu Lulu[3];  Wu Hui[4];  Huang Fei[5]
收藏  |  浏览/下载：34/0  |  提交时间：2019/04/22
Effects of Different Preservation Methods on Physicochemical Property of Marine Pathogen Vibrio anguillarum 期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2019, 卷号: 18, 期号: 6, 页码: 1417-1426
作者:  Yu Yongxiang[1];  Zhang Zheng[2];  Wang Yingeng[3];  Liao Meijie[4];  Rong Xiaojun[5]
收藏  |  浏览/下载：7/0  |  提交时间：2020/01/02
Relationship between Wetland Plant Communities and Environmental Factors in the Tumen River Basin in Northeast China 期刊论文
SUSTAINABILITY, 2019, 卷号: 11, 期号: 6
作者:  Zheng, Xiaojun[1];  Fu, Jing[2];  Ramamonjisoa, Noelikanto[3];  Zhu, Weihong[4];  He, Chunguang[5]
收藏  |  浏览/下载：16/0  |  提交时间：2020/01/02
Responses of microbial community structure in turbot (Scophthalmus maximus) larval intestine to the regulation of probiotic introduced through live feed 期刊论文
PLOS ONE, 2019, 卷号: 14, 期号: 5
作者:  Jiang, Yan[1];  Wang, Yingeng[2];  Zhang, Zheng[3];  Liao, Meijie[4];  Li, Bin[5]
收藏  |  浏览/下载：8/0  |  提交时间：2020/01/02
Influences of immersion bathing in Bacillus velezensis DY-6 on growth performance, non-specific immune enzyme activities and gut microbiota of Apostichopus japonicus 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2019, 卷号: 37, 期号: 4, 页码: 1449-1459
作者:  Wang Jinyan[1];  Li Bin[2];  Wang Yingeng[3];  Liao Meijie[4];  Rong Xiaojun[5]
收藏  |  浏览/下载：66/0  |  提交时间：2020/01/02
Complete Genome Sequence of Photobacterium damselae Subsp. damselae Strain SSPD1601 Isolated from Deep-Sea Cage-Cultured Sebastes schlegelii with Septic Skin Ulcer 期刊论文
INTERNATIONAL JOURNAL OF GENOMICS, 2019
作者:  Yu, Yongxiang[1];  Zhang, Zheng[2];  Wang, Yingeng[3];  Liao, Meijie[4]
收藏  |  浏览/下载：7/0  |  提交时间：2020/01/02
Exploring the Binding Mechanism of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators in Clinical Trials by Molecular Dynamics Simulations 期刊论文
2018, 卷号: 9, 页码: 1492-1502
作者:  Fu, Tingting[1,2,3];  Zheng, Guoxun[1,2,3];  Tu, Gao[1,2,3];  Yang, Fengyuan[1,2,3];  Chen, Yuzong[4]
收藏  |  浏览/下载：10/0  |  提交时间：2019/11/28
What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation 期刊论文
2018, 卷号: 9, 页码: 1128-1140
作者:  Xue, Weiwei[1,2,3];  Yang, Fengyuan[1,2,3];  Wang, Panpan[1,2,3];  Zheng, Guoxun[1,2,3];  Chen, Yuzong[4]
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/30
Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder 期刊论文
2018, 卷号: 20, 页码: 6606-6616
作者:  Xue, Weiwei[1,2,3];  Wang, Panpan[1,2,3];  Tu, Gao[1,2,3];  Yang, Fengyuan[1,2,3];  Zheng, Guoxun[1,2,3]
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/30

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