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贵州大学 [22]
上海药物研究所 [8]
湖南大学 [6]
江苏大学 [3]
上海大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [42]
会议论文 [4]
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Structural basis of ketamine action on human NMDA receptors
期刊论文
NATURE, 2021, 卷号: 596, 期号: 7871, 页码: 301-+
作者:
Zhang, Youyi
;
Ye, Fei
;
Zhang, Tongtong
;
Lv, Shiyun
;
Zhou, Liping
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
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  |  
浏览/下载:76/0
  |  
提交时间:2021/08/17
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
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  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:
Zhu, Kongkai
;
Du, Daohai
;
Yang, Rui
;
Tao, Hongrui
;
Zhang, Hua
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
polycomb repressive complex 2
EZH2-EED interaction inhibitor
virtual screening
molecular dynamics simulation
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:
Shao, Jingwei
;
Zhu, Kongkai
;
Du, Daohai
;
Zhang, Yuanyuan
;
Tao, Hongrui
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
PRMT5 inhibitors
N-Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
Anti-tumor
Simulation and experimental study on the pump efficiency improvement of continuously variable transmission
期刊论文
Mechanism and Machine Theory, 2019, 卷号: Vol.131, 页码: 137-151
作者:
Qu, Daohai
;
Luo, Wei
;
Liu, Yunfeng
;
Fu, Bing
;
Zhou, Yunshan
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  |  
浏览/下载:24/0
  |  
提交时间:2019/12/13
Simulation and experimental study on the pump efficiency improvement of continuously variable transmission.
期刊论文
Mechanism & Machine Theory, 2019, 卷号: Vol.131, 页码: 137-151
作者:
Qu, Daohai
;
Luo, Wei
;
Liu, Yunfeng
;
Fu, Bing
;
Zhou, Yunshan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/13
Bench test
CVT
Power loss of pump
Smart mode
Software in loop simulation
Variable pump
Simulation and experimental study on the pump efficiency improvement of continuously variable transmission
期刊论文
MECHANISM AND MACHINE THEORY, 2019, 卷号: Vol.131, 页码: 137-151
作者:
Qu, Daohai
;
Luo, Wei
;
Liu, Yunfeng
;
Fu, Bing
;
Zhou, Yunshan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/13
CVT
Power loss of pump
Variable pump
Smart mode
Software in loop simulation
Bench test
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:
Zhang, Rukang
;
Wang, Jiang
;
Zhao, Liang
;
Liu, Shien
;
Du, Daohai
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
High throughput screening
Epigenetics
Histone acetyltransferase
MOF
Inhibitor
Sentiment topic mining based on comment tags
会议论文
2017 INTERNATIONAL SYMPOSIUM ON APPLICATION OF MATERIALS SCIENCE AND ENERGY MATERIALS (SAMSE 2017), 2018-01-01
作者:
Zhang, Daohai[1]
;
Liu, Xue[2]
;
Li, Juan[3]
;
Fan, Mingyue[4]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/24
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